Liver Injury and Iron Homeostasis in Health and Disease

健康和疾病中的肝损伤和铁稳态

• 批准号: nhmrc : GNT1118888
• 负责人: Prof V. Nathan Subramaniam
• 金额: $ 63.14万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/liver-injury-iron-health-disease/1347074
• 关键词: Liver; Injury; Iron; Homeostasis; Health

Iron disorders and liver disease are a significant burden on society, affecting many in the prime of their life. Disordered iron metabolism also plays a significant role in many disorders and diseases including cancers, neurodegenerative and iron overload disorders, and anaemia associated with chronic disease. My objective is to understand the molecules and mechanisms involved, and to develop strategies and reagents to diagnose, prevent and treat liver and iron-related disease.

铁失调和肝病是社会的重大负担，影响着许多年富力强的人。铁代谢紊乱在许多紊乱和疾病中也起着重要作用，包括癌症、神经退行性和铁超负荷疾病以及与慢性病相关的贫血。我的目标是了解所涉及的分子和机制，并开发诊断、预防和治疗肝脏和铁相关疾病的策略和试剂。