SURGICAL ONCOLOGY RESEARCH TRAINING GRANT (T32)

描述(申请者描述)：这个外科肿瘤学培训计划旨在吸引和培训具有外科临床背景的医生参加为期两年的基础肿瘤学研究奖学金。这一计划的主要重点将是研究技能的发展，这些技能对临床外科肿瘤学具有翻译适用性。这将通过实习生与北卡罗来纳大学莱恩伯格综合癌症中心一名在内科科学家培训方面有经验的知名癌症研究调查员进行紧张的个人参与来实现。每个学员都有一位外科肿瘤学的临床导师，以帮助协调学员的翻译研究重点。该计划的第一年强调研究方法、课程和基本科学技术，以确保研究员获得癌症研究各个领域的知识和方法。正式的课程将由学员在生物统计学、免疫学、分子生物学、信号转导或流行病学等领域的个性化课程中完成。随着个人研究项目的成熟，他们将向基础科学审查委员会提交他们的工作，以确保他们能够为自己对实验的解释进行辩护。受训人员的选择将是竞争性的，优先考虑已完成临床培训并通过临床经验提高了对肿瘤学问题领域的识别能力的研究员。如果候选人表现出作为学术外科医生的非凡潜力，那么他们将被考虑完成两到三年的住院医生工作。共有两名学员参加该项目，每年挑选一名研究员，为期两年。

DESCRIPTION (Applicant's Description): This Surgical Oncology Training program is designed to attract and train physicians with a clinical background in surgery in a two- year fellowship of basic oncological research. The major emphasis of this program will be on the development of research skills which have a translational applicability to clinical surgical oncology. This will be accomplished through an intense, personal involvement of the trainee with an established cancer research investigator at the UNC Lineberger Comprehensive Cancer Center who has experience in the training of physician scientists. Each trainee has a clinical mentor in surgical oncology to help to coordinate the trainee's translational research focus. The first year of the program emphasizes research methodology, coursework, and basic science techniques to ensure that the fellows receive the knowledge and methodology in various fields of cancer research. Formal coursework will be completed by the trainee in individualized programs in areas such as biostatistics, immunology, molecular biology, signal transduction, or epidemiology. As the individual's own research project matures, they will present their work to a basic science review committee to ensure they are able to defend their interpretation of their experiments. Selection of the trainees will be competitive and preference will be for fellows who have completed their clinical training and whose identification of problem areas in oncology has been enhanced by the clinical experience. Candidates will be considered who have completed two to three years of residency if they demonstrate exceptional promise as academic surgeons. A total of two trainees will participate in the program, one fellow being selected annually for a two year period.