Aberrant mesenchymal-epithelial transition: a pathogenic mechanism in tissue maintenance and differentiation

异常间充质-上皮转化：组织维持和分化的致病机制

• 批准号: nhmrc : 1066832
• 负责人: A/Pr Jonathan Arthur
• 金额: $ 34.83万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/aberrant-mesenchymal-epithelial-maintenance-differentiation/455262
• 关键词: Aberrant; mesenchymal; epithelial; transition; pathogenic

The causative genetic factors associated with aberrant changes of cellular properties are identified by analysing the profile and the control mechanism of gene expression. Specifically,this project will reveal how the transition of different patterns of tissue organization may be manifested in birth defects and malignant diseases.

通过分析基因表达谱和控制机制，确定与细胞特性异常变化相关的致病遗传因素。具体来说，该项目将揭示不同组织组织模式的转变如何在出生缺陷和恶性疾病中表现出来。