Targeted Analyses of Jackson Heart Study Data

杰克逊心脏研究数据的针对性分析

基本信息

项目摘要

DESCRIPTION (provided by applicant): The Jackson Heart Study (JHS) was designed to collect clinical, laboratory, imaging, genetic, and environmental data that could provide insights into the determinants and development of cardiovascular and related diseases in African Americans (AA) residing in the Jackson, MS community. Between 2000 and 2012, 5301 AA men and women participated at a baseline and two additional clinic examinations. Obesity and diabetes are important contributors to cardiovascular outcomes and the overall health disparities observed between AAs and whites in the United States. Both conditions are highly prevalent among those enrolled in JHS. The overall goal of this proposal is to enhance the scientific output of the JHS with respect to obesity/diabetes and its cardiometabolic and vascular outcomes. We propose to conduct in-depth cross- sectional and longitudinal analyses of obesity and glucometabolic parameters, and select outcomes (incident diabetes, subclinical and clinical cardiovascular disease) by engaging scientists in the newly established JHS Obesity Diabetes Working Group (ODWG). The ODWG will function as a virtual team, utilizing a combination of teleconferences, in person meetings, and internet-based file sharing tools, and will include Wake Forest, JHS and other interested investigators and trainees. The investigative team includes expertise in epidemiology, biostatistics, imaging, diabetes, obesity, and cardiovascular disease. We also have an extant relationship with JHS as Wake Forest served as the reading center for the CT and MRI studies performed at exams 2 and 3. A focus of ODWG activities includes mentoring junior investigators and trainees. We also expect that analysis and dissemination of these data will spur the application for separate funding for ancillary studies.
描述(由申请人提供):杰克逊心脏研究(JHS)旨在收集临床、实验室、成像、遗传和环境数据,这些数据可以深入了解居住在MS杰克逊社区的非洲裔美国人(AA)心血管和相关疾病的决定因素和发展。 在2000年至2012年期间,5301名AA男性和女性参加了基线和两次额外的临床检查。 肥胖和糖尿病是心血管结局的重要因素,也是美国AA和白人之间观察到的总体健康差异的重要因素。这两种情况在参加JHS的人中非常普遍。该提案的总体目标是提高JHS在肥胖/糖尿病及其心脏代谢和血管结局方面的科学产出。 我们建议对肥胖和糖代谢参数进行深入的横断面和纵向分析,并通过新成立的JHS肥胖糖尿病工作组(ODWG)的科学家来选择结局(新发糖尿病,亚临床和临床心血管疾病)。 ODWG将作为一个虚拟团队发挥作用,利用电话会议、面对面会议和基于互联网的文件共享工具的组合,并将包括维克森林、JHS和其他感兴趣的调查人员和受训人员。调查小组包括流行病学、生物统计学、成像、糖尿病、肥胖和心血管疾病方面的专业知识。 我们与JHS也有现存的关系,因为维克森林是在检查2和3中进行的CT和MRI研究的阅读中心。观察员办公室的活动重点包括指导初级调查员和受训人员。我们还预计,这些数据的分析和传播将刺激辅助研究的单独资金申请。

项目成果

期刊论文数量(5)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
High-Sensitivity C-Reactive Protein Is Associated With Incident Type 2 Diabetes Among African Americans: The Jackson Heart Study.
  • DOI:
    10.2337/dc15-0221
  • 发表时间:
    2015-09
  • 期刊:
  • 影响因子:
    16.2
  • 作者:
    Effoe VS;Correa A;Chen H;Lacy ME;Bertoni AG
  • 通讯作者:
    Bertoni AG
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Alain Gerald Bertoni其他文献

Alain Gerald Bertoni的其他文献

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{{ truncateString('Alain Gerald Bertoni', 18)}}的其他基金

Transition from Risk Factors to Early HF: Prevalence, Pathogenesis, and Phenomics
从危险因素到早期心力衰竭的转变:患病率、发病机制和表型组学
  • 批准号:
    9313715
  • 财政年份:
    2015
  • 资助金额:
    $ 24.1万
  • 项目类别:
Transition from Risk Factors to Early HF: Prevalence, Pathogenesis, and Phenomics
从危险因素到早期心力衰竭的转变:患病率、发病机制和表型组学
  • 批准号:
    9115219
  • 财政年份:
    2015
  • 资助金额:
    $ 24.1万
  • 项目类别:
Training in Health Disparity Research for a Diverse Neuroscience Workforce
为多元化的神经科学劳动力提供健康差异研究培训
  • 批准号:
    9321076
  • 财政年份:
    2014
  • 资助金额:
    $ 24.1万
  • 项目类别:
Training in Health Disparity Research for a Diverse Neuroscience Workforce
为多元化的神经科学劳动力提供健康差异研究培训
  • 批准号:
    9125880
  • 财政年份:
    2014
  • 资助金额:
    $ 24.1万
  • 项目类别:
Targeted Analyses of Jackson Heart Study Data
杰克逊心脏研究数据的针对性分析
  • 批准号:
    8441279
  • 财政年份:
    2013
  • 资助金额:
    $ 24.1万
  • 项目类别:
Targeted Analyses of Jackson Heart Study Data
杰克逊心脏研究数据的针对性分析
  • 批准号:
    8862525
  • 财政年份:
    2013
  • 资助金额:
    $ 24.1万
  • 项目类别:
Targeted Analyses of Jackson Heart Study Data
杰克逊心脏研究数据的针对性分析
  • 批准号:
    8701389
  • 财政年份:
    2013
  • 资助金额:
    $ 24.1万
  • 项目类别:
The Maya Angelou Center for Health Equity
玛雅安杰卢健康公平中心
  • 批准号:
    9011378
  • 财政年份:
    2012
  • 资助金额:
    $ 24.1万
  • 项目类别:
TRANSLATING DIETARY TRIALS INTO THE COMMUNITY
将饮食试验转化为社区
  • 批准号:
    8167041
  • 财政年份:
    2010
  • 资助金额:
    $ 24.1万
  • 项目类别:
Determinants of Brain Natriuretic Peptide in Diabetes
糖尿病脑钠肽的决定因素
  • 批准号:
    7585555
  • 财政年份:
    2009
  • 资助金额:
    $ 24.1万
  • 项目类别:

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