Reducing the burden of chronic inflammation through dietary integration of Moringa oleifera

描述(申请人提供)：这个IRSDA职业发展奖的中心目标是培养我成为一名独立的全球健康研究员和治疗性植物应用领域的专家的能力。关于使用辣木治疗和预防与慢性炎症相关的疾病的拟议研究将成为我进一步发展事业的平台，包括新的合作、改进的赠款精神和协调不同的国际专家团队的能力。这个奖项将建立在我良好的植物化学/生物技能和丰富的国际经验的基础上，以推进我的职业生涯，并在需要的领域获得新的技能。拟议的研究将在肯尼亚和美国产生重要和相关的健康成果，在肯尼亚建设研究能力，并为未来的全球合作建立合作伙伴。为了实现我的职业发展目标，我组建了一个由罗格斯大学、肯尼亚医学研究所(KEMRI)和肯雅塔大学的导师和联合导师组成的顾问团队。我的团队将帮助我实现：(1)治疗植物生产方面的专业知识；(2)在生物系统中的植物药物评估方面的卓越表现；(3)协调国际跨学科团队，将科学研究和全球卫生发展整合到以影响为导向的项目中。伊利亚·拉斯金将担任我的主要美国导师，她在植物疗法、导师和国际合作方面拥有专业知识。Jennifer Orwa博士将担任我在KEMRI的主要LMIC导师，在那里她领导着传统医学研究中心，她拥有指导我职业发展和研究目标的专业知识。所有合作机构都致力于利用植物和食品中的植物化学物质来改善人类健康，并具备进行这项研究的良好条件。职业目标1和2将增强我的技术技能，而目标3将凌驾于我研发的各个方面。此外，我还有两位合作者将协助我实现该项目的具体目标，另一位负责我的职业发展，他们将通过全球健康专业科学硕士(PSM)学位项目为我提供建议。

DESCRIPTION (provided by applicant): The central goal of this IRSDA career development award is to foster my ability to become an independent global health researcher and expert in the field of therapeutic plant applications. The proposed research on the use of Moringa oleifera to treat and prevent conditions related to chronic inflammation will serve as a platform for furthering my career, including new collaborations, improved grantsmanship and ability to coordinate a diverse team of international experts. This award will build upon my sound phytochemical/ biological skills and substantial international experience to advance my career and acquire new skills in needed areas. The proposed research will have important and relevant health outcomes in Kenya and the US, build research capacity in Kenya, and establish partners for future global collaborations. In order to fulfill my career development goals I have assembled an advisory team of mentors and co-mentors from Rutgers University, the Kenya Medical Research Institute (KEMRI), and Kenyatta University. My team will help me achieve: (1) expertise in therapeutic plant production; (2) excellence in the evaluation of botanicals in biological systems; and (3) coordination of international interdisciplinary teams for integration o scientific research and global health development in impact-driven projects. Ilya Raskin will serve as my primary US-mentor, who has expertise in plant-based therapeutics, mentorship, and international collaboration. Dr. Jennifer Orwa will serve as my primary LMIC-mentor at KEMRI, where she leads the Center for Traditional Medicine Research, and has the expertise to guide my career development and research goals. All collaborating institutes are dedicated to utilizing phytochemicals in plants and foods to improve human health and are well-equipped to perform the research. Career goals 1 and 2 will bolster my technical skills, while goal 3 will overarch all aspects of my research and development. In addition I have two collaborators who will assist me in specific aims of the project, and one for my career development who will advise me through the Professional Science Masters (PSM) in Global Health degree program.