Intervention to increase access to PEP to prevent HIV infection among Black MSM

增加获得 PEP 的机会以预防黑人 MSM 感染艾滋病毒的干预措施

基本信息

批准号：
9266363
负责人：
Victoria Frye
金额：
$ 21.08万
依托单位：
CITY COLLEGE OF NEW YORK
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-07-01 至 2019-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9266363
关键词：
AIDS prevention Address Adverse effects Advocate Affect African American Area Awareness Behavior Behavioral Bisexual Caring Centers for Disease Control and Prevention (U.S.)Characteristics Cities Clinical Research Communities Data Development Diffusion of Innovation Education Eligibility Determination Emotional Ensure Exposure to Focus Groups Gays Guidelines HIV HIV Infections HIV diagnosis HIV/STD Health Health Services Homophobia Hour Human immunodeficiency virus test Incidence Individual Infection Infection prevention Insurance Coverage Intervention Interview Link Media Campaign Methods Modeling Motivation New York City Newly Diagnosed Outcome Participant Patients Pharmaceutical Preparations Phase Planning Theory Prevention Prevention strategy Printed Media Prophylactic treatment Provider Psychosocial Factor Qualitative Research Reporting Research Risk Site Social Environment Standardization Surveys Time Training Translating United States aged base black men who have sex with men burden of illness clinical care cost cost effective disorder prevention experience follow-up high risk high risk men improved member men who have sex with men metropolitan multi-component intervention peer pre-exposure prophylaxis prevent public health relevance racial disparity racism response sex risk social social media social stigma standard of care therapy design transmission process treatment duration uptake young men who have sex with men

项目摘要

DESCRIPTION (provided by applicant): Black MSM in the US are affected by HIV at severely disproportionate rates. A key component of HIV prevention for communities at risk is increasing access to and uptake of biomedical HIV prevention, including pre- and post-exposure prophylaxis (PrEP/PEP). PEP is underutilized by those at risk for HIV acquisition after exposure, despite the fact that Centers for Disease Control and Prevention (CDC) issued the first PEP guidelines over 15 years ago. Numerous barriers to successful PEP treatment exist along the "PEP cascade" for Black MSM. Research on the PEP cascade and barriers is sparse, with almost none focused solely on Black MSM. Increasing access to and uptake of PEP among Black MSM has the potential to reduce racial disparities in HIV incidence. To address this gap, we propose to evaluate the acceptability and feasibility of a multi- component intervention designed to increase awareness of, demand for, and access to PEP among Black MSM at high risk of HIV infection. The intervention has three components: 1) a social media campaign to increase demand for PEP among Black MSM; 2) a 24-hour helpline to link patients to timely clinical care; and 3) a PEP advocate intervention, modeled on peer health navigation, to ensure medication access and sustain engagement. The research will involve three phases. In Phase 1, we will conduct formative research to inform the media campaign and the PEP advocate intervention. In Phase 2, we will translate the results of the formative research into optimal messaging across relevant social and print media and standardize the PEP advocate intervention. In Phase 3, to assess impact of the media campaign, we will evaluate social media metrics and calls to the helpline. To assess the acceptability, feasibility and preliminary impact of the PEP advocate intervention, we will survey the first 50 eligible helpline callers and all patients accessing PEP at the clinical study site at 1-week and 3-months post exposure to describe the following outcomes: PEP uptake and completion, PEP care engagement, incident HIV and STIs, HIV testing, PrEP use, sexual risk behavior, select psychosocial factors and receipt of health services.

描述（由适用提供）：美国的黑色MSM受艾滋病毒的影响，率严重不成比例。预防有风险的社区的HIV预防的关键组成部分是增加对生物医学HIV预防的机会，包括预防前和暴露后预防（PREP/PEP）。 PEP在接触后有艾滋病毒遭到艾滋病毒风险的人的利用不足，杜斯皮特（Dospite）这一事实是，疾病控制与预防中心（CDC）在15年前发布了第一个PEP指南。黑色MSM的“ Pep Cascade”沿“ PEP级联”存在许多成功的PEP治疗的障碍。对PEP级联和障碍的研究很少，几乎没有一个仅集中在黑色MSM上。黑色MSM中PEP的获取和吸收的增加有可能减少艾滋病毒事件中的种族分布。为了解决这一差距，我们建议评估旨在提高对HIV感染高风险的黑人MSM的认识，对PEP的认识，对PEP的认识，对PEP的认识，并获得PEP的可接受性和可行性。干预措施有三个组成部分：1）一项社交媒体运动，以增加黑人MSM中对PEP的需求； 2）将患者与及时的临床护理联系起来的24小时热线助攻； 3）旨在确保药物访问并维持参与的旨在建立在同伴健康导航的基础上的鼓舞人心的干预。研究将涉及三个阶段。在第1阶段，我们将进行形成性研究，以告知媒体运动和鼓舞人心的倡导者干预。在第2阶段，我们将将形成性研究的结果转化为相关社会和印刷媒体的最佳消息传递，并标准化PEP倡导者干预。在第3阶段，为了评估媒体运动的影响，我们将评估社交媒体指标和呼吁求助热线。为了评估PEP倡导干预措施的可接受性，可行性和初步影响，我们将调查前50个合格的热线呼叫者，以及所有在临床研究站点访问PEP的患者，在1周内和暴露后3个月来描述以下结果：描述以下结果：PEP摄取和完成，PEP Care Attim和Pep Care Atteript，PEP CAREATION，PED ISTIPT ISTIPT，HIV的性能，性行为，性行为，性行为，性能，进行性，性行为，性行为，性行为，性行为，进行性，性行为，性行为，进行性影响，进行性影响，进行性影响，性能促进，性行为，进行性影响，进行性影响，性能侵害，性能侵害，性行为，性能，进行性影响，进行性影响，进行性危害，进行性侵害，性能，进行性侵害，进行性侵害，性能，进行性侵害。服务。