Meeting Community Needs Across the Prevention Spectrum

描述（由申请人提供）：耶鲁-格里芬预防研究中心以满足整个预防领域的社区需求为初衷，继续致力于慢性病一级、二级和三级预防的研究，特别强调肥胖的预防。该中心的具体目标是： 维护和培养必要的资源和基础设施，以支持蓬勃发展的研究议程；维持和发展符合中华人民共和国使命的研究议程；支持核心研究项目，该项目将作为全国中华人民共和国网络和全国社区的典范；发展与当地社区的合作和伙伴关系网络；支持和促进他人的相关研究；为员工、学生、合作者以及合作组织和社区的成员提供培训和教育；支持稳健且动态的评估计划；进行有效的沟通和传播；并维持这些职能所需的资源。 Y-G PRC 即将到来的 5 年周期的主要研究议程是通过使用多地点转化社区试验 (mTCT)1 方法来解决 CDC 营养、身体活动和肥胖方面的“必胜之战”领域，其中在多个地点应用标准研究方案和干预措施，并使用 CBPR 原则进行定制，以满足每个社区的需求。主要研究 CHOOSE（与震中学校一起组织的社区健康机会）是一项干预研究项目，涉及康涅狄格州、密苏里州和堪萨斯州的社区，并需要从作为震中的学区开始进行干预，并在学校内外扩展到整个各自社区的其他“门户”。我们计划使用准实验方法比较 4 个干预水平（参见附录 J），其结果涵盖行为、生物识别和人体测量。康涅狄格州纽黑文市将采用类似的方法，但重点是以患者/医院为中心，而不是以学校为中心的规划。在每种情况下，我们都计划通过量身定制的多学科干预措施来接触合作社区内的群体，并随着时间的推移汇总总体影响和影响范围。研究目标是改善学龄儿童和成人的饮食和身体活动；次要目标是改善儿童和成人的心脏代谢健康以及儿童的学业成绩，每项措施都与经过验证的评估方法相关。将利用过去 15 年中有效利用的一系列已建立的伙伴关系来传播和可持续发展，以最大限度地发挥这项工作的影响。

DESCRIPTION (provided by applicant): Building on its original mission of Meeting Community Needs Across the Prevention Spectrum, the Yale-Griffin Prevention Research Center remains committed to research pertaining to the primary, secondary, and tertiary prevention of chronic disease, with a particular emphasis on obesity prevention. The specific aims of the Center are to: maintain and cultivate the requisite resources and infrastructure to support a thriving research agenda; sustain and grow a research agenda that corresponds with the PRC's mission; support a core research project that will serve as a model for the National PRC Network and communities nationwide; grow a network of collaborations and partnerships with local communities; support and facilitate relevant research by others; provide training and education to staff, students, collaborators, and the members of partnering organizations and communities; support a robust and dynamic evaluation program; engage in effective communication and dissemination; and maintain the requisite resources for these functions. The Y-G PRC's primary research agenda for the upcoming 5-year cycle is to address the CDC "winnable battle" area of nutrition, physical activity, and obesity by using a multisite translatioal community trial (mTCT)1 approach, wherein a standard research protocol and intervention are applied in multiple sites, with tailoring using CBPR principles to meet the needs of each community. The primary study, CHOOSE (Community Health Opportunities Organized with Schools at the Epicenter), an intervention research project, involves communities in CT, MO, and KS, and entails interventions commencing with school districts as epicenters, and expanding within and beyond schools into other "portals" throughout their respective communities. We plan to compare 4 levels of intervention (See Appendix J) using quasi- experimental methods, with outcomes encompassing behaviors, biometrics, and anthropometrics. A similar approach will be applied in New Haven, CT, but with a focus on patient/hospital-centered rather than school- centered programming. In each case, we plan to reach groups within partnering communities with tailored multidisciplinary interventions, and aggregate the total impact and reach over time. Study objectives are to improve diet and physical activity in school-aged children and adults alike; with secondary goals of improving cardiometabolic health in both children and adults, and academic performance in children, with each measure linked to a validated assessment method. An array of established partnerships used effectively over the past 15 years for dissemination and sustainability will be leveraged to maximize the impact of this work.