Administrative Core

行政核心

• 批准号: 10754081
• 负责人: SUSAN E. QUAGGIN
• 金额: $ 33.07万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10754081
• 关键词: Adopted; Collaborations; Communication; Communities; Development; Discipline; Drug Delivery Systems; Education; Educational workshop; Ensure; Evaluation; Event; Fostering; Funding; Goals; Healthcare; Information Centers; Infrastructure; International; Justice; Kidney; Lead; Leadership; Methods; Mission; Modeling; Monitor; Nanotechnology; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; Oncology; Principal Investigator; Procedures; Process; Publications; Recruitment Activity; Research; Research Personnel; Resource Allocation; Resource Development; Resource Sharing; Resources; Science; Scientist; Source; Structure; Students; Talents; Technology; Training; Training Activity; Universities; Work; biomedical resource; design; experience; high school; meetings; outreach; physical science; programs; summer student; symposium; synergism; technology development; timeline; training opportunity; web portal

PROJECT SUMMARY – ADMINISTRATIVE CORE The mission of the Administrative Core of the proposed O'Brien Northwestern University National Resource Center that will serve as the first Physical Sciences-Kidney Resource Center is two-fold: first, to create the infrastructure, processes and procedures that are required to guide the Center in accord with the Center framework; and second, to connect the Center with the broader NIDDK National Resource Network. The major goals of the Center's Administrative Core are to (1) Support transdisciplinary physical sciences in kidney research, training, and outreach; (2) Foster synergy and integration of the Center; (3) Support planning and evaluation activities; and (4) Expand participation and diversity of investigators in kidney research. The Center has adopted a multi-PI/PD leadership model for the Administrative, Biomedical, and Resource Development Cores, with leadership teams consisting of physical scientists and kidney researchers to provide top-down integration of physical sciences approaches and kidney research. The proposed administrative team of Drs. Quaggin (Principal Investigator/Director), Alfred George (Co-PI/PD/Co-Director), and Sheila Judge (Associate Director) brings extensive experience in developing effective strategies for management and training activities. The Administrative Core of the Northwestern University National Resource Center (NU-NRC) will fulfill its mission “to enable transformative kidney research through the application of physical sciences” with the following six Specific Aims: 1. Lead, manage, and integrate all aspects of the NU-NRC and ensure that Center resources are shared nationally. 2. Collaborate with the National Coordinating Center (NCC) and other NRCs to: (a) Prioritize external requests to maximize access to network resources; (b) Enhance national outreach and impact; and (c) Educate the community about kidney research. 3. Monitor emerging scientific technologies, methods, models, and concepts and facilitate their application to the needs of the national kidney research community. 4. Contribute to the expansion of the pool of kidney investigators. 5. Enhance the diversity of the Center and kidney research at Northwestern. 6. Develop and implement a Summer Student Enrichment program. The NU-NRC offers a robust infrastructure for providing established nanotechnology-based translational capabilities for drug delivery to kidney researchers through its Biomedical Resource Core and strong oversight mechanisms to foster new applications of physical science-based technologies through its Developmental Resource Core. In addition, the Center will leverage a well-established SciHigh program, a wide array of training opportunities, and pilot funding to expand and diversify the pool of talented kidney researchers and lower the barriers to research for early stage investigators. A well-defined set of Center metrics, milestones and timeline will aid ongoing evaluation of NU-NRC progress. Finally, NU-NRC leadership are poised to support the work of the O'Brien Kidney Consortium and maximize the value of resource centers across the consortium.

项目摘要——行政核心 拟议的奥布莱恩西北大学国家资源行政核心的使命 将作为第一个物理科学-肾脏资源中心的中心有两个目标：首先，创建 指导中心符合中心要求所需的基础设施、流程和程序 框架;其次，将该中心与更广泛的 NIDDK 国家资源网络连接起来。主要 该中心行政核心的目标是 (1) 支持肾脏跨学科物理科学 研究、培训和推广； （二）促进中心的协同和融合； (3) 支持规划和 评估活动； (4) 扩大肾脏研究研究者的参与度和多样性。中心 针对行政、生物医学和资源开发采用了多 PI/PD 领导模式 核心，由物理科学家和肾脏研究人员组成的领导团队提供自上而下的服务 物理科学方法和肾脏研究的整合。拟议的博士管理团队。 Quaggin（首席研究员/主任）、Alfred George（联合 PI/PD/联合主任）和 Sheila Judge（助理 董事）在制定有效的管理和培训活动策略方面拥有丰富的经验。 西北大学国家资源中心（NU-NRC）的行政核心将履行其职责 使命“通过应用物理科学实现变革性肾脏研究”，其目标如下 六个具体目标： 1. 领导、管理和整合 NU-NRC 的各个方面，并确保中心资源 是全国共享的。 2. 与国家协调中心 (NCC) 和其他 NRC 合作： (a) 对外部请求进行优先级排序，以最大限度地访问网络资源； (b) 加强国家宣传和影响； (c) 对社区进行有关肾脏研究的教育。 3. 监测新兴科学技术、方法、 模型和概念，并促进其应用以满足国家肾脏研究界的需求。 4. 为扩大肾脏研究人员库做出贡献。 5.增强中心和肾脏的多样性 西北大学的研究。 6. 制定并实施暑期学生强化计划。 NU-NRC 提供了强大的基础设施，用于提供基于纳米技术的转化 通过其生物医学资源核心和强有力的监督向肾脏研究人员提供药物的能力 通过其发展机制促进基于物理科学的技术的新应用 资源核心。此外，该中心将利用完善的 SciHigh 计划、广泛的培训 机会和试点资金，以扩大肾脏研究人才库并使其多样化，并降低 早期研究人员的研究障碍。一组明确定义的中心指标、里程碑和时间表 将有助于对 NU-NRC 进展进行持续评估。最后，NU-NRC 领导层准备支持 奥布莱恩肾脏联盟并最大限度地提高整个联盟资源中心的价值。