2017 Microbial Population Biology Gordon Research Conference & Gordon Research Seminar
2017微生物种群生物学戈登研究会议
基本信息
- 批准号:9395217
- 负责人:
- 金额:$ 0.5万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2017
- 资助国家:美国
- 起止时间:2017-07-01 至 2018-06-30
- 项目状态:已结题
- 来源:
- 关键词:AddressAffectAntibiotic ResistanceBasic ScienceBiodiversityCommunicable DiseasesCountryDataDevelopmentDisciplineDiseaseEcologyEmerging Communicable DiseasesEvolutionFemaleGenetic EpistasisGenetic VariationGenomeGeographyGlobal WarmingGoalsHealthHumanImmune EvasionIndustryInternationalLeadLifeMaintenanceMentorsMethodsMicrobeModernizationNatural ResourcesNorth AmericaParticipantPlanet EarthPopulationPopulation BiologyPostdoctoral FellowRaceResearchResearch PersonnelScienceScientistStructureTechnologyTestingVirulenceWomanWorkarmcareercareer networkingfrontiergenome sequencinggraduate studentimprovedinsightlife historymeetingsmicrobialmicroorganism interactionnew technologynovelpathogenprofessorsymposiumtheorieswhole genomeyoung woman
项目摘要
Project Summary/Abstract
The richness of diversity found in our microbial world influences both human health and disease. The latter is
evident from immune evasion and the evolution and spread of antibiotic resistance among pathogens, which
threatens our ability to effectively treat infectious diseases. Since 1985 the Microbial Population Biology
Gordon Research Conference (GRC) has been the premier international meeting on the evolution and ecology
of microbial populations. Its long-term objective since 1985 is to improve our understanding of the evolutionary
forces that lead to the emergence and maintenance of genetic diversity within and between microbial species.
It typically attracts an outstanding and diverse group of scientists who work at the forefront of their discipline. In
addition an accompanying Gordon Research Seminar (GRS) for graduate students and postdoctoral fellows
precedes the conference since 2013. The specific goal of the 2017 GRC & GRS is to bring together thought
leaders from a spectrum of disciplines to present and discuss empirical data and theoretical concepts pertinent
to the adaptive evolution of not only microbes, but all other forms of life. The conference and seminar have the
following specific aims. Specific Aim 1: Interweave the findings of basic research done to develop and test
evolutionary theory with studies done to meet the modern day challenges of emerging infectious diseases, the
arms race of antibiotic resistance, sustainable use of natural resources, and global warming. This will be done
in nine non-overlapping sessions with the following topics: (i) Evolution and emergence of infectious diseases,
(ii) host-microbe coevolution, (iii) evolutionary consequences of epistasis, (iv) the evolution and spread of
antibiotic resistance, (v) antibiotic resistance in the field, (vi) genome evolution, (vii) new technologies lead to
new opportunities, (viii) ecological interactions of microbial populations, and (ix) the effect of spatial structure
on biodiversity. Specific Aim 2: Emphasize novel methods that are needed to better understand the evolution
of microbial pathogens and the interactions with each other and their host. Significant advances in technology
such as whole genome sequencing have accelerated and deepened our ability to explore the mechanisms of
microbial evolution and understand the diversity within microbial populations. One session in particular will
focus entirely on novel methods. Specific Aim 3: Highlight the work of younger scientists and enhance the
diversity of conference participants. Among the 33 speakers and discussion leaders confirmed so far, 15 are
female, 15 are still at the assistant professor level or equivalent, and 20 are from 12 countries other than the
US. It is expected that this great diversity in speakers will attract a greater ethnic and geographic diversity
among the participants than is typical for this GRC. Moreover, the high representation of young especially
female speakers will encourage young woman scientists to continue careers in science. Specific Aim 4:
Through a weekend-long GRS for graduate students and postdoctoral fellows, promote scientific interactions
among young researchers and offer mentoring and career advice.
项目总结/文摘
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Eva M. Top其他文献
Plasmids, a molecular cornerstone of antimicrobial resistance in the One Health era
质粒,一个在“同一健康”时代抗菌药物耐药性的分子基石
- DOI:
10.1038/s41579-023-00926-x - 发表时间:
2023-07-10 - 期刊:
- 影响因子:103.300
- 作者:
Salvador Castañeda-Barba;Eva M. Top;Thibault Stalder - 通讯作者:
Thibault Stalder
Plasmid-host adapatation through fitness cost ameriolation of a plasmid replication protein
通过质粒复制蛋白的适应度成本改善来适应质粒宿主
- DOI:
- 发表时间:
2014 - 期刊:
- 影响因子:0
- 作者:
Hirokazu Yano;Ktarznya Wegrzyn;Wesley Loftie-Eaton;Igor Konieczny;Eva M. Top - 通讯作者:
Eva M. Top
Determination of the mechanism of retrotransfer by mechanistic mathematical modeling
通过机械数学模型确定逆转录机制
- DOI:
- 发表时间:
1992 - 期刊:
- 影响因子:3.2
- 作者:
Eva M. Top;P. Vanrolleghem;M. Mergeay;Willy Verstraete - 通讯作者:
Willy Verstraete
複製開始タンパク質のフィットネスコストの改善を伴うプラスミドの宿主適応
质粒的宿主适应,提高了复制起始蛋白的适应性成本
- DOI:
- 发表时间:
2014 - 期刊:
- 影响因子:0
- 作者:
Hirokazu Yano;Ktarznya Wegrzyn;Wesley Loftie-Eaton;Igor Konieczny;Eva M. Top;矢野大和,Eva M Top - 通讯作者:
矢野大和,Eva M Top
The evolution of infectious transmission promotes the persistence of emmcr-1/em plasmids
感染传播的进化促进了 emmcr-1/em 质粒的持久性
- DOI:
10.1128/mbio.00442-23 - 发表时间:
2023-06-13 - 期刊:
- 影响因子:4.700
- 作者:
Jun Yang;Renjie Wu;Qiang Xia;Jingjing Yu;Ling-Xian Yi;Ying Huang;Meixin Deng;Wan-Yun He;Yuman Bai;Luchao Lv;Vincent Burrus;Chengzhen Wang;Jian-Hua Liu;Houra Merrikh;Eva M. Top - 通讯作者:
Eva M. Top
Eva M. Top的其他文献
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{{ truncateString('Eva M. Top', 18)}}的其他基金
COBRE: UID: PROJ 1: EVOLUTION OF ANTIBIOTIC RESISTANCE PLASMID HOST RANGE
COBRE:UID:项目 1:抗生素抗性质粒宿主范围的进化
- 批准号:
8359572 - 财政年份:2011
- 资助金额:
$ 0.5万 - 项目类别:
THE ORIGIN AND SPREAD OF MOSAIC PLASMIDS ENCODING MULTI-DRUG RESISTANCE(Research Supplement to Promote Diversity)
编码多药耐药性的镶嵌质粒的起源和传播(促进多样性的研究补充)
- 批准号:
10275435 - 财政年份:2010
- 资助金额:
$ 0.5万 - 项目类别:
Plasmid-Bacteria Coevolution Promotes the Spread of Antibiotic Resistance
质粒-细菌共同进化促进抗生素耐药性的传播
- 批准号:
10395990 - 财政年份:2010
- 资助金额:
$ 0.5万 - 项目类别:
Plasmid-Bacteria Coevolution Promotes the Spread of Antibiotic Resistance
质粒-细菌共同进化促进抗生素耐药性的传播
- 批准号:
9902314 - 财政年份:2010
- 资助金额:
$ 0.5万 - 项目类别:
COBRE: UID: PROJ 1: EVOLUTION OF ANTIBIOTIC RESISTANCE PLASMID HOST RANGE
COBRE:UID:项目 1:抗生素抗性质粒宿主范围的进化
- 批准号:
8167449 - 财政年份:2010
- 资助金额:
$ 0.5万 - 项目类别:
COBRE: UID: PROJ 1: EVOLUTION OF ANTIBIOTIC RESISTANCE PLASMID HOST RANGE
COBRE:UID:项目 1:抗生素抗性质粒宿主范围的进化
- 批准号:
7959524 - 财政年份:2009
- 资助金额:
$ 0.5万 - 项目类别:
COBRE: UID: PROJ 2: EVOLUTION OF ANTIBIOTIC RESISTANCE PLASMIDS
COBRE:UID:项目 2:抗生素抗性质粒的进化
- 批准号:
7720636 - 财政年份:2008
- 资助金额:
$ 0.5万 - 项目类别:
COBRE: UID: PROJ 2: EVOLUTION OF ANTIBIOTIC RESISTANCE PLASMIDS
COBRE:UID:项目 2:抗生素抗性质粒的进化
- 批准号:
7381297 - 财政年份:2006
- 资助金额:
$ 0.5万 - 项目类别:
COBRE: UID: PROJ 2: EVOLUTION OF ANTIBIOTIC RESISTANCE PLASMIDS
COBRE:UID:项目 2:抗生素抗性质粒的进化
- 批准号:
7170533 - 财政年份:2005
- 资助金额:
$ 0.5万 - 项目类别:
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