A Prototype Stationary X-Ray Source Digital Breast Tomosynthesis System

原型固定式 X 射线源数字乳腺断层合成系统

• 批准号: 9287706
• 负责人: PAUL R SCHWOEBEL
• 金额: $ 34.97万
• 依托单位: SRI INTERNATIONAL
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-03-15 至 2021-02-27
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9287706
• 关键词: Algorithms; Anodes; Back; Breast; California; Capital; Cathodes; Characteristics; Clinical; Clinical Trials; Custom; Data; Development; Diagnostic radiologic examination; Digital Breast Tomosynthesis; Digital Mammography; Dimensions; Early Diagnosis; Elements; Filament; Geometry; Goals; Image; Image Enhancement; Individual; Industrialization; International; Maintenance; Measures; Mechanics; Medical Imaging; Medical center; Motion; Motor; Movement; Patients; Performance; Peripheral; Research; Resolution; Roentgen Rays; Scanning; Slice; Source; Speed; Spottings; Study Section; System; Technology; Testing; Time; Tube; Tungsten; United States National Institutes of Health; Universities; Woman; base; breast cancer diagnosis; cost; design; design and construction; detector; imaging system; improved; novel; novel strategies; operation; programs; prototype; reconstruction; tomosynthesis; vibration; voltage

PROJECT SUMMARY/ABSTRACT Digital breast tomosynthesis (DBT) has been shown to significantly increase accuracy in the early detection and diagnosis of breast cancer. The goals of this proposal are to further enhance the efficacy and performance of this type of imaging by removing mechanical motion of the X-ray tube through the development of a stationary X-ray source DBT system. The development of a stationary X-ray source DBT system will enable a 3- to over 10-fold decrease in scan time relative to that of existing commercial systems. Shorter scan times improve image quality by reducing instances of patient motion without introducing image blurring due to tube movement or vibration – keys to exploiting the improved imaging sensitivity of DBT. In addition, it is anticipated that the proposed system could expand the availability of DBT by decreasing up-front capital, operating, and maintenance costs. We expect that lower-cost, higher-performance imaging will accelerate the on-going displacement of full-field digital mammography by DBT, thereby providing more women with higher quality imaging sooner.

项目概要/摘要 数字乳腺断层合成 (DBT) 已被证明可以显着提高早期检测的准确性 和乳腺癌的诊断。该提案的目标是进一步提高效率和性能 通过开发一种消除 X 射线管的机械运动来实现这种类型的成像 固定式 X 射线源 DBT 系统。固定 X 射线源 DBT 系统的开发将使 与现有商业系统相比，扫描时间减少 3 至 10 倍以上。更短的扫描时间 通过减少患者运动次数来提高图像质量，而不会因管道而导致图像模糊 运动或振动——利用 DBT 改进的成像灵敏度的关键。此外，预计 拟议的系统可以通过减少前期资本、运营和成本来扩大 DBT 的可用性 维护成本。我们预计成本更低、性能更高的成像将加速正在进行的 DBT 取代全视野数字乳腺 X 线摄影，从而为更多女性提供更高质量的图像 尽早成像。