National Antimicrobial Resistance Monitoring System for Louisiana

路易斯安那州国家抗菌素耐药性监测系统

• 批准号: 9336880
• 负责人: Raoult Ratard
• 金额: $ 11.5万
• 依托单位: LOUISIANA STATE OFFICE OF PUBLIC HEALTH
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2021-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9336880
• 关键词: National; Antimicrobial; Resistance; Monitoring; System

NARMS Cooperative Agreement Program to Enhance and Strengthen Antibiotic Resistance Surveillance in Retail Food Specimens Agency Funding Opportunity Number: PAR-16-099 Louisiana Project Summary The excessive use of antibiotics in food animals can lead to the presence of antibiotic resistant bacteria in retail meat products. This in turn can lead to antibiotic resistant infections in humans. The retail meat program monitors trends in antibiotic resistance in retail meat items. The staff from IDES will purchase 80 retail meat samples per month split into two sampling trips of 5 stores per trip. The following will be purchased from each store: 5 chicken parts, 2 ground turkey, 1 pork chop, 1 ground beef. Different brands of the same commodity are to be purchased at each store. If that is not possible, items with different lot codes or sell by dates will be purchased. The items will be purchased from the stores on the grocery store sampling list. The meat samples will be transported to the State Public Health Laboratory in Baton Rouge for processing and testing per protocol. Isolated Salmonella and Campylobacter will be shipped to FDA for NARMS testing. PFGE will be performed on Salmonella isolates at the State Lab and patterns will be uploaded to PulseNet. IDES staff and laboratorian will maintain the NARMS logsheets and submit them to FDA. They will also maintain the FDA quarterly results on Louisiana isolates and compare them to Louisiana results for accuracy and quality control. For the first 12 months of this grant cycle, the expected outcomes are the continuation of purchasing, processing, and testing 80 meat samples per month and the continuation of shipping isolates to FDA for NARMS testing. Expected outputs include a decrease in the turn-around time from Salmonella isolation to upload of patterns to PulseNet and an increase in antibiotic resistant data on Salmonella and Campylobacter to be used with other states' data at FDA. Over the five year project period, the expected outputs are a successful retail meat program for the State of Louisiana and quality retail meat surveillance data for FDA NARMS to use in addition to the data they receive from other states. This increase in quality data can help influence policy regarding antimicrobial use. The expected outcomes for the five year period includes: 1) the successful completion of the purchasing, processing, and testing of 80 meat samples per month. 2) Decreased turn-around time from Salmonella isolation to testing at the State PFGE lab and pattern upload to PulseNet which could lead to an increase in the outbreaks investigated and solved associated with Salmonella in retail meat products. 3) The increase in antimicrobial resistance data specific to Louisiana will be analyzed for trends.

NARMS提高和加强抗生素耐药性合作协议计划 零售食物样本的监察 机构资助机会编号：PAR-16-099 路易斯安那 项目摘要 食用动物过量使用抗生素可导致抗生素 零售肉制品中的耐药细菌。这反过来又会导致抗生素耐药性感染， 人类零售肉类项目监测零售肉类中抗生素耐药性的趋势。 IDES的工作人员将每月购买80个零售肉类样本，分为两部分 每趟5家门店的抽样行程。以下将从每个商店购买：5鸡 2份火鸡肉，1份猪排，1份牛肉末。同一种商品的不同品牌 在每个商店购买。如果这是不可能的，项目与不同的批号或销售 日期将被购买。这些物品将从杂货店的商店购买 抽样清单这些肉类样本将于2013年被运送到国家公共卫生实验室。 根据方案在巴吞鲁日进行处理和试验。分离的沙门氏菌和弯曲杆菌 将被运送到FDA进行NARMS测试。将对沙门氏菌分离株进行PFGE， 州实验室和模式会上传到脉冲网络IDES工作人员和实验室人员将 维护NARMS日志表并将其提交给FDA。他们还将维持FDA 路易斯安那州分离株的季度结果，并将其与路易斯安那州结果进行准确性和 质量控制 在本赠款周期的头12个月，预期成果是： 每月购买、加工和检测80个肉类样品，并继续运送 用于NARMS测试。预期产出包括周转率减少 从沙门氏菌分离到将模式上传到PulseNet的时间以及抗生素的增加 沙门氏菌和弯曲杆菌的耐药性数据将与FDA的其他州的数据一起使用。 在五年的项目期间，预期产出是成功的零售肉类 路易斯安那州的食品安全计划和FDA NARMS的优质零售肉类监测数据， 除了从其他国家收到的数据外，还使用这些数据。这种高质量数据的增加可以帮助 影响抗菌药物使用政策。五年期的预期成果 包括：1）成功完成80种肉类的采购、加工和检测， 每月样品2)减少从沙门氏菌分离到检测的周转时间， 国家PFGE实验室和模式上传到PulseNet，这可能导致疫情增加 调查和解决零售肉制品中沙门氏菌的问题。3)的增加 将分析路易斯安那州特有的抗菌药物耐药性数据以了解趋势。