Cognitive Regulation Training and Exercise (CORTEX)-II with Middle-aged Adults

中年认知调节训练与运动（CORTEX）-II

• 批准号: 9335242
• 负责人: Sean P Mullen
• 金额: $ 53.69万
• 依托单位: UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2021-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9335242
• 关键词: Adherence; Adult; Aerobic; Age; Aging; Attitude; Behavior; Behavioral; Brain; Categories; Cognitive; Communities; Dose; Double-Blind Method; Dropout; Early Intervention; Education; Educational Background; Effectiveness; Enrollment; Equation; Evaluation; Exercise; Expectancy; Family; Future; Gender; Health; Healthcare Systems; Home environment; Hour; Informal Social Control; Injury; Intervention; Knowledge; Leisures; Life; Longevity; Maintenance; Measurement; Measures; Memory; Modality; Modeling; Neurocognitive; Outcome; Participant; Patient Self-Report; Perception; Performance; Physical activity; Population; Preparation; Process; Protocols documentation; Public Health; Randomized; Randomized Controlled Trials; Reaction Time; Sampling; Self Efficacy; Short-Term Memory; Social support; Structure; Supervision; Testing; Time; Training; Training Programs; Visuospatial; Work; age group; attentional control; base; cognitive change; cognitive enhancement; cognitive function; cognitive reappraisal; cognitive training; computerized; exercise adherence; exercise intervention; exercise prescription; exercise program; fitbit; fitness; improved; middle age; programs; psychosocial; skills; social

Project Summary Physical activity rates decrease across the lifespan. Relative to other age groups, nationwide estimates of physical activity are among the lowest in midlife. Average weekly usage of fitness facilities in the U.S. is also well below recommended levels of physical activity. Moreover, within the first 6 months of initiating a structured exercise program, dropout rates are approximately 50 percent. “Booster strategies” have mainly been implemented within exercise interventions to increase compliance to study protocols, and it has yet to be determined whether training at the onset of enrollment in an exercise program can reduce attrition and increase long-term adherence and engagement in physical activity with limited professional guidance. Evidence suggests that general cognitive training and training specific to exercise- related cognitive processing has the potential to increase self-efficacy and self-regulatory strategies, and ultimately, exercise behavior maintenance. In the last decade, active videogame (exergaming) interventions have been used with aging populations to make exercise more enjoyable and prepare the brain for action. Active videogames have been successfully delivered within center- and home-based interventions and have yielded positive effects on mobility, cognitive functioning, psychosocial outcomes, and physical activity behavior. The purpose of this double- blinded, randomized controlled study is to compare CORTEX (Cognitive Regulation Training and Exercise), a multi-faceted, general and exercise-specific cognitive training program— involving 20 hours of active and traditional computerized cognitive training, delivered via a training center and at home—to an attention-control condition involving health and wellness informational videos. More specifically, the cognitive training group will emphasize dual-task abilities, memory, visual-spatial processing, as well as self-as-exerciser priming and self- certainty training. We hypothesize that a month-long cognitive training program will enhance cognitive and related self-regulatory functioning and self-efficacy and in turn, increase exercise adherence and engagement within a 12-month aerobic and resistive exercise program at a local fitness facility. We also expect more positive improvements in cognitive and psychosocial functioning among participants in the CORTEX condition as compared to the Video Control condition immediately following the cognitive booster training, and across time.

项目摘要 身体活动率在整个生命周期中会下降。相对于全国其他年龄组 中年人的体力活动估计是最低的。每周平均使用健身器材 美国的健身设施也远低于建议的身体活动水平。此外，在 在启动结构化锻炼计划的前6个月，辍学率约为 百分之五十“助推器策略”主要在运动干预中实施， 增加对研究方案的遵守，还有待确定是否在 开始参加锻炼计划可以减少自然减员， 在有限的专业指导下坚持和参与体育活动。证据 一般认知训练和运动相关认知训练 加工有可能提高自我效能和自我调节策略， 最后是锻炼行为的维持。在过去的十年里，活跃的视频游戏（exergaming） 干预措施已被用于老龄化人口，使锻炼更愉快， 让大脑做好行动准备活动视频游戏已成功交付中心- 和以家庭为基础的干预措施，并产生了积极的影响， 功能、心理社会结果和身体活动行为。这一双重目的-- 盲法随机对照研究是为了比较CORTEX（认知调节训练 和锻炼），一个多方面的，一般和锻炼特定的认知训练计划- 包括20个小时的积极和传统的计算机认知训练，通过一个 培训中心和在家里-注意力控制条件涉及健康和保健 信息视频。更具体地说，认知训练组将强调双任务 能力，记忆，视觉空间处理，以及自我作为锻炼启动和自我， 确定性训练我们假设，一个月的认知训练计划将提高 认知和相关的自我调节功能和自我效能，反过来，增加 在为期12个月的有氧和抗阻运动计划中坚持和参与运动 在当地的健身中心我们还期待在认知和 与对照组相比， 视频控制条件紧随认知助推器训练，并跨越时间。