Surgical Oncology Research Training Grant

描述（由申请人提供）：我们建议继续我们的项目，为有兴趣从事学术肿瘤外科手术的年轻外科医生提供肿瘤研究培训。实习生将是外科住院医师，至少有2年的研究生临床经验。在过去的25年里，我们的外科肿瘤研究培训计划已经支持了大约50名年轻的实习外科医生的研究事业。我们现正申请26至30年的资助。为期两年的培训计划的目标是为个人提供以下方面的深入研究经验：(1)假设制定，(2)实验设计，(3)数据分析，(4)口头和书面陈述。该计划的最终目标是教授科学方法和实验室技术，以便学员在完成外科培训后能够进行高质量的肿瘤学独立研究。这种研究经验将使学员能够申请学术机构的初级教员职位，并成为独立的临床研究者和转化研究人员。课程将根据学员及其导师的兴趣而有所不同。该课程旨在提供基础科学和转化科学，以及医学肿瘤学，放射肿瘤学和临床外科肿瘤学。过去的学员在广泛的学科领域工作，包括肿瘤免疫学、癌细胞生物学、分子遗传学、分子病理学、靶向治疗、生长和分化。学员、导师和项目主管之间实现了密切的联系。学员需要参加纪念斯隆-凯特琳癌症中心（MSKCC）的每周会议和教学讲座，包括研究基础，研究报告以及临床肿瘤学主题。研修生的科研质量突出，10年来大部分研修生都留在了学术界。该项目仍然是外科部门的主要承诺，并受益于我们机构最近增加的研究人员和研究设施。

DESCRIPTION (provided by applicant): We propose to continue our program to provide research training in oncology to young surgeons interested in a career in academic surgical oncology. Trainees will be surgical residents with at least 2 years of postgraduate clinical experience. Our Surgical Oncology Research Training Program has supported the research careers of approximately 50 young trainee surgeons over the past 25 years. We are now applying for funding of years 26-30. The goals of the two-year training program are to provide individuals with an intensive research experience in (1) hypothesis formulation, (2) experimental design, (3) data analysis, and (4) oral and written presentation. The ultimate objective of the program is to teach the scientific method and laboratory techniques so that the trainees can perform high quality independent research in oncology upon completion of their surgical training. This research experience will enable trainees to apply for positions as junior faculty members in academic institutions and become independent and mentored clinical investigators and translational researchers. The program will vary according to the interest of the trainees and their preceptors. The program curriculum is designed to provide exposure to basic and translational science, as well as medical oncology, radiation oncology and clinical surgical oncology. Past trainees have worked in a wide variety of disciplines, including tumor immunology, cancer cell biology, molecular genetics, molecular pathology, targeted therapeutics, and growth and differentiation. Close contact between the trainees, preceptors and program director has been achieved. Trainees are required to attend weekly conferences and didactic lectures at Memorial Sloan-Kettering Cancer Center (MSKCC) that include the fundamentals of research, research presentations as well as topics in clinical oncology. The scientific quality of research performed by the trainees has been outstanding, and most of the fellows in the past 10 years have remained in academia. The program continues to be a major commitment of the Department of Surgery and has benefited from the recent increase in research faculty and research facilities at our institution.