Core 2: Instrumentation Support Shared Resource

“核心2：仪器，探针和软件”的总体目标是提供仪器 为每个拟议的研究项目提供技术支持，以提高其生产力， 成本效益，并确保实现拟议的研究成果，以及 建立优化的仪器、探头和软件设计， 推广使用这项技术。该核心将利用现有的技术开发的 调查人员，并侧重于部署，支持和维护，而不是新的技术 发展理念支持将包括部署优化的硬件、软件和 顺磁探针需要作出有效和准确的测量氧气在 并在所有项目现场提供仪器的基本维护 为了有效运作。虽然现有的仪器已经是合适的，并已使用 对于有效的临床测量，有一些仪器改进， 达特茅斯在临床EPR方面的独特经验可以进一步提高该技术。在 此外，这三个项目将提供投入，以满足 仪器在特定的临床条件下，以及他们对数据输出类型的需求， 将在临床上非常有用。硬件改进将与 与三个主要项目有关的具体人员。同样，工具软件 将与主要项目以及科学和技术合作， 行政支助核心。

The overall goal of "Core 2 : Instrumentation, probes, and software" is to provide instrumental and technical support to each of the proposed research projects to enhance their productivity, cost-effectiveness, and ensure attainment of the proposed research outcomes, as well as establishment of optimized instrumentation, probe, and software designs for long-range wide- spread use of the technology. The Core will leverage existing technologies developed by the investigators, and focus on deployment, support, and maintenance as opposed to new technical developments. Support will include deployment of optimized hardware, software, and paramagnetic probes needed to make effective and accurate measurements of oxygen in human subjects and to provide the essential maintenance of the instruments at all projects sites for effective operation. While the existing instrumentation already is suitable and has been used for effective clinical measurements there are some instrumental refinements that build on the unique experience at Dartmouth in clinical EPR that could further enhance the technique. In addition, the three projects will provide input as to additional needs for operation of the instrument under specific clinical conditions and also their needs for the type of data output that will be most useful clinically. The hardware refinements will be done in collaboration with specific personnel associated with the three main projects. Similarly, the instrumental software refinements will be done in collaboration with the main projects and also the Scientific & Administrative Support Core.