Mount Sinai Injury Control Research Center (MS-ICRC)

西奈山伤害控制研究中心（MS-ICRC）

• 批准号: 9425411
• 负责人: Wayne A. Gordon
• 金额: $ 77.62万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-01 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9425411
• 关键词: Mount; Sinai; Injury; Control; Research

ABSTRACT The Mount Sinai Injury Control and Research Center (MS-ICRC) will continue, in the proposed funding period, to focus on ameliorating the secondary and tertiary conditions that occur after traumatic brain injury (TBI), to address two goals: (1) improving quality of life after TBI and (2) extending the life span of people injured after age 40. We have added an additional emphasis: reducing violence and criminal behavior in youth who are at high risk. The proposed Research Program of the MS-ICRC includes: (1) An investigation of the impact of a behavioral intervention on violence and recidivism amongst youth (with TBI and without) who are on parole. This study “translates” an intervention we developed for an adult TBI population for use with adolescents at-risk for violence, and it comprises the first study of an intervention for young offenders with TBI. (2) A pilot prospective cohort study of individuals who sustained a TBI after age 40, to document health issues and other factors that may contribute to the accelerated aging and pre-mature death that has been documented in TBI survivors. (3) An analysis of a database developed by the Texas juvenile justice system to explore the relationship between TBI (and other health factors) and youth criminality, with a particular focus on violent offenses. This policy research follows extensive outreach by the MS-ICRC to the juvenile justice system in Texas that resulted in their decision to screen their population for TBI (using the MS-ICRC’s Brain Injury Screening Questionnaire [BISQ]). (4) The establishment of a longitudinal database of all college athletes at St. John’s University in New York City, to document at time of college admission lifetime history of concussion and to then prospectively document concussions sustained during college both on and off the field. Student-athletes will be followed to define the long-term consequences of concussions. This project will be fully manualized for replication in other institutions, to move toward the establishment of a national registry of college sports concussions. (5) A program of exploratory projects, to encourage other researchers to expand their work to address the MS- ICRC’s long-term goals. Together, Projects 1 and 3 have strong policy implications for developing system-wide interventions to identify children with TBI at the earliest point possible and for providing subsequent accommodations, i.e., systemic interventions to reduce violence and criminality in young offenders, or school- based interventions to prevent children with TBI from taking the path that often leads from untreated long-term challenges consequent to injury to criminal behavior, homelessness and other forms of social failure. The proposed Outreach Program addresses MS-ICRC goals by building on the output of our current activities (2007-2012) and by weaving the results of proposed activities into outreach, as new “products” are developed and new implications for action emerge. Specifically, three interventions (cognitive behavioral therapy adapted to treat depression post TBI, and the Executive Plus and STEP treatment programs for post-TBI executive dysfunction) have been developed, evaluated and manualized. Planned outreach will focus on broad dissemination and support for adoption of these valuable additions to the TBI treatment arsenal. A second current focus is on screening for “hidden” TBI, through further validation of the BISQ and its adaptation for web-based administration. Outreach in the next five years will stress wider dissemination of the BISQ to screen additional populations, with the goal of effecting changes in policy in schools and in other settings where screening is needed to identify individuals with brain-injury related challenges, so that accommodations can be provided to prevent failure associated with unrecognized injury. Another emphasis is being placed on working with marketing experts to better tailor MS-ICRC outreach to meet the needs of our several constituencies. A new element of MS-ICRC outreach will be a Policy Think Tank, to review evidence based on MS-ICRC research and from the established knowledge base, and then to detail means and strategies to achieve policy change; the first area will be establishing systematic screening for “hidden” TBI. The Training and Education Program will continue to focus on supplying the field with qualified professional injury prevention practitioners and researchers, in the spirit of the training program established in 2007. Formal training will include a 2-year post-doctoral fellowship program and a 1-year pre-doctoral externship. In addition, we will educate service providers through webinars and workshops, symposia and lectures at professional conferences and institutions; we also provide numerous resources for professionals downloadable (gratis) on our website. Recommendations for curricula changes to be incorporated into programs for medical and other professional training will also be developed.

抽象的 西奈山伤害控制和研究中心（MS-ICRC）将在拟议的资助期内继续： 专注于改善创伤性脑损伤（TBI）后发生的继发性和继发性病症， 实现两个目标：(1) 改善 TBI 后的生活质量；(2) 延长 TBI 后受伤人员的寿命 40 岁。我们增加了一个额外的重点：减少青少年的暴力和犯罪行为 高风险。 MS-ICRC 拟议的研究项目包括： (1) 调查行为的影响 对假释青少年（无论是否患有 TBI）的暴力和累犯进行干预。这项研究 “翻译”我们为成人 TBI 人群开发的干预措施，用于有患 TBI 风险的青少年 它是第一个针对患有 TBI 的年轻罪犯进行干预的研究。 （二）试点前景 对 40 岁后遭受 TBI 的个体进行队列研究，以记录健康问题和其他因素 可能会导致 TBI 幸存者加速衰老和过早死亡。 (3) 对德克萨斯州少年司法系统开发的数据库进行分析，以探讨两者之间的关系 TBI（和其他健康因素）和青少年犯罪，特别关注暴力犯罪。这项政策 红十字国际委员会在德克萨斯州的青少年司法系统中开展了广泛的外展活动，并开展了这项研究，结果 他们决定对民众进行 TBI 筛查（使用 MS-ICRC 的脑损伤筛查问卷 [BISQ]）。 (4) 建立纽约州圣约翰大学所有大学生运动员的纵向数据库 约克市，在大学入学时记录一生的脑震荡史，然后前瞻性地记录 记录大学期间场内场外的脑震荡。学生运动员将被跟踪 定义脑震荡的长期后果。该项目将完全手动化，以便在其他项目中复制 机构，努力建立国家大学体育脑震荡登记处。 (5) 一个 探索性项目计划，鼓励其他研究人员扩大他们的工作以解决 MS- 红十字国际委员会的长期目标。项目 1 和项目 3 对全系统的发展具有强烈的政策影响 尽早识别 TBI 儿童并提供后续干预措施 便利措施，即减少青少年罪犯或学校暴力和犯罪行为的系统性干预措施 预防 TBI 儿童走上长期未经治疗的道路的干预措施 犯罪行为伤害、无家可归和其他形式的社会失败带来的挑战。 拟议的外展项目以我们当前活动的成果为基础，以实现 MS-ICRC 的目标 (2007-2012) 并随着新“产品”的开发，将拟议活动的结果融入到外展活动中 并且出现了新的行动含义。具体来说，三种干预措施（适应的认知行为疗法 治疗 TBI 后抑郁症，以及针对 TBI 后高管的 Executive Plus 和 STEP 治疗计划 功能障碍）已被开发、评估和手动化。计划外展活动将重点关注广泛的 传播和支持采用这些宝贵的 TBI 治疗手段。一秒钟 当前的重点是通过进一步验证 BISQ 及其改编来筛查“隐藏”TBI 基于网络的管理。未来五年的外展活动将强调 BISQ 更广泛地传播到筛查 增加人口，目标是改变学校和其他环境中的政策 需要进行筛查来识别患有脑损伤相关挑战的个人，以便能够提供住宿 旨在防止与未识别的伤害相关的故障。另一个重点是工作 与营销专家合作，更好地定制 MS-ICRC 的外展活动，以满足我们多个支持者的需求。一个 MS-ICRC外展工作的新内容将是政策智囊团，以审查基于MS-ICRC的证据 研究并从已建立的知识库出发，然后制定实现政策的详细手段和策略 改变;第一个领域是建立“隐藏”TBI 的系统筛查。 培训和教育计划将继续侧重于为该领域提供合格的专业人员 本着 2007 年制定的培训计划的精神，培训伤害预防从业人员和研究人员。 正式 培训将包括为期 2 年的博士后奖学金计划和 1 年的博士前实习。此外， 我们将通过网络研讨会和讲习班、研讨会和专业讲座来教育服务提供商 会议和机构；我们还为专业人士提供大量资源，可在以下位置（免费）下载： 我们的网站。将课程变更纳入医学和其他项目的建议 还将开展专业培训。