Novel Innate Immune Adjuvant for Avian Influenza. West Nile Virus, and ZIKA Vaccines
Novel Innate Immune Adjuvant for Avian Influenza. West Nile Virus, and ZIKA Vaccines
批准号:
9543270
负责人:
MICHAEL GALE
金额:
$330.8万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2017
资助国家:
美国
项目状态:
已结题
起止时间:
2017-09-30 至 2018-09-29
关键词:
AdjuvantAdjuvant StudyAntigensAvian InfluenzaAvian Influenza A VirusBird Flu vaccineDevelopmentDoseEmerging Communicable DiseasesFDA approvedFerretsFlavivirusFormulationGenesHumanIRF3 geneImmunologic AdjuvantsImmunologicsInfectionInfluenza A Virus, H5N1 SubtypeInvestigationInvestigational DrugsInvestigational New Drug ApplicationLeadLicensureMusNational Institute of Allergy and Infectious DiseaseNatural ImmunityPathogenicityPathway interactionsPharmaceutical ChemistryProgram DevelopmentSystemToxicologyTretinoinVaccine AdjuvantVaccinesVirus DiseasesWest Nile virusZika virus vaccineadaptive immune responsenovelpathogenprogramsresponsesmall moleculetranscription factorvaccine candidate
中文摘要
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英文摘要
The NIAID/DAIT Adjuvant Development Program supports the development of new candidate vaccine adjuvants through immunological characterization studies and lead compound optimization, up to and including IND-enabling studies, all towards licensure for human use. Adjuvants will be studied with currently licensed or new investigational vaccines to protect against infection by NIAID emerging and re-emerging infectious disease pathogens.
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Nonhuman Primate (NHP) Core Functional Genomics Laboratory for AIDS Vaccine Research and Development
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批准号:8751849
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财政年份:2013
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