Training for Transformative Discovery in Psychiatry

精神病学变革性发现培训

• 批准号: 9397125
• 负责人: ROBERT A SWEET
• 金额: $ 0.34万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9397125
• 关键词: Psychiatry; Training

 DESCRIPTION (provided by applicant): This proposal requests support for continuation of T32 MH16804 (Years 36-40). The most recent renewal (Years 31-35) proposed to reinvigorate this long term successful T32 by shifting the emphasis of training from predominantly clinical research to one providing translational neuroscience research training. We can now report that this transition has been highly successful as evidenced by a number of metrics: recruitment of translational neuroscience investigators, including increased numbers of M.D., Ph.D. trainees, female trainees, minority trainees, and trainees with disabilities; high rates of first grant fundig of graduates; research quality (as measured by the impact factor of journals in which appointees have published), and; successful placement of graduates. The achievements of T32 MH16084 have been mirrored by a substantial expansion of the Faculty of the Translational Neuroscience Program within the Department of Psychiatry at the University of Pittsburgh, and a corresponding increase in the number of outstanding applicants, such that the annual number of eligible applicants has exceeded our slots 10-fold. As a result, we look to expand the number of postdoctoral trainee slots in the current application to a total of five. This will afford opportunties to these many outstanding candidates and provide a greater "critical mass" for translational neuroscience training activities. All trainees benefit from our established training program in translational neuroscience which has been designed to provide practical training in techniques and strategies such that trainees' resulting research can be translated across multiple levels of discovery. Trainees with prior basic neuroscience training further receive clinical exposures designed to help them develop "fluency" in the clinical, pathophysiologic, and pathologic manifestations of mental illness, and; clinically trained individuals enhance their "fluency" in basic neuroscience knowledge. In addition, our trainees benefit from the development of individualized training plans and from participation in our highly successful Career and Research Development curriculum. T32 MH16804 continues to be led by Robert A. Sweet, M.D., a senior translational neuroscience investigator with a record of outstanding mentorship of translational neuroscience investigators. Dr. Sweet will be supported by new Co- Director, Mary L. Phillips, M.D., M.D. (Cantab), a senior clinical and translational neuroscience investigator and acclaimed mentor of imaging neuroscience investigators. Our Program Faculty has been enriched by a number of investigators who bring many additional state of the art approaches to translational neuroscience studies of mental illness. By combining the strong track record in the successful training of psychiatry researchers established during the past 34 years with the emphasis on new discovery and new methodologies developed during the past 4 years of funding, T32 MH16804 is now poised to impact the field by preparing an expanded cohort of translational neuroscientists to make transformative discoveries in psychiatry.

 描述(由申请人提供)：本提案请求支持继续使用T32 MH16804(36-40年)。最近的更新(31-35年)建议通过将培训的重点从主要的临床研究转移到提供转化性神经科学研究培训来重振这一长期成功的T32。我们现在可以报告说，这一过渡非常成功，这体现在一些指标上：招募了翻译神经科学研究人员，包括医学博士、博士实习生、女性实习生、少数族裔实习生和残疾实习生的人数增加；毕业生的第一笔赠款资助率很高；研究质量(以被任命者在其上发表文章的期刊的影响系数衡量)，以及毕业生的成功安置。与T32 MH16084的成就相对应的是，匹兹堡大学精神病学系内的翻译神经科学计划学院大幅扩大，杰出申请者的数量也相应增加，因此每年符合条件的申请者数量已经超过了我们名额的10倍。因此，我们希望将目前申请的博士后实习生名额扩大到总共五个。这将为这些优秀的候选人提供机会，并为翻译神经科学培训活动提供更大的“临界量”。所有受训者都受益于我们建立的翻译神经科学培训计划，该计划旨在提供技术和策略方面的实践培训，使受训者的研究成果可以在多个层次的发现中得到转化。接受过基础神经科学培训的受训者进一步接受临床暴露，旨在帮助他们在精神疾病的临床、病理生理学和病理学表现方面培养“流利性”，以及；受过临床培训的个人提高他们在基础神经科学知识方面的“流畅性”。此外，我们的学员还受益于制定个性化的培训计划，以及参加我们非常成功的职业和研究发展课程。T32 MH16804继续由罗伯特·A·斯威特医学博士领导，他是一位资深翻译神经科学研究员，拥有翻译神经科学研究者杰出导师的记录。斯威特博士将得到新任联席主任玛丽·L·菲利普斯医学博士(Canab)的支持，她是一名高级临床和翻译神经科学研究员， 备受赞誉的成像神经科学研究人员的导师。我们的计划学院得到了许多研究人员的丰富，他们为精神疾病的翻译神经科学研究带来了许多额外的最先进的方法。T32 MH16804结合了在过去34年中建立的精神病学研究人员成功培训的强劲记录，以及对过去4年资助期间开发的新发现和新方法的重视，现在准备通过准备一支更大的翻译神经科学家队列来在精神病学方面做出变革性的发现，从而影响该领域。