Visual Sciences Training Program

视觉科学培训计划

• 批准号: 9280013
• 负责人: Krzysztof Palczewski
• 金额: $ 18.75万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-06-01 至 2022-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9280013
• 关键词: Training Programs; vision science

Twenty-five faculty affiliated with the Visual Sciences Research Center (VSRC) at Case Western Reserve University (CWRU) seek renewed support for the Visual Sciences Training Program (VSTP). The faculty comprises a multi-disciplinary vision sciences research community of basic and clinical scientists encompassing the Departments of, Epidemiology and Biostatistics, Medicine, Molecular Biology & Microbiology, , Ophthalmology & Visual Sciences (UH), Ophthalmology (CCLCM), Pathology, Pharmacology, Physiology & Biophysics, and Systems Biology & Bioinformatics. This group’s capabilities and productivity in the field of vision research has led to its support as a priority focus in strategic planning at Case Western Reserve University. The momentum associated with the recent expansion of the NEI Core grant-supported Visual Sciences Research Center and the awards of two R24 and U01 grants from the NEI have bolstered a critical mass of vision scientists with extramural support for their research. This atmosphere affords an ideal training opportunity for vision scientists. The Visual Sciences Research Center and collaborative research of its participating faculty provide an overall framework for the Visual Sciences Training Program. In addition, as vision research has expanded at CWRU, there has been a natural evolution of research/training groups that have distinct identities but also considerable overlap. This T32 Institutional Training Grant renewal application is organized according to four major vision science research themes: (a) Retinal Development and Function; (b) Retinal Disorders: Diabetic Retinopathy (DR) and Age-related Macular Degeneration (AMD); (c) Biochemistry, Cell Biology, Immunology of Eye Diseases; and (d) Genetics, Physiology, and Epidemiology of Eye Diseases. These themes, involving groups of collaborating faculty, students and postdoctoral fellows, provide a natural way to organize the training program. In addition, there is a strong translational theme focused on therapeutic discovery that is an important aspect of all four research clusters. Continued support is requested for five pre-doctoral student positions and one post-doctoral position in all years. The rich research environment for vision science serves to attract trainees of the highest potential. Students receive training in Ph.D. program-specific, vision research theme-specific, and laboratory-based settings. Collectively, this approach ensures that our trainees are equipped with the broad interdisciplinary knowledge and technical skills needed to pursue biologically and clinically relevant research questions. The training program is supported by the resources of the faculty with vision science research expertise and their collaborators, by the Core Modules of the Visual Science Research Center, and by the broader resources of Case Western Reserve University, University Hospitals of Cleveland, the Cleveland Clinic Lerner Research and Cole Eye Institutes, and the Louis Stokes Cleveland VA Medical Research Center.

25名附属于凯斯西储视觉科学研究中心(VSRC)的教员 CWRU)为视觉科学培训计划(VSTP)寻求新的支持。教职员工 由基础和临床科学家组成的多学科视觉科学研究社区 包括流行病学和生物统计学、医学、分子生物学和 微生物学、眼科学与视觉科学(UH)、眼科学(CCLCM)、病理学、药理学、 生理学与生物物理学、系统生物学与生物信息学。该团队在以下方面的能力和生产力 视觉研究领域的支持使其成为凯斯韦斯特公司战略规划的优先重点 后备大学。与最近扩大NEI核心赠款相关的势头 视觉科学研究中心和来自NEI的两个R24和U01奖项支持了 为他们的研究提供外部支持的视觉科学家的临界质量。这种氛围提供了一种理想的 为视觉科学家提供培训机会。视觉科学研究中心与合作研究 它的参与教员为视觉科学培训计划提供了一个总体框架。此外，AS 视觉研究在CWRU得到了扩展，研究/培训小组的自然演变 有不同的身份，但也有相当大的重叠。这份T32院校培训补助金续期申请 是根据四个主要的视觉科学研究主题组织的：(A)视网膜的发展和功能； (B)视网膜疾病：糖尿病视网膜病变(DR)和老年性黄斑变性(AMD)； 生物化学、细胞生物学、眼科疾病免疫学；以及(D)青光眼的遗传学、生理学和流行病学 眼科疾病。这些主题涉及合作教职员工、学生和博士后研究员团体， 提供一种自然的方式来组织培训计划。此外，还有一个很强的翻译主题 专注于治疗发现，这是所有四个研究集群的一个重要方面。持续的支持是 申请5个博士后职位和1个博士后职位。丰富的研究成果 视觉科学环境服务于吸引最具潜力的学员。学生接受培训 特定于博士项目，特定于视觉研究主题，以实验室为基础的环境。总而言之，这 该方法确保我们的受训人员具备广泛的跨学科知识和技术技能 需要寻求与生物学和临床相关的研究问题。该培训计划由 拥有视觉科学研究专长的教员及其合作者的资源，由核心模块提供 视觉科学研究中心，以及凯斯西储大学更广泛的资源， 克利夫兰大学医院，克利夫兰临床勒纳研究和科尔眼科研究所，以及路易斯 斯托克斯·克利夫兰退伍军人医学研究中心。