Systematic Light Exposure for Fatigue in Stem Cell Transplant Survivors
系统性光照可缓解干细胞移植幸存者的疲劳
基本信息
- 批准号:9028574
- 负责人:
- 金额:$ 72.55万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2016
- 资助国家:美国
- 起止时间:2016-01-01 至 2020-12-31
- 项目状态:已结题
- 来源:
- 关键词:Activities of Daily LivingAddressAdverse effectsAffectAutologousAutologous Stem Cell TransplantationBiologicalBoxingCancer InterventionCancer SurvivorCircadian RhythmsClinicalClinical TrialsCognitive TherapyDataExerciseExposure toFatigueHydrocortisoneHypnosisInterventionInvestigationLightMalignant NeoplasmsMeasuresMediatingMedicalMedical centerMultiple MyelomaNew York CityOutcomeParticipantPatientsPittsburgh Sleep Quality IndexProcessRandomizedRandomized Controlled TrialsRecommendationRecruitment ActivityReportingResearchSample SizeSamplingScheduleSelf-AdministeredSiteSleepStem cell transplantSurvivorsTimeVisitYogaactigraphyclinically significantcostdepressive symptomsefficacy testingexhaustionexperiencefollow-uplarge cell Diffuse non-Hodgkin&aposs lymphomalight effectsmeetingsmeternovelpatient populationpsychologicpublic health relevancerandomized trialtreatment duration
项目摘要
DESCRIPTION (provided by applicant): Cancer related fatigue (CRF) is the most common cancer side effect and can severely interfere with activities of daily living long after completionof medical treatment. Pharmacologic agents to treat CRF have been studied but there is insufficient evidence to recommend their use. Non-pharmacological interventions for CRF have also been studied but are costly to implement and involve significant patient burden. This study investigates a novel low-cost/low-burden intervention: systematic bright white light (BWL) exposure to treat CRF. Two hundred survivors of multiple myeloma and Diffuse Large B-cell Lymphoma between 100 and 160 days post-autologous stem cell transplant (ASCT) will be recruited from two medical centers and randomized to one of two conditions: BWL or dim red light (DRL), a common comparison condition in light studies. The BWL intervention consists of exposure to full spectrum bright light whereas the DRL condition will involve exposure to less intense red light (< 50 lux). Both groups will self-administer 30 minutes of light from identically
appearing boxes for 4 weeks. Outcomes will be assessed through standardized subjective and objective measures at five separate time points, including baseline and follow-up. The study will specifically address recommendations made for interventions for CRF from the NCI Clinical Trials Planning meeting (JNCI, 2013).The proposed study will: 1) be the first large multisite RCT with a carefully delineated comparison condition to investigate the effects of light on CRF among ASCT survivors; 2) focus on a distinct, homogenous patient population; 3) include only survivors who experience clinical levels of CRF; and 4) address possible psychological and biological mechanisms. This RCT will have major
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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William H Redd其他文献
William H Redd的其他文献
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{{ truncateString('William H Redd', 18)}}的其他基金
Systematic Light Exposure to treat Cancer-Related Fatigue in Breast Cancer Patients
系统性光照治疗乳腺癌患者与癌症相关的疲劳
- 批准号:
9310766 - 财政年份:2017
- 资助金额:
$ 72.55万 - 项目类别:
Systematic Light Exposure to treat Cancer-Related Fatigue in Breast Cancer Patients
系统性光照治疗乳腺癌患者与癌症相关的疲劳
- 批准号:
9927596 - 财政年份:2017
- 资助金额:
$ 72.55万 - 项目类别:
Systematic Light Exposure to treat Cancer-Related Fatigue in Breast Cancer Patients
系统性光照治疗乳腺癌患者与癌症相关的疲劳
- 批准号:
10231010 - 财政年份:2017
- 资助金额:
$ 72.55万 - 项目类别:
Systematic Programmed Illumination (sPI) of Hospital Rooms to Prevent/Reduce Cancer-Related Fatigue During Hematopoeitic Stem Cell Transplantation for Multiple Myeloma
医院病房的系统程序照明 (sPI) 可预防/减少多发性骨髓瘤造血干细胞移植期间与癌症相关的疲劳
- 批准号:
9322328 - 财政年份:2016
- 资助金额:
$ 72.55万 - 项目类别:
Systematic Light Exposure for Fatigue in Stem Cell Transplant Survivors
系统性光照可缓解干细胞移植幸存者的疲劳
- 批准号:
9191356 - 财政年份:2016
- 资助金额:
$ 72.55万 - 项目类别:
Treating Cancer-Related Cognitive Impairment Through Systematic Light Exposure
通过系统光照治疗与癌症相关的认知障碍
- 批准号:
8900244 - 财政年份:2014
- 资助金额:
$ 72.55万 - 项目类别:
Treating Cancer-Related Cognitive Impairment Through Systematic Light Exposure
通过系统光照治疗与癌症相关的认知障碍
- 批准号:
8752903 - 财政年份:2014
- 资助金额:
$ 72.55万 - 项目类别:
Treating Cancer-Related Fatigue Through Systematic Bright White Light
通过系统亮白光治疗与癌症相关的疲劳
- 批准号:
8196046 - 财政年份:2011
- 资助金额:
$ 72.55万 - 项目类别:
Treating Cancer-Related Fatigue Through Systematic Bright White Light
通过系统亮白光治疗与癌症相关的疲劳
- 批准号:
8306110 - 财政年份:2011
- 资助金额:
$ 72.55万 - 项目类别:
CBT Training For Clinicians Providing Supportive Care For Cancer Survivors
为癌症幸存者提供支持性护理的临床医生进行 CBT 培训
- 批准号:
7923919 - 财政年份:2009
- 资助金额:
$ 72.55万 - 项目类别:
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