ANTECEDANTS SEQUELAE OF CHILDHOOD ONSET DISEASE

儿童期发病的前因后果

• 批准号: 9220846
• 负责人: Julio PEREZ FONTAN
• 金额: $ 20.17万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-12-05 至 2020-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9220846
• 关键词: Appointment; Award; Basic Science; Child; Child Support; Child health care; Childhood; Clinical; Collaborations; Development; Disease; Experimental Designs; Goals; Imagination; Infant; Instruction; K-Series Research Career Programs; Maintenance; Medical center; Mentors; Onset of illness; Pediatrics; Physicians; Positioning Attribute; Process; Research; Research Personnel; Research Training; Resources; Scientist; Stream; Supervision; Talents; Teacher Professional Development; Technology; Texas; Time; United States National Institutes of Health; Universities; Vocational Guidance; beneficiary; career; clinically relevant; collaborative environment; experience; next generation; pediatric department; programs; success

 DESCRIPTION (provided by applicant): This is a competitive renewal application for continued support of the Child Health Research Career Development Award (CHRCDA) Program in the Department of Pediatrics at the University of Texas Southwestern Medical Center (UTSW). UTSW and its Department of Pediatrics are ideally positioned to provide the supportive environment, the dedicated mentors, the critical core resources, and, most importantly, the stream of talented clinician-scientists that become the ultimate beneficiaries of this award. Our goal is to motivate and enable these young scientists to become the next generation of imaginative, independent, and sophisticated investigators focused on the diseases of major importance to infants and children throughout their lifetimes. We believe that our CHRCDA Program is uniquely qualified to accomplish this goal for the following reasons: 1) we have assembled a training faculty that offers enormous subject diversity, spanning nine university departments and four autonomous centers, and is at the same time uniformly focused on the developmental theme of our CHRCDA; 2) the biologic processes that we have identified for study are not only critically important to pediatrics, but also leverage existing strengths and well-established research and training collaborations between basic science and clinical departments at UT Southwestern; 3) recognizing that there has been no other time when the need to promote research careers among young physicians has been more crucial, our Department is committed to identifying the best candidates from an early stage and providing them with the encouragement and resources requisite to successful development into independent pediatric physician-scientists with a passion for discovery; and 4) despite its short course of four years, our Program has demonstrated its ability to achieve the goals established by NIH for the CHRCDA as evidenced by the success of all three of our graduating scholars in obtaining K08 or equivalent federal support either during their participation in the Program or within one year of their graduation. The CHRCDA Program at UT Southwestern will support a maximum of four Scholars at a time, each receiving an appointment of two years (which may be extended to three). During their participation in the Program, the Scholars will follow a personalized plan for research instruction and will dedicate a minimum of 80% of their effort to a rigorous research plan under the supervision of a mentor. Each Scholar's experience will continue to emphasize the identification of compelling clinically-relevant scientific questions, maintenance of project focus, creative experimental design, state-of-the-art technology, and thoughtful early career guidance.

 描述（由申请人提供）：这是一份竞争性续签申请，旨在继续支持德克萨斯大学西南医学中心 (UTSW) 儿科部门的儿童健康研究职业发展奖 (CHRCDA) 计划。 UTSW 及其儿科部门处于理想的位置，可以提供支持性环境、敬业的导师、关键的核心资源，以及最重要的是，成为该奖项最终受益者的才华横溢的临床医生科学家。我们的目标是激励并使这些年轻科学家成为下一代富有想象力、独立且经验丰富的研究人员，专注于对婴儿和儿童一生至关重要的疾病。我们相信，我们的 CHRCDA 项目具有独特的资格来实现这一目标，原因如下：1) 我们组建了一支培训师资队伍，提供巨大的学科多样性，涵盖九个大学系和四个自治中心，同时统一关注我们 CHRCDA 的发展主题； 2）我们确定的研究生物学过程不仅对儿科至关重要，而且还利用了现有的优势和 德克萨斯大学西南医学中心基础科学和临床部门之间建立了良好的研究和培训合作关系； 3) 认识到促进年轻医生研究生涯的需要比以往任何时候都更加重要，我们部门致力于从早期阶段识别最佳候选人，并为他们提供必要的鼓励和资源，帮助他们成功发展成为充满探索热情的独立儿科医师科学家； 4) 尽管课程为期四年，但我们的计划已证明其有能力实现 NIH 为 CHRCDA 制定的目标，我们的三位毕业生学者在参与该计划期间或毕业后一年内均成功获得了 K08 或同等联邦支持，这证明了这一点。 UT 西南大学的 CHRCDA 项目一次最多支持四名学者，每名学者的任期为两年（可延长至三年）。在参与该计划期间，学者们将遵循个性化的研究指导计划，并在导师的监督下将至少 80% 的精力投入到严格的研究计划中。每位学者的经验将继续强调确定引人注目的临床相关科学问题、保持项目重点、创造性的实验设计、最先进的技术和深思熟虑的早期职业指导。