Driving Biomedical Projects 1-Mitochondrial phophorylatioon signaling

推动生物医学项目 1-线粒体磷酸化信号传导

• 批准号: 8998787
• 负责人: David J Pagliarini
• 金额: $ 35.19万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-05 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8998787
• 关键词: Address; Area; Automobile Driving; Biological; Biology; Collaborations; Communication; Complex; Experimental Designs; Journals; Manuscripts; Metabolism; Mitochondria; Nature; Publications; Research Personnel; Signal Transduction; System; Technology; Work; design and construction; medical specialties; screening

Project Summary Maximizing the impact of each DBP project requires frequent communication so that we fully understand the nature of the biological problem being addressed and that the collaborating investigator(s) fully understand the capabilities of each available technology. We will continue to work actively with the investigators of each DBP to optimize and implement the most effective experimental design for each project. Our metric for successful completion of a DBP project is publication and we expect to fully engage in authoring each manuscript. As such, we will likewise actively work with each DBP collaborator to design, construct, and revise manuscripts that we will target for publication in top journals. We aim for every DBP project to generate at least one publication. This strategy will also aid in disseminating the center technologies to new audiences, those of the collaborator's biomedical specialty field. As each DBP in our portfolio progresses, we will actively seek out new projects. We expect that many new DBPs will naturally evolve from the proposed work listed under the C&S section as those projects continue to take form. We will also continue to proactively seek out leaders in the fields of metabolism and biomedicine across a broad geographical area to initiate DBP projects that synergize with our existing work. We will continue to maintain a high bar for acceptance of DBP projects by actively screening proposals and selecting only those that we deem to be the most challenging and high-impact.

项目摘要 为了最大限度地发挥每个DBP项目的影响，需要经常进行沟通，以便我们充分了解 所处理的生物学问题的性质，并且合作研究者完全理解 每一项现有技术的能力。我们将继续与各DBP的调查人员积极合作 为每个项目优化和实施最有效的实验设计。我们衡量成功的标准 一个DBP项目的完成是出版，我们希望充分参与创作每一个手稿。因此，在本发明中， 我们也将积极与DBP的每一位合作者合作，设计、构建和修改我们需要的手稿。 将在顶级期刊上发表。我们的目标是每个DBP项目至少产生一个出版物。这 该战略还将有助于将中心的技术传播给新的受众， 生物医学专业领域随着我们投资组合中每个DBP的进展，我们将积极寻找新项目。我们 我预计，许多新的设计和施工方案将自然地从C&S部分列出的拟议工作中发展出来， 项目继续形成。我们还将继续积极寻找代谢领域的领导者 和生物医学在广泛的地理区域，以启动DBP项目，协同我们现有的工作。 我们会继续积极筛选建议书， 只选择我们认为最具挑战性和影响力的项目。