Prescription Drug Misuse Characteristics in Adolescents and Young Adults: Influence of School Enrollment

青少年和年轻人的处方药滥用特征：入学率的影响

• 批准号: 9286192
• 负责人: TY Stephen SCHEPIS
• 金额: $ 20.68万
• 依托单位: TEXAS STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-06-01 至 2020-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9286192
• 关键词: Accident and Emergency department; Adolescent; Adolescent and Young Adult; Adult; Adult Acute Lymphocytic Leukemia; Affect; Alcohol consumption; Alcohol or Other Drugs use; Alcohols; Attention deficit hyperactivity disorder; Benzodiazepines; Centers for Disease Control and Prevention (U.S.); Characteristics; Classification; Cocaine; Data; Development; Dimensions; Disease; Dropout; Drug abuse; Drug usage; Emergency department visit; Epidemic; Goals; Hallucinogens; Health; High Prevalence; Home environment; Individual; Ingestion; Inhalant dose form; Intervention; Investigation; Knowledge; Label; Longevity; Measures; Medical; Mission; National Institute of Drug Abuse; Opioid; Outcome; Overdose; Pattern; Peer Review; Performance; Pharmaceutical Preparations; Population; Population Heterogeneity; Prevalence; Prevention; Prevention program; Preventive treatment; Problem behavior; Process; Psychopathology; Public Health; Publications; Research; Risk; Risk Behaviors; Role; Sampling; Sarin; School Enrollments; Schools; Secondary Schools; Series; Source; Student Dropouts; Students; Subgroup; Substance Use Disorder; Surveys; Symptoms; Techniques; Time; Tobacco use; Tranquilizing Agents; United States Substance Abuse and Mental Health Services Administration; Vulnerable Populations; age group; aged; base; behavioral health; college; comparative; drug of abuse; health data; high school; innovation; knowledge base; marijuana use; misuse of prescription only drugs; nonmedical use; opioid misuse; opioid use disorder; overdose death; prescription opioid; prevent; psychosocial; sedative; statistics; theories; trait; treatment program; university student; vulnerable adolescent; young adult

PROJECT SUMMARY/ABSTRACT Emerging data indicate that the prevalence of prescription drug misuse (PDM) in adolescents and young adults is heavily influenced by school status, with higher rates of opioid and tranquilizer/sedative (i.e., largely benzodiazepine) misuse in those not in school and higher rates of stimulant use among students. Other research indicates that younger individuals not in school have more concerning substance use profiles and related consequences, with adolescent school dropouts particuarly vulnerable. That said, no research has evaluated PDM characteristics, like motives or diversion sources, by school status in adolescent and young adult prescription misusers. The long-term goal of the research team is to understand prescription misusers and PDM processes across the lifespan, aiding intervention developers by identifying treatment targets and vulnerable subgroups of misusers. In this project, using data from multiple years of the National Survey on Drug Use and Health (NSDUH), the overall objectives are to: one, evaluate differences by student status in adolescents and young adults (separately) in PDM correlates, motives, sources, types, SUD symptoms and patterns of concurrent PDM-other drug use (polydrug use); two, establish latent classes of nonmedical users, separately for the following groups: adolescent students, adolescents not in school, young adult students and young adults not in school; and three, compare latent classes on PDM characteristics (e.g., motives), polydrug use and SUD symptoms. Variable selection was guided by Problem Behavior Theory, allowing for examination of risk and protective factors for PDM across a variety of domains. The rationale for the proposed project is that better characterization of adolescent and young adult prescription misusers and PDM processes in those groups will provide clearer targets for interventions focused on PDM. The contribution of this project will be significant because it will identify especially vulnerable adolescents and young adults engaged in PDM, allowing intervention developers to better craft robust prevention and treatment programs to limit and/or treat PDM in the two age groups with the highest prevalence of PDM. Furthermore, the research proposed here is innovative because it represents a significant departure from the current state of the field focused largely on school-based samples by applying accepted techniques and analyses, all previously utilized by the research team, to considerably expand the knowledge base about PDM in a more diverse population of younger individuals. Other sources of innovation include the investigation of a nationally representative and large sample using a comprehensive set of PDM measures, dimensional examination of substance use disorder symptoms (including those from PDM) and use of a well-studied theory to study the influence of a wide variety of risk and protective factors. Rapid dissemination of the knowledge derived from this project has the potential to inform the development of maximally valid intervention options to prevent or reduce PDM and its consequences in adolescents and young adults, all of which is consistent with the mission of NIDA.

项目摘要/摘要 新出现的数据表明，处方药滥用在青少年和年轻人中的流行率 受学校状况的影响很大，阿片类药物和镇静剂/镇静剂的使用率较高(即 非在校学生滥用苯二氮卓类药物)，学生中兴奋剂使用率较高。其他研究 表明不在学校的年轻人有更多关于物质使用概况和相关的 后果，青少年辍学学生尤其容易受到伤害。也就是说，还没有研究评估过 青春期和青壮年学校状况下的人格特征，如动机或转移来源 误用处方药。研究团队的长期目标是了解处方滥用用户和pdm 整个生命周期内的流程，通过识别治疗目标和易损性来帮助干预开发人员 误用用户的子组。在这个项目中，使用了多年来全国毒品使用情况调查和 健康(NSDUH)，总体目标是：第一，根据青少年的学生状况和 青壮年(分别)与并发疾病的动机、来源、类型、SUD症状和模式相关 产品数据管理--其他药物使用(多药使用)；第二，建立潜在的非医疗使用者类别，分别用于 以下群体：青少年学生、失学青少年、青壮年学生和失学青少年 第三，比较潜在班级在产品数据管理特征(例如，动机)、多药使用和SUD方面的差异 症状。变量的选择是由问题行为理论指导的，允许检查风险和 不同领域的产品数据管理的保护因素。提议项目的理由是更好地 青春期和青壮年处方误用者的特征和这些群体中的产品数据管理流程将 为以产品数据管理为重点的干预提供更明确的目标。这个项目的贡献将是巨大的。 因为它将识别从事产品数据管理的特别脆弱的青少年和年轻人，允许 干预开发人员更好地制定强有力的预防和治疗计划，以限制和/或治疗 DM患病率最高的两个年龄段。此外，本文提出的研究具有创新性。 因为它代表着与目前主要专注于以学校为基础的领域的状态的重大背离 通过应用研究小组以前使用的被接受的技术和分析来获取样本 在更多样化的年轻群体中大大扩展关于PDM的知识库。其他 创新的来源包括对具有全国代表性的大样本的调查，使用 全面的产品数据管理措施，药物使用障碍症状的维度检查(包括 那些来自产品数据管理)，并使用一个研究得很好的理论来研究各种风险的影响和保护 各种因素。该项目所产生的知识的迅速传播有可能使 制定最有效的干预方案，以预防或减少PDM及其后果 青少年和青壮年，所有这些都与NIDA的使命一致。