Mechanisms of sensorineural hearing loss: secreted factors
Mechanisms of sensorineural hearing loss: secreted factors
批准号:
9221084
负责人:
Konstantina M Stankovic
金额:
$42.44万
依托单位国家:
美国
项目类别:
财政年份:
2016
资助国家:
美国
项目状态:
已结题
起止时间:
2016-09-13 至 2021-08-31
关键词:
Acoustic NerveAcoustic NeuromaAcoustic TraumaAcuteAffectAminoglycosidesAnatomyAnimal ModelAnimalsApoptosisAudiometryAuditoryCaviaChronicClinicalComputersConditioned Culture MediaCore FacilityDataDiagnosisEarEducational process of instructingEnzyme-Linked Immunosorbent AssayEquilibriumEventEyeFDA approvedFGF2 geneFacial paralysisFloorFunctional disorderFutureGene TargetingGenerationsHair CellsHearingHistologicHospital ReferralsHospitalsHumanImmuneImmunohistochemistryIn VitroInternetIntracranial NeoplasmsIpsilateralLaboratoriesLightLinear RegressionsLiquid substanceMassachusettsMeasurementMeasuresMechanicsMediatingMediator of activation proteinMicroRNAsModelingMolecularMusNerve compression syndromeNeuronsNon-MalignantOuter Hair CellsPathologyPathway interactionsPatient CarePatientsPersonal ComputersPharmaceutical PreparationsPharmacotherapyPilot ProjectsProteinsResearchResourcesReverse Transcriptase Polymerase Chain ReactionRoleSamplingSchwann CellsSecondary toSensorineural Hearing LossSeveritiesSignal TransductionSynapsesSystemTNF geneTemporal bone structureTestingTimeTinnitusToxic effectTranslationsVestibular NerveViralViral VectorWorkanimal careclinically relevantdeafnessdesignhearing impairmentin vivoinhibitor/antagonistinsightmedical schoolsmemberneurophysiologynovelotoacoustic emissionototoxicitypreventresearch studysquare foottargeted treatmenttumor
中文摘要
资源
设施
位于马萨诸塞州眼耳医院(MEEI)的伊顿-皮博迪实验室(EPL)占地约10,000
第四、六及三层分别为2500平方呎、2000平方呎及2000平方呎。实验室设备齐全,
神经生理学、解剖学、组织学、免疫组织化学和分子研究。
临床
马萨诸塞州眼耳医院是一家三级转诊医院,也是哈佛大学的教学附属医院
医学院该医院拥有最先进的设施,用于照顾听力损失患者。
动物
MEEI有一个设备齐全的动物护理设施,包括两个动物房(约400平方米)。英尺每个)
仅供EPL成员使用。该设施还包括急性和慢性动物的房间。
计算机
整个EPL都提供可上网的个人电脑。计算机设施得到维护
全职计算机程序员和系统分析师。
办公室
私家侦探在MEEI有一个200平方英尺的办公室,毗邻她的专用实验室空间约1000平方英尺。
其他
私家侦探能进入马萨诸塞州眼耳中心的病毒核心设施核心设施配套齐全
用于定制病毒载体设计。
英文摘要
Resources
Facilities
The Eaton-Peabody Laboratories (EPL) at the Massachusetts Eye and Ear Infirmary (MEEI) occupies ~10,000
sq ft, 2500 sq ft and 2000 sq ft on floors 4, 6 and 3, respectively. The laboratory is fully equipped for
neurophysiological, anatomic, histologic, immunohistochemical and molecular studies.
Clinical
The Masschusetts Eye and Ear Infirmary is a tertiary referral hospital and a teaching affiliate of Harvard
Medical School. The hospital has state of the art facilities for care of patients with hearing loss.
Animal
There is a fully equipped animal care facility at MEEI, which includes two animal rooms (~400 sq. ft. each)
reserved for use by members of EPL. The facility also includes rooms for acute and chronic animals.
Computer
Personal computers with internet access are available throughout the EPL. Computer facilities are maintained
by full time computer programmer and systems analysts.
Office
The P.I. has a 200 sq ft office at MEEI adjacent to her dedicated laboratory space of ~1000 sq ft.
Other
The P.I. has access to the viral core facility at Massachusetts Eye and Ear. The core facility is fully equipped
for customized viral vector design.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Targeting HMGB1 to improve hearing andenhance therapy for Vestibular Schwannomas
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批准号:10734153
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项目类别:
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资助金额:$45.96万
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财政年份:2023
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负责人:Konstantina M Stankovic
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依托单位:
Mechanisms of sensorineural hearing loss: secreted factors
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批准号:9759905
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项目类别:
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资助金额:$42.5万
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负责人:Konstantina M Stankovic
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依托单位:
Mechanisms of sensorineural hearing loss: secreted factors
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资助金额:$42.5万
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财政年份:2016
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依托单位:
Mechanisms of sensorineural hearing loss: secreted factors
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批准号:8197270
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批准号:8586254
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资助金额:$23.5万
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Understanding Noise-Induced Delayed Primary Degeneration of the Auditory Nerve
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批准号:7772041
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资助金额:$23.5万
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负责人:Konstantina M Stankovic
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资助金额:$23.5万
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依托单位:
海外基金