NUKIDs: Scientist Training Program in Kidney Disease

 描述(由申请人提供)：本提案是西北大学范伯格医学院肾脏研究培训国家研究服务奖的新申请。这一要求回应了对肾病学研究培训的迫切需求，在临床和基础学科提供了严格的指导和启发的研究经验。该计划基于目前基础、临床、翻译、公共卫生和健康服务研究方面的培训机会的优势，并在西北纪念医院和儿童卢里医院的成人和儿科肾脏病学部、移植医学部和西北校区的许多其他科室聘请了一批有才华的研究人员。这是第一次提出建议，正值范伯格医学院肾脏病部门和研究企业大幅和持续增长的时候。这一培训计划的长期、重要的目标是培养聪明、热情、训练有素、以学术为导向的医学博士、医学博士和博士，以追求肾脏疾病研究的事业。我们的计划将提供指导的“团队方法”，这将由拥有跨多个学科专业知识的临床和基础研究人员提供。这种方法将为学员提供在不断发展的科学环境中开发最具创新性、最成功和最重要的肾脏研究项目所需的基本技能，这在很大程度上取决于研究人员发展多学科合作的能力。培训补助金的具体目标是：1)发展 临床和基础研究科学家，他们最终将能够独立地进行假设驱动的研究，以满足我们目标患者群体的需求；2)为研究实习生提供津贴支持和保护时间；3)在成功开展与疾病病因、发病机制和结果相关的研究以及为所有形式的肾脏疾病患者和/或替代疗法的患者开发创新护理所必需的学科中，为基础和临床科学实习生提供严密的课堂和互动学习基础；5)建立持续的评估程序；6)通过共同指导过程提供对基础和临床研究的接触7)同时培训儿科和成人肾科医生，以提高对肾脏疾病的发生、发展和过渡的了解。

 DESCRIPTION (provided by applicant): This proposal is a new application of a National Research Service Award for Kidney Research Training at Northwestern University Feinberg School of Medicine. This request responds to the urgent need for Nephrology research training by providing rigorous mentored and inspired research experiences in both clinical and basic disciplines. The program builds on the strengths of current training opportunities in basic, clinical, translational, public health and health services research and engages a pool of talented investigators within the adult and pediatric divisions of Nephrology at Northwestern Memorial Hospital and Children's Lurie Hospital, the division of transplant medicine and numerous other Departments across the Northwestern campus. This first time proposal request comes at a time of substantial and sustained growth in the Divisions of Nephrology and the research enterprise of the Feinberg School of Medicine. The long-term, overriding, goal of this training program is to nurture bright, enthusiastic, well-trained, academically-oriented M.D.s, M.D.-PhD's and Ph.D's in pursuit of a career in Kidney Disease Investigation. Our program will provide a `team approach' to mentorship, which will be provided by both clinical and basic investigators who have expertise across multiple disciplines. This approach will provide trainees with essential skills needed to develop the most innovative, successful and significant kidney research programs in the ever- evolving scientific environment, which depends heavily on ability of investigators to develop multi-disciplinary collaborations. The specific objectives of the training grant are: 1) to develop clinical and basic research scientists, who will ultimately be capable of independently performing hypothesis-driven research that addresses the needs of our target patient population; 2) to provide stipend support and protected time for research trainees; 3) to provide both basic and clinical science trainees a rigorous base of classroom and interactive study in the disciplines necessary for successfully conducting research relevant to disease etiology, pathogenesis and outcomes and for the development of innovative care to patients with all forms of kidney disease and/or replacement therapy; 5) to establish an ongoing evaluation process; 6) to provide exposure to both basic and clinical research through a co-mentorship process 7) to train pediatric and adult nephrologists side-by-side to improve understanding of kidney disease initiation, progression and transition.