2017 Microbial Population Biology Gordon Research Conference & Gordon Research Seminar

2017微生物种群生物学戈登研究会议

• 批准号: 9395217
• 负责人: Eva M. Top
• 金额: $ 0.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-01 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9395217
• 关键词: Address; Affect; Antibiotic Resistance; Basic Science; Biodiversity; Communicable Diseases; Country; Data; Development; Discipline; Disease; Ecology; Emerging Communicable Diseases; Evolution; Female; Genetic Epistasis; Genetic Variation; Genome; Geography; Global Warming; Goals; Health; Human; Immune Evasion; Industry; International; Lead; Life; Maintenance; Mentors; Methods; Microbe; Modernization; Natural Resources; North America; Participant; Planet Earth; Population; Population Biology; Postdoctoral Fellow; Race; Research; Research Personnel; Science; Scientist; Structure; Technology; Testing; Virulence; Woman; Work; arm; career; career networking; frontier; genome sequencing; graduate student; improved; insight; life history; meetings; microbial; microorganism interaction; new technology; novel; pathogen; professor; symposium; theories; whole genome; young woman

Project Summary/Abstract The richness of diversity found in our microbial world influences both human health and disease. The latter is evident from immune evasion and the evolution and spread of antibiotic resistance among pathogens, which threatens our ability to effectively treat infectious diseases. Since 1985 the Microbial Population Biology Gordon Research Conference (GRC) has been the premier international meeting on the evolution and ecology of microbial populations. Its long-term objective since 1985 is to improve our understanding of the evolutionary forces that lead to the emergence and maintenance of genetic diversity within and between microbial species. It typically attracts an outstanding and diverse group of scientists who work at the forefront of their discipline. In addition an accompanying Gordon Research Seminar (GRS) for graduate students and postdoctoral fellows precedes the conference since 2013. The specific goal of the 2017 GRC & GRS is to bring together thought leaders from a spectrum of disciplines to present and discuss empirical data and theoretical concepts pertinent to the adaptive evolution of not only microbes, but all other forms of life. The conference and seminar have the following specific aims. Specific Aim 1: Interweave the findings of basic research done to develop and test evolutionary theory with studies done to meet the modern day challenges of emerging infectious diseases, the arms race of antibiotic resistance, sustainable use of natural resources, and global warming. This will be done in nine non-overlapping sessions with the following topics: (i) Evolution and emergence of infectious diseases, (ii) host-microbe coevolution, (iii) evolutionary consequences of epistasis, (iv) the evolution and spread of antibiotic resistance, (v) antibiotic resistance in the field, (vi) genome evolution, (vii) new technologies lead to new opportunities, (viii) ecological interactions of microbial populations, and (ix) the effect of spatial structure on biodiversity. Specific Aim 2: Emphasize novel methods that are needed to better understand the evolution of microbial pathogens and the interactions with each other and their host. Significant advances in technology such as whole genome sequencing have accelerated and deepened our ability to explore the mechanisms of microbial evolution and understand the diversity within microbial populations. One session in particular will focus entirely on novel methods. Specific Aim 3: Highlight the work of younger scientists and enhance the diversity of conference participants. Among the 33 speakers and discussion leaders confirmed so far, 15 are female, 15 are still at the assistant professor level or equivalent, and 20 are from 12 countries other than the US. It is expected that this great diversity in speakers will attract a greater ethnic and geographic diversity among the participants than is typical for this GRC. Moreover, the high representation of young especially female speakers will encourage young woman scientists to continue careers in science. Specific Aim 4: Through a weekend-long GRS for graduate students and postdoctoral fellows, promote scientific interactions among young researchers and offer mentoring and career advice.

项目总结/摘要 在我们的微生物世界中发现的丰富多样性影响着人类的健康和疾病。后者是 免疫逃避以及病原体抗生素耐药性的进化和传播是显而易见的，这 威胁到我们有效治疗传染病的能力。自1985年以来，微生物种群生物学 戈登研究会议（GRC）一直是关于进化和生态学的首要国际会议 微生物种群的数量。自1985年以来，它的长期目标是提高我们对进化的理解。 导致微生物物种内部和之间的遗传多样性的出现和维持的力量。 它通常吸引了一群杰出而多样化的科学家，他们在各自学科的前沿工作。在 此外，还为研究生和博士后研究员举办了戈登研究研讨会（GRS） 自2013年以来，会议。2017年GRC & GRS的具体目标是汇集思想 来自各个学科的领导者，介绍和讨论相关的经验数据和理论概念 不仅是微生物的适应性进化，还有所有其他形式的生命。会议和研讨会有 具体目标。具体目标1：将基础研究的结果交织在一起，以开发和测试 进化理论与研究所做的，以满足现代的挑战，新兴的传染病， 抗生素耐药性的军备竞赛、自然资源的可持续利用和全球变暖。为此将 （一）传染病的演变和出现， (ii)宿主-微生物协同进化，（iii）上位性的进化后果，（iv） 抗生素耐药性，（五）抗生素耐药性的领域，（六）基因组进化，（七）新技术导致 新的机会，（viii）微生物种群的生态相互作用，（ix）空间结构的影响 关于生物多样性。具体目标2：强调更好地理解进化所需的新方法 微生物病原体之间的相互作用以及它们与宿主的相互作用。技术的重大进步 例如全基因组测序，加速并加深了我们探索基因突变机制的能力。 微生物进化和了解微生物种群的多样性。特别是一次会议将 专注于新的方法。具体目标3：突出青年科学家的工作， 与会者的多样性。在迄今确认的33位发言人和讨论负责人中， 15人仍为助理教授或同等学历，20人来自12个国家， 我们人们预计，这种发言者的巨大多样性将吸引更大的种族和地理多样性 在参与者中，比这个GRC的典型情况要多。此外，年轻人特别是 女发言人将鼓励年轻女科学家继续从事科学事业。具体目标4： 通过为期一周的研究生和博士后研究员GRS，促进科学互动 并提供指导和职业建议。