Mechanisms of sensorineural hearing loss: secreted factors
Mechanisms of sensorineural hearing loss: secreted factors
批准号:
9352311
负责人:
Konstantina M Stankovic
金额:
$42.5万
依托单位国家:
美国
项目类别:
财政年份:
2016
资助国家:
美国
项目状态:
已结题
起止时间:
2016-09-13 至 2021-08-31
关键词:
Acoustic NerveAcoustic NeuromaAcoustic TraumaAcuteAffectAminoglycosidesAnatomyAnimal ModelAnimalsApoptosisAudiometryAuditoryAutopsyBiochemicalCaviaChronicClinicalComputersCore FacilityCustomDataEarEducational process of instructingEnzyme-Linked Immunosorbent AssayEquilibriumEventEyeFDA approvedFGF2 geneFacial paralysisFloorFunctional disorderFutureGene TargetingGenerationsHair CellsHearingHistologicHospital ReferralsHospitalsHumanImmuneImmunohistochemistryIn VitroInternetIntracranial NeoplasmsIpsilateralLaboratoriesLightLinear RegressionsLiquid substanceMassachusettsMeasurementMeasuresMechanicsMediatingMediator of activation proteinMicroRNAsModelingMolecularMusNerve compression syndromeNeuronsNon-MalignantOuter Hair CellsPathologyPathway interactionsPatient CarePatientsPersonal ComputersPharmaceutical PreparationsPharmacologyPharmacotherapyPhysiologicalPilot ProjectsProteinsRadiology SpecialtyResearchResourcesReverse Transcriptase Polymerase Chain ReactionRoleSamplingSchwann CellsSecondary toSensorineural Hearing LossSeveritiesSignal TransductionSynapsesSystemTNF geneTemporal bone structureTestingTimeTinnitusToxic effectTranslationsVestibular NerveViralViral VectorWorkanimal careclinical Diagnosisclinically relevantdeafnessdesignexperimental studyhearing impairmentin vivoinsightmedical schoolsmemberneurophysiologynovelotoacoustic emissionototoxicitypreventsquare foottargeted treatmenttumor necrosis factor-alpha inhibitor
中文摘要
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英文摘要
Resources
Facilities
The Eaton-Peabody Laboratories (EPL) at the Massachusetts Eye and Ear Infirmary (MEEI) occupies ~10,000
sq ft, 2500 sq ft and 2000 sq ft on floors 4, 6 and 3, respectively. The laboratory is fully equipped for
neurophysiological, anatomic, histologic, immunohistochemical and molecular studies.
Clinical
The Masschusetts Eye and Ear Infirmary is a tertiary referral hospital and a teaching affiliate of Harvard
Medical School. The hospital has state of the art facilities for care of patients with hearing loss.
Animal
There is a fully equipped animal care facility at MEEI, which includes two animal rooms (~400 sq. ft. each)
reserved for use by members of EPL. The facility also includes rooms for acute and chronic animals.
Computer
Personal computers with internet access are available throughout the EPL. Computer facilities are maintained
by full time computer programmer and systems analysts.
Office
The P.I. has a 200 sq ft office at MEEI adjacent to her dedicated laboratory space of ~1000 sq ft.
Other
The P.I. has access to the viral core facility at Massachusetts Eye and Ear. The core facility is fully equipped
for customized viral vector design.
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会议论文
Targeting HMGB1 to improve hearing andenhance therapy for Vestibular Schwannomas
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批准号:10734153
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项目类别:
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资助金额:$45.96万
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财政年份:2023
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负责人:Konstantina M Stankovic
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依托单位:
Mechanisms of sensorineural hearing loss: secreted factors
-
批准号:9759905
-
项目类别:
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资助金额:$42.5万
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财政年份:2016
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负责人:Konstantina M Stankovic
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依托单位:
Mechanisms of sensorineural hearing loss: secreted factors
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批准号:9221084
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项目类别:
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资助金额:$42.44万
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财政年份:2016
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负责人:Konstantina M Stankovic
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依托单位:
Mechanisms of sensorineural hearing loss: secreted factors
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批准号:10514157
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项目类别:
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资助金额:$18.11万
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财政年份:2016
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负责人:Konstantina M Stankovic
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依托单位:
Understanding Noise-Induced Delayed Primary Degeneration of the Auditory Nerve
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批准号:8385567
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项目类别:
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资助金额:$23.5万
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财政年份:2009
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负责人:Konstantina M Stankovic
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依托单位:
Understanding Noise-Induced Delayed Primary Degeneration of the Auditory Nerve
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批准号:8197270
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项目类别:
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资助金额:$23.5万
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财政年份:2009
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负责人:Konstantina M Stankovic
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依托单位:
Understanding Noise-Induced Delayed Primary Degeneration of the Auditory Nerve
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批准号:8586254
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项目类别:
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资助金额:$23.5万
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财政年份:2009
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负责人:Konstantina M Stankovic
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依托单位:
Understanding Noise-Induced Delayed Primary Degeneration of the Auditory Nerve
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批准号:7772041
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项目类别:
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资助金额:$23.5万
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财政年份:2009
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负责人:Konstantina M Stankovic
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依托单位:
Understanding Noise-Induced Delayed Primary Degeneration of the Auditory Nerve
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批准号:8002074
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项目类别:
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资助金额:$23.5万
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财政年份:2009
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负责人:Konstantina M Stankovic
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依托单位:
海外基金