Biocatalyst Platform Technology for Enhancing Cometabolic Biodegradation

项目摘要/摘要 美国水资源受到有害有机化合物的污染， 对公众健康和安全构成严重和广泛的风险。有害有机化合物包括氯化溶剂， 碳氢化合物、消毒副产品、杀虫剂、多环芳烃（PAH）、多氯联苯（PCB）， 和其他异生物质（非天然存在的）有机化学品。由于这些化合物占275种化合物的大部分， 有毒物质和疾病登记署（ATSDR）排名的“高优先级”有害物质， 美国环境保护署（US EPA）和各州监管机构制定了雄心勃勃的处理方案， 这些危险的，往往是致癌物质的目标。除了增加患癌症的风险， 有害有机化合物的浓度已被证明会导致各种疾病，包括肝脏或肾脏 疾病、免疫功能障碍、神经系统紊乱和激素或生殖缺陷。 有害有机化合物的补救是困难和昂贵的。超级基金现场经理，市政当局和 全国各地的水供应商都要求更便宜，更有效的处理方案， 与现有的能源密集型和产生废物的传统技术相比，具体地说， 需要新的技术来将多种有害有机化合物的处理合并成简单的， 环境友好且易于使用的系统，尽可能减少处理单元。 该提案试图通过一种新的增强彗星技术来满足这一需求。相比于常规 物理或化学技术，如空气汽提和活性炭，这种新技术降低了危险的 有机化合物转化为无害的副产品，而不是产生浓缩的二次废物流。而且这 与化学或紫外线氧化相比，新技术可显著降低能源和维护成本。 这种新技术设计合理，可作为原位和非原位处理选项，在整个环境中提供可靠的性能。 在一系列动态操作条件下，可同时降解数百种有害有机化合物。 在该二期项目中，设计、建造、优化和测试了一个放大的中试工厂，以处理危险有机物 在一个高度污染的地方发现化合物该项目为新的 技术，同时让试点工厂进行一系列黄金标准压力测试，以获得关键的运营边界。 最后，该项目建立了详细的设计标准和必要的技术经济分析， 这项新技术，以解决各种迫切需要在超级基金网站，市政饮用水， 分散式处理、废水再利用和再循环以及农业和工业水处理部门。 该项目的成果是开发了一种首创的技术，用于降解 水中的有害有机化合物该项目的成功结果在解决以下问题方面具有重大前景： 使用现有技术无法有效处理的有害污染物，从而确保了巨大的价值 为子孙后代提供公共和私人环境管理。

Project Summary / Abstract The contamination of the water resources in the United States with hazardous organic compounds continues to pose serious and widespread risks to public health and safety. Hazardous organic compounds include chlorinated solvents, hydrocarbons, disinfection byproducts, pesticides, polyaromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), and other xenobiotic (not naturally occurring) organic chemicals. As these compounds comprise a majority of the 275 “high-priority” hazardous substances ranked by the Agency of Toxic Substances and Disease Registry (ATSDR), the United States Environmental Protection Agency (US EPA) and state regulatory agencies have set ambitious treatment goals for these dangerous and often carcinogenic substances. In addition to increased risks for cancer, very small concentrations of hazardous organic compounds have been proven to cause various illnesses including liver or kidney disease, immune dysfunction, nervous system disorders, and hormonal or reproductive defects. The remediation of hazardous organic compounds is difficult and costly. Superfund site managers, municipalities and water suppliers across the country are demanding less expensive and more effective treatment options for hazardous organic compounds than the existing suite of energy-intense and waste-producing conventional technologies. Specifically, there is a need for new technologies to consolidate the treatment of multiple hazardous organic compounds into simple, environmentally friendly, and easy-to-use systems with as minimal process units as possible. This proposal seeks to address this need through a novel enhanced cometabolism technology. In contrast to conventional physical or chemical technologies such as air stripping and activated carbon, this new technology degrades the hazardous organic compounds into harmless byproducts instead of producing a concentrated secondary waste stream. Moreover, this new technology offers significant reductions in energy and maintenance costs compared with chemical or UV oxidation. Flexibly designed as both an in-situ and ex-situ treatment option, this new technology offers reliable performance across a range of dynamic operating conditions to achieve simultaneous degradation of hundreds of hazardous organic compounds. In this Phase II project, a scaled-up pilot plant is designed, constructed, optimized, and tested to treat hazardous organic compounds at a high-profile contaminated site. This project establishes the long-term performance profile for the new technology while engaging the pilot plant in a series of gold-standard stress tests to obtain key operational boundaries. Ultimately, the project establishes the detailed design criteria and technoeconomic analysis necessary for implementing this new technology to address a variety of urgent needs across the Superfund site, municipal drinking water, decentralized treatment, wastewater reuse and recycle, and agricultural and industrial water treatment sectors. The outcome of this project is the development of a first-of-its-kind technology for degrading complex combinations of hazardous organic compounds in water. The successful result of this project holds significant promise in addressing harmful contaminants that are not effectively treatable using existing technologies, and thereby securing substantial value for public and private environmental stewardship for future generations.