Visual Sciences Training Program

视觉科学培训计划

• 批准号: 9280013
• 负责人: Krzysztof Palczewski
• 金额: $ 18.75万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-06-01 至 2022-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9280013
• 关键词: Training Programs; vision science

Twenty-five faculty affiliated with the Visual Sciences Research Center (VSRC) at Case Western Reserve University (CWRU) seek renewed support for the Visual Sciences Training Program (VSTP). The faculty comprises a multi-disciplinary vision sciences research community of basic and clinical scientists encompassing the Departments of, Epidemiology and Biostatistics, Medicine, Molecular Biology & Microbiology, , Ophthalmology & Visual Sciences (UH), Ophthalmology (CCLCM), Pathology, Pharmacology, Physiology & Biophysics, and Systems Biology & Bioinformatics. This group’s capabilities and productivity in the field of vision research has led to its support as a priority focus in strategic planning at Case Western Reserve University. The momentum associated with the recent expansion of the NEI Core grant-supported Visual Sciences Research Center and the awards of two R24 and U01 grants from the NEI have bolstered a critical mass of vision scientists with extramural support for their research. This atmosphere affords an ideal training opportunity for vision scientists. The Visual Sciences Research Center and collaborative research of its participating faculty provide an overall framework for the Visual Sciences Training Program. In addition, as vision research has expanded at CWRU, there has been a natural evolution of research/training groups that have distinct identities but also considerable overlap. This T32 Institutional Training Grant renewal application is organized according to four major vision science research themes: (a) Retinal Development and Function; (b) Retinal Disorders: Diabetic Retinopathy (DR) and Age-related Macular Degeneration (AMD); (c) Biochemistry, Cell Biology, Immunology of Eye Diseases; and (d) Genetics, Physiology, and Epidemiology of Eye Diseases. These themes, involving groups of collaborating faculty, students and postdoctoral fellows, provide a natural way to organize the training program. In addition, there is a strong translational theme focused on therapeutic discovery that is an important aspect of all four research clusters. Continued support is requested for five pre-doctoral student positions and one post-doctoral position in all years. The rich research environment for vision science serves to attract trainees of the highest potential. Students receive training in Ph.D. program-specific, vision research theme-specific, and laboratory-based settings. Collectively, this approach ensures that our trainees are equipped with the broad interdisciplinary knowledge and technical skills needed to pursue biologically and clinically relevant research questions. The training program is supported by the resources of the faculty with vision science research expertise and their collaborators, by the Core Modules of the Visual Science Research Center, and by the broader resources of Case Western Reserve University, University Hospitals of Cleveland, the Cleveland Clinic Lerner Research and Cole Eye Institutes, and the Louis Stokes Cleveland VA Medical Research Center.

凯斯西储大学视觉科学研究中心 (VSRC) 的 25 名教员 大学（CWRU）寻求对视觉科学培训计划（VSTP）的新支持。师资队伍 由基础科学家和临床科学家组成的多学科视觉科学研究团体 包括流行病学和生物统计学、医学、分子生物学和 微生物学、眼科与视觉科学 (UH)、眼科 (CCLCM)、病理学、药理学、 生理学与生物物理学，以及系统生物学与生物信息学。该团队的能力和生产力 视觉领域研究使其成为 Case Western 战略规划的优先重点 储备大学。与近期 NEI 核心赠款支持的扩张相关的势头 视觉科学研究中心以及 NEI 的两项 R24 和 U01 资助，增强了 为他们的研究提供校外支持的关键数量的视觉科学家。这种氛围提供了理想的 视觉科学家的培训机会。视觉科学研究中心和合作研究 其参与的教师为视觉科学培训计划提供了总体框架。此外，如 CWRU 的视觉研究得到了扩展，研究/培训小组自然演变， 具有不同的身份，但也有相当大的重叠。此 T32 机构培训补助金续签申请 根据四个主要视觉科学研究主题组织： (a) 视网膜发育和功能； (b) 视网膜疾病：糖尿病性视网膜病（DR）和年龄相关性黄斑变性（AMD）； (三) 生物化学、细胞生物学、眼病免疫学； (d) 遗传学、生理学和流行病学 眼部疾病。这些主题涉及教师、学生和博士后研究员的合作团体， 提供一种自然的方式来组织培训计划。此外，还有一个强烈的翻译主题 专注于治疗发现，这是所有四个研究集群的一个重要方面。持续支持是 全年要求设立5个博士前生岗位和1个博士后岗位。丰富的研究 视觉科学的环境有助于吸引最具潜力的学员。学生接受培训 博士特定项目、特定视觉研究主题和基于实验室的设置。总的来说，这 方法确保我们的学员具备广泛的跨学科知识和技术技能 需要追求生物学和临床相关的研究问题。该培训计划由以下机构支持 具有视觉科学研究专业知识的教师及其合作者的资源，按核心模块划分 视觉科学研究中心以及凯斯西储大学更广泛的资源， 克利夫兰大学医院、克利夫兰诊所勒纳研究中心和科尔眼科研究所以及路易斯 斯托克斯克利夫兰退伍军人医学研究中心。