ASPREE-D; Aspirin in the prevention of depression in the elderly

ASPREE-D；

• 批准号: nhmrc : 1081901
• 负责人: A/Pr Robyn Woods
• 金额: $ 53.13万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/aspree-d-aspirin-depression-elderly/518836
• 关键词: ASPREE; Aspirin; prevention; depression; elderly

The ASPREE (ASPirin in Reducing Events in the Elderly) study is a 5 year RCT of aspirin (100mg daily) or placebo in 19,000 healthy people over 70. We aim to augment the existing infrastructure of ASPREE in order to confirm the utility of aspirin for the prevention of depression in the elderly (ASPREE-D). The primary aim of ASPREE-D is to determine if use of low-dose aspirin reduces the incidence of de-novo episodes of depression in healthy individuals over 70 years of age.

ASPREE（ASPirin 减少老年人事件）研究是一项针对 19,000 名 70 岁以上健康人的阿司匹林（每天 100 毫克）或安慰剂的随机对照试验。我们的目标是增强 ASPREE 的现有基础设施，以确认阿司匹林在预防老年人抑郁症方面的效用 (ASPREE-D)。 ASPREE-D 的主要目的是确定使用低剂量阿司匹林是否可以降低 70 岁以上健康个体抑郁症新发的发生率。