Development and pilot testing of a multimodal web-based program to address heavy drinking during smoking cessation

开发和试点测试多模式网络计划，以解决戒烟期间酗酒问题

• 批准号: 9226007
• 负责人: Christopher W. Kahler
• 金额: $ 35.27万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-03-01 至 2019-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9226007
• 关键词: Abstinence; Address; Alcohol consumption; Alcoholic beverage heavy drinker; Alcohols; Clinical; Collaborations; Communities; Comorbidity; Computers; Counseling; Development; Effectiveness; Elements; Enrollment; Failure; Feedback; Foundations; Head Cancer; Health; Health Planning; Heavy Drinking; Individual; Internet; Intervention; Link; Malignant neoplasm of pancreas; Modality; Motivation; National Institute on Alcohol Abuse and Alcoholism; Neck Cancer; New York; Online Systems; Outcome; Outcome Assessment; Participant; Persons; Pilot Projects; Population; Preparation; Program Development; Public Health; Randomized; Randomized Clinical Trials; Randomized Controlled Trials; Recommendation; Recruitment Activity; Research; Research Personnel; Resources; Risk; Sampling; Site; Smoke; Smoker; Smoking; Specific qualifier value; Telephone; Testing; Text; Treatment Efficacy; Woman; Work; alcohol effect; alcohol intervention; arm; brief alcohol intervention; cigarette smoking; cost; design; drinking; evidence base; follow-up; high risk; improved; men; multimodality; non-smoker; pilot trial; population health; programs; public health relevance; quitline; randomized trial; relative cost; response; satisfaction; smoking cessation; smoking intervention; smoking prevalence; smoking relapse; success; web page; web site

 DESCRIPTION (provided by applicant): Comorbid cigarette smoking and heavy drinking (HD) - for women consuming 8+ drinks a week or 4+ drinks on a single occasion and for men consuming 15+ drinks a week or 5+ on a single occasion - is a major public health concern. Smokers engage in HD at high rates, and HD is robustly associated with low rates of smoking cessation. Furthermore, smoking and HD combine to dramatically increase the risk of head, neck, and pancreatic cancers in addition to having strong detrimental effects on overall health. To address this public health challenge, we have developed and tested a counseling approach that incorporates brief alcohol intervention into smoking cessation counseling. In both face-to-face and telephone formats, this combined counseling approach has demonstrated substantial promise for improving both drinking and smoking outcomes compared to matched control conditions? Adapting this approach for use in a web-based smoking cessation program for HD smokers is a compelling next step for increasing its population reach. Millions of smokers search online for smoking cessation information each year, and hundreds of thousands register on publicly available web-based cessation programs, yet none of these sites address heavy drinking in a comprehensive and integrated manner. A website specifically designed for HD smokers would provide an exceptional opportunity to enhance smoking cessation rates and concurrently intervene on HD. The overall objective of this project is to develop and pilot test a web-based smoking cessation program that specifically addresses HD. The project builds upon a well-established, evidence-based smoking cessation website, BecomeAnEX.org, which enrolls approximately 2,300 new users each month. The project will occur in two stages. In Stage 1a, we will to create EX-HD, an expanded mirror version of BecomeAnEx.org that incorporates key elements of our previously tested approaches for addressing HD in smoking cessation and NIAAA's evidence-based website for HD, Rethinking Drinking. We will pilot this beta version of EX-HD with 30 HD smokers recruited from BecomeAnEX, examining feasibility and acceptability using participant feedback and site use metrics. EX-HD will be revised in response to this feedback in preparation for Stage 1b work. Stage 1b will involve a pilot randomized clinical trial in which 120 HD smokers recruited through BecomeAnEX will be randomly assigned to either the standard BecomeAnEX program or to EX-HD and followed for 6 months in order to obtain initial estimates of the potential of EX-HD to reduce HD and increase smoking cessation. Results will provide the foundation for a fully-powered Stage II randomized trial. Ultimately, this research could result in a well- specified, efficacious intervention that wuld have great population reach with limited cost relative to in-person counseling and could have an especially powerful impact on public health by concurrently increasing smoking cessation and reducing HD.

 描述（由适用提供）：合并的吸烟和大量饮酒（HD） - 对于每周喝8杯以上饮料或一次饮料的女性，对于每周喝15杯以上的男性，一次或一次喝了5次饮料 - 是一个主要的公共健康问题。吸烟者以高率参与高清，高清与戒烟率低相关。此外，除了对整体健康有强大的不利影响外，吸烟和高清大大增加了头部，颈部和胰腺癌的风险。为了应对这一公共卫生挑战，我们已经开发并测试了一种咨询方法，该方法将简短的酒精干预纳入了戒烟咨询中。在面对面和电话格式中，这种合并的咨询方法与匹配的对照条件相比表现出了重大的前景，可以改善饮酒和吸烟结果？适应用于高清吸烟者的基于网络的吸烟计划中使用这种方法是增加其人口覆盖范围的下一步。数百万吸烟者每年在线搜索戒烟信息，成千上万的吸烟者在基于网络的公开戒烟计划上注册，但是这些网站都没有以全面而综合的方式解决大量饮酒。专门为高清吸烟者设计的网站将为提高戒烟率并同时干预HD提供特别的机会。该项目的总体目的是开发和试点测试一个基于网络的吸烟计划，该计划专门针对高清。该项目建立在一个公认的，循证的戒烟网站bea eanex.org的基础上，该网站每月约有2300名新用户。该项目将分为两个阶段。在第1A阶段，我们将创建Ex-HD，这是一个扩展的ableAnex.org的镜像版本，它结合了我们先前测试的方法的关键要素，用于解决戒烟中的HD和NIAAA基于循证的HD网站，用于重新思考饮酒。我们将通过参与参与反馈和现场使用指标来检查该Beta版的EX-HD版本的EX-HD，并检查了30个HD吸烟者，从而检查了可行性和可接受性。将对此反馈进行修订，以准备为1B阶段的工作做准备。第1B阶段将涉及一项飞行员随机临床试验，在该试验中，通过beateAnex募集的120个HD吸烟者将被随机分配到标准的beateAnex计划或EX-HD计划，然后进行6个月，以便获得减少HD的潜力的初步估计，以减少HD和增加吸烟。结果将为完全动力的II期随机试验提供基础。最终，这项研究可能会导致一项良好的，有效的干预措施，相对于面对面的咨询，成本有限的人口范围很高，并且通过同时增加戒烟和减少HD，可能会对公共卫生产生特别强大的影响。