Research Core 2: Physical Measurements Core (RC2)

项目摘要/摘要--实物测量核心(PMC) 对于从事与我们主题相关的研究的调查人员来说，一个重要的考虑因素是“理解和 优化储备和韧性“是如何选择和实施最合适和最有意义的 措施。物理测量核心将通过充当中心的中心资源来提供此服务 调查人员寻求建议、培训、实验室准入和设备，以确保有效、敏感和可靠 措施。一个由13名成员组成的小组，在跨多个领域的测量方面拥有互补的专业知识， 由核心组成。物理测量核心将提供高度集成的定制支持，以 由我们的研究教育部分，试点/探索性研究核心，外部支持的调查人员 资助的项目，以及由公爵老年美国人独立协会参与的更大的杜克社区 中心。核心将通过在整个项目范围内定期举行会议来支持调查人员 发展，从早期阶段规划，到对调查结果的最终解释，再到随后的赠款准备 传播和/或实施。这些会议将同时有分析和分析小组成员参加 分子措施的核心是确保最大的协同效应。我们提出了三个具体目标。目标1--提供 关于衡量准备金和复原力的咨询可用的集中专门知识。目标2--目标 制定测量方案，培训管理人员和数据收集人员。目标3-确定 弹性测量方面的差距，并在成人中开发或采用创新的新测量方法 相关结果的寿命。五名REC学者和两名PES获奖者的项目将在#年得到支持 前两年的资金。管理委员会成员还将为五名环保人员提供服务，并提出 创新“新兴发现计划”开发两种测量肌肉储备和功能的新工具 使用电阻抗肌图和定量肌肉超声检查。计划举办两个研讨会，一个是 提供身体性能和功能测试方面的培训，以及一名提供非卧床培训 测量和数据收集，以增强我们受训人员的测量能力；如果成功，这些 讲习班可传播给其他OAIC。PMC将为我们的中心提供无价的服务， 这将导致对储备和韧性的更好理解，这反过来将指向机会 以改善老年美国人目前和未来的健康和福祉。

PROJECT SUMMARY/ABSTRACT – Physical Measures Core (PMC) An important consideration for investigators undertaking studies relevant to our theme “To Understand and Optimize Reserve and Resilience” is how to select and implement the most appropriate and meaningful measures. A Physical Measures Core will provide this service by serving as the central resource for Center investigators seeking advice, training, laboratory access, and equipment for valid, sensitive, and reliable measures. A panel of 13 members, with complementary expertise in measurement across multiple domains, comprises the Core. The Physical Measures Core will provide highly integrated, customized support to investigators supported by our Research Education Component, Pilot/Exploratory Studies Core, Externally Funded Projects, and the larger Duke Community engaged by the Duke Older Americans Independence Center. The Core will support investigators by meeting regularly throughout the full spectrum of project development, from early phase planning, to final interpretation of findings, to subsequent grant preparations to dissemination and/or implementation. These meetings will concurrently involve members of the Analysis and Molecular Measures Cores to assure maximal synergy. We propose three Specific Aims. Aim 1 - To provide centralized expertise available for consultation on the measurement of reserve and resilience. Aim 2 - To develop measurement protocols and train personnel in administration and data collection. Aim 3 - To identify gaps in resiliency measures and develop or adapt innovative new measurement approaches across the adult lifespan for related outcomes. Projects for five REC Scholars and two PES awardees will be supported during the first two years of funding. Members of the PMC will also provide service to five EPs, and propose an innovative “Emerging Discovery Project” to develop two new tools to measure muscle reserve and function using electrical impedance myography and quantitative muscle ultrasound. Two workshops are proposed, one to provide training in physical performance and functional testing, and one to provide training in ambulatory measurement and data collection, to augment the measurement capabilities of our trainees; if successful these workshops can be disseminated to other OAICs. The PMC will provide an invaluable service to our Center, which will lead to greater understanding of reserve and resilience, and which in turn, will point to opportunities to improve the current and future health and well-being of aging Americans across the lifespan.