Comparison of Substance Use Screeners in Assessing Prescription Drug Abuse and Other Illicit Drug Use among Pregnant Women

药物使用筛查仪在评估孕妇处方药滥用和其他非法药物使用方面的比较

• 批准号: 9762358
• 负责人: Victoria Hope Coleman-Cowger
• 金额: $ 16.9万
• 依托单位: THE EMMES COMPANY, LLC
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-15 至 2020-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9762358
• 关键词: Comparison; Substance; Use; Screeners; Assessing

Project Summary Over the last 3 decades, use of prescription drugs has increased by more than 60%, and prevalence of prescription drug use among pregnant women is currently estimated around 50%. Children born to women who abuse prescription medications are more likely to be born with neonatal abstinence syndrome, the incidence of which has doubled in the past 5 years. Recent national survey data show that the rate of current illicit drug use is 14.6% among pregnant adolescents, 8.6% among young adults, and 3.2% among adults. The first step in identifying both prescription drug abuse and illicit drug use during pregnancy is screening; however, no specific substance use screener has been recommended for use with pregnant women to identify illicit or prescription drug use. The proposed study will compare and validate three existing substance use screeners - 4 P's Plus, NIDA Quick Screen, and the Substance Use Risk Profile-Pregnancy scale - among at least 500 pregnant women in all three trimesters of pregnancy presenting to two primary care clinics in Baltimore over 1 year. Specific aims are to: (1) conduct validity analyses to determine sensitivity, specificity, usability, and how each scale compares to the others and to the gold standard of urine drug testing in identifying prescription and illicit drug use; (2) determine the impact of clinic population variables (age, race, trimester of pregnancy) on validity of the three substance use screeners; and (3) assess birth outcomes (birth weight, gestational age, head circumference, and NICU admissions) associated with the most widely used prescription drug. The end goal of the study is to determine which screening tool(s) is most effective in identifying prescription drug abuse and illicit drug use among pregnant women, utilizing urine drug testing as the gold standard to designate use and electronic medical records (EMR) as a supplement to identify prescribed drugs. Aim 3 was added to capture the important and relevant associations between the most widely used prescription drug and birth outcomes.

项目概要 过去 3 年来，处方药的使用量增加了 60% 以上，并且 目前估计孕妇使用处方药的比例约为 50%。下列妇女所生的孩子 滥用处方药更有可能出生时患有新生儿戒断综合症， 过去5年翻了一番。最近的全国调查数据显示，目前非法药物使用率 怀孕青少年中这一比例为 14.6%，青壮年中为 8.6%，成人中为 3.2%。第一步 筛查是识别妊娠期间处方药滥用和非法药物使用的过程；但没有具体 建议孕妇使用物质使用筛查仪来识别非法或处方药物 药物使用。拟议的研究将比较和验证三种现有的物质使用筛查仪 - 4 P's Plus、 NIDA 快速筛查和药物使用风险概况 - 怀孕量表 - 至少 500 名孕妇 一年多来巴尔的摩两家初级保健诊所就诊的所有怀孕三个三个月的妇女。 具体目标是：(1) 进行有效性分析以确定敏感性、特异性、可用性以及每个指标的作用 该量表与其他量表以及尿液药物检测在识别处方药和非法药物方面的黄金标准进行了比较 吸毒； (2) 确定临床人群变量（年龄、种族、妊娠三个月）对有效性的影响 三个物质使用筛选器中的哪一个； (3) 评估出生结果（出生体重、胎龄、头围） 周长和 NICU 入院率）与最广泛使用的处方药相关。最终目标为 该研究旨在确定哪种筛查工具在识别处方药滥用和 孕妇非法药物使用，利用尿液药物检测作为指定使用和使用的金标准 电子病历 (EMR) 作为识别处方药物的补充。添加了目标 3 来捕捉 最广泛使用的处方药与出生结果之间的重要且相关的关联。

项目成果

Patient Perceptions of Three Substance Use Screening Tools for Use During Pregnancy.

患者对怀孕期间使用的三种药物使用筛查工具的看法。

• DOI: 10.1007/s10995-022-03442-1
• 发表时间: 2022
• 期刊: Maternal and child health journal
• 影响因子: 2.3
• 作者: Trocin,KathleenE;Oga,EmmanuelA;Mulatya,Caroline;Mark,KatrinaS;Coleman-Cowger,VictoriaH
• 通讯作者: Coleman-Cowger,VictoriaH

Prevalence and associated birth outcomes of co-use of Cannabis and tobacco cigarettes during pregnancy.

• DOI: 10.1016/j.ntt.2018.06.001
• 发表时间: 2018-07
• 期刊: Neurotoxicology and teratology
• 影响因子: 2.9
• 作者: Coleman-Cowger VH;Oga EA;Peters EN;Mark K
• 通讯作者: Mark K

Prenatal Substance Use and Perceptions of Parent and Partner Use Using the 4P's Plus Screener.

使用 4Ps Plus 筛查仪了解产前药物使用情况以及父母和伴侣使用药物的看法。

• DOI: 10.1007/s10995-018-2647-2
• 发表时间: 2019
• 期刊: Maternal and child health journal
• 影响因子: 2.3
• 作者: Oga,EmmanuelA;Peters,EricaN;Mark,Katrina;Trocin,Kathleen;Coleman-Cowger,VictoriaH
• 通讯作者: Coleman-Cowger,VictoriaH