AHA Basic Cardiovascular Sciences Council (BCVS), 2017 Scientific Sessions: Pathways to Cardiovascular Therapeutics

项目摘要/摘要 我们请求为2017年夏季基础心血管科学研讨会提供支持 美国心脏协会理事会(BCVS)。AHA BCVS理事会是领先的 国际心血管科学家组织。我们的年度科学会议是 AHA BCVS理事会十多年来的标志性年度科学会议，并已 自2005年以来一直得到国家心肺血液研究所(NHLBI)的部分支持。正在进行中 来自NHLBI的支持帮助将这次会议培养成了心血管领域的“去”会议 生物学和疾病。今年，大会将于2017年7月10日至13日在俄勒冈州波特兰举行，时间为 市中心的波特兰希尔顿酒店和行政大楼。该项目的联合主席是迈克尔·S·麦克唐纳博士。 Kapiloff(迈阿密大学)，Rong Tian(华盛顿大学，西雅图)和Jennifer E.Van Eyk (锡达斯-西奈医疗中心)一直与BCVS主席和他们的 计划委员会计划和执行这一重要的会议。该计划联合主席有 组织国内和国际会议的丰富经验，以及他们的科学专长 涵盖广泛的学科，例如分子信号、线粒体生物学和新陈代谢， 蛋白质组学和大数据。 这次会议的具体目的是：(1)展示基本和翻译的前沿 心血管科学；(2)加强不同地域研究人员之间的合作 地点、学科和职业阶段；(3)催化新的想法/方向；以及(4)激发下一个 一代心血管科学研究人员。计划中的议程代表着一个令人兴奋的， 快节奏会议，为期4天，30场会议，包括Calum MacRae博士的主题演讲， 2016年AHA“一个勇敢的想法”奖的获得者。年轻的心血管科学家将成为 通过每次会议的特邀演讲和海报演示突出显示。初级科学家将成为 从会议主题中提交的摘要中挑选发言。另外，整个上午， 会议的主要内容是举办一项“青年调查员奖”的角逐活动，为 面向具有杰出科学和未来潜力的高级博士后和初级教职员工展示他们的 工作。2017年大会将有30%以上的女性教职员工，这反映了我们对 改善受邀演讲者的性别平衡。此外，一次早餐会的重点是 计划为女科学家提供职业发展和指导。最后，从一个新的方面来看 会议将有3个新兵训练营参加，重点是：1)实施新出现的‘OMIC技术’ 基础科学，二)开发大数据和数据库，为基础科学研究提供信息，三)一 一对一指导，以加强对BCVS与会者自己的科学项目的实施。这个 本申请所要求的预算约占会议预算总额的7%。类似 与前几年相比，此应用程序的支持将仅用于15个心血管疾病 外展奖和15个青年调查员旅行奖。

Project Summary/Abstract We request support for the Annual Summer 2017 Symposium of the Basic Cardiovascular Sciences Council (BCVS) of the American Heart Association (AHA). AHA BCVS Council is the leading international organization for cardiovascular scientists. Our annual scientific conference serves as the hallmark annual scientific conference for the AHA BCVS Council for more than a decade and has been partially supported by the National Heart, Lung, Blood Institute (NHLBI) since 2005. Ongoing support from NHLBI has helped foster this meeting into the “go to” conference for cardiovascular biology and disease. This year, the conference will be held July 10-13, 2017, in Portland, Oregon at the downtown Hilton Portland and Executive Tower. The program co-chairs are Drs. Michael S. Kapiloff (University of Miami), Rong Tian (University of Washington, Seattle) and Jennifer E. Van Eyk (Cedars-Sinai Medical Center) who have been working closely with the BCVS Chair and their Program Committee to plan and execute this important conference. The program co-chairs have extensive experience organizing national and international conferences, and their scientific expertise covers a broad range of disciplines, e.g. molecular signaling, mitochondrial biology and metabolism, proteomics and big data. The Specific Aims for this conference are to: (1) Showcase the frontiers of basic and translational cardiovascular science; (2) Enhance collaborations among investigators with diverse geographic locations, disciplines and career stages; (3) Catalyze new ideas/directions; and (4) Inspire the next generation of researchers in cardiovascular science. The planned agenda represents an exciting, fast-paced meeting with 30 sessions over 4 days, including a Keynote lecture by Dr. Calum MacRae, recipient of the 2016 AHA “One Brave Idea” award. Young cardiovascular scientists will be highlighted through invited talks at each session and poster presentations. Junior scientists will be selected to speak from abstracts submitted within their session topics. In addition, an entire morning of the meeting will be devoted to a competition for the “Young Investigator Award,” giving opportunity for senior postdocs and junior faculty with outstanding science and future potential to present their work. The 2017 conference will have more than 30% women faculty, reflecting our commitment to improve gender balance among invited speakers. Moreover, one breakfast session focusing on the career development and mentorship for women scientists is planned. Finally, a novel aspect of the meeting will be 3 boot camps focused on i) implementation of emerging `Omic technologies targeting basic science, ii) exploitation of big data and databases to inform basic science studies and iii) one- on-one mentoring to enhance implementation into BCVS attendee's own science programs. The budget requested in this application constitutes approximately 7% of the total meeting budget. Similar to previous years, support from this application will be exclusively used towards 15 Cardiovascular Outreach Awards and 15 Young Investigator Travel Awards.