Driving Biomedical Projects 1-Mitochondrial phophorylatioon signaling
Driving Biomedical Projects 1-Mitochondrial phophorylatioon signaling
批准号:
9343432
负责人:
David J Pagliarini
金额:
$12.59万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
中文摘要
项目摘要
要最大限度地发挥每个DBP项目的影响,需要经常沟通,以便我们充分了解
正在解决的生物问题的性质,以及合作调查员(S)充分理解
每种可用技术的能力。我们会继续与各DBP的调查人员积极合作
为每个项目优化并实施最有效的实验设计。我们衡量成功的标准
一个DBP项目的完成是出版,我们希望完全参与创作每一份手稿。因此,
我们还将积极与每一位DBP合作者合作,设计、建造和修改我们
将在顶级期刊上发表。我们的目标是每个DBP项目至少产生一份出版物。这
战略还将帮助将中心技术传播给新的受众,即合作者的受众
生物医学专业领域。随着我们投资组合中每个DBP的进步,我们将积极寻找新的项目。我们
预计许多新的DBP将自然地从C&S部分列出的拟议工作演变而来,如下所示
项目继续初具规模。我们还将继续积极寻找新陈代谢领域的领导者。
在广泛的地理区域开展生物医学项目,以启动与我们现有工作协同的DBP项目。
我们将继续保持较高的DBP项目受理门槛,积极筛选和
只选择那些我们认为最具挑战性和最有影响力的。
英文摘要
Project Summary
Maximizing the impact of each DBP project requires frequent communication so that we fully understand the
nature of the biological problem being addressed and that the collaborating investigator(s) fully understand the
capabilities of each available technology. We will continue to work actively with the investigators of each DBP
to optimize and implement the most effective experimental design for each project. Our metric for successful
completion of a DBP project is publication and we expect to fully engage in authoring each manuscript. As such,
we will likewise actively work with each DBP collaborator to design, construct, and revise manuscripts that we
will target for publication in top journals. We aim for every DBP project to generate at least one publication. This
strategy will also aid in disseminating the center technologies to new audiences, those of the collaborator's
biomedical specialty field. As each DBP in our portfolio progresses, we will actively seek out new projects. We
expect that many new DBPs will naturally evolve from the proposed work listed under the C&S section as those
projects continue to take form. We will also continue to proactively seek out leaders in the fields of metabolism
and biomedicine across a broad geographical area to initiate DBP projects that synergize with our existing work.
We will continue to maintain a high bar for acceptance of DBP projects by actively screening proposals and
selecting only those that we deem to be the most challenging and high-impact.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Systems-to-structure approaches for defining mitochondrial protein function
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批准号:10592293
-
项目类别:
-
资助金额:$64.58万
-
财政年份:2019
-
负责人:David J Pagliarini
-
依托单位:
Systems-to-structure approaches for defining mitochondrial protein function
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批准号:10370341
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项目类别:
-
资助金额:$64.58万
-
财政年份:2019
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负责人:David J Pagliarini
-
依托单位:
Technologies for PTM discovery and functional mapping p. 505
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批准号:8998786
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项目类别:
-
资助金额:$7.33万
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财政年份:2016
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负责人:David J Pagliarini
-
依托单位:
Driving Biomedical Projects 1-Mitochondrial phophorylatioon signaling
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批准号:8998787
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项目类别:
-
资助金额:$35.19万
-
财政年份:2016
-
负责人:David J Pagliarini
-
依托单位:
Establishing the role of the atypical kinase ADCK3 in mitochondrial metabolism
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批准号:8900321
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项目类别:
-
资助金额:$7.42万
-
财政年份:2014
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负责人:David J Pagliarini
-
依托单位:
Establishing the role of the atypical kinase ADCK3 in mitochondrial metabolism
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批准号:8765976
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项目类别:
-
资助金额:$31.79万
-
财政年份:2014
-
负责人:David J Pagliarini
-
依托单位:
Regulation of Mitochondrial Function by Orphan Protein Phosphatases
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批准号:10221674
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项目类别:
-
资助金额:$44.39万
-
财政年份:2013
-
负责人:David J Pagliarini
-
依托单位:
Regulation of Mitochondrial Metabolism by Post-Translational Modifications
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批准号:8482787
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项目类别:
-
资助金额:$32.38万
-
财政年份:2013
-
负责人:David J Pagliarini
-
依托单位:
Regulation of Mitochondrial Function by Orphan Protein Phosphatases
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批准号:10405514
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项目类别:
-
资助金额:$43.1万
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财政年份:2013
-
负责人:David J Pagliarini
-
依托单位:
Regulation of Mitochondrial Metabolism by Post-Translational Modifications
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批准号:9262822
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项目类别:
-
资助金额:$30.16万
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财政年份:2013
-
负责人:David J Pagliarini
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依托单位:
Quantitative Mitochondrial Proteomics of Healthy and Diabetic Mice
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批准号:7937890
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项目类别:
-
资助金额:$43.72万
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财政年份:2009
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负责人:David J Pagliarini
-
依托单位:
Quantitative Mitochondrial Proteomics of Healthy and Diabetic Mice
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批准号:7821060
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项目类别:
-
资助金额:$47.54万
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财政年份:2009
-
负责人:David J Pagliarini
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依托单位:
海外基金