Training Program in Developmental Hematology

 描述(由申请者提供)：这是华盛顿大学医学院儿科发育血液学培训项目的竞争性更新。该计划将为儿科医生(医学博士或医学博士)提供博士后研究经验，长期目标是培养能够为生物医学研究做出重要贡献的独立研究人员。该计划将每年资助一名二年级学生(PGY-4)和一名三年级学生(PGY-5)。受训人员将从华盛顿大学医学院儿科的血液学-肿瘤学奖学金计划中招募。该奖学金计划包括三到四年的培训，其中只有两年将得到T32的支持。血液学-肿瘤学奖学金包括许多具有血液学研究背景的合格申请者。受训者将参加一个正式的研讨会系列，其中包括对发育血液学当前研究的讨论，以及统计学、研究设计和研究伦理行为的教学会议。学员可以在华盛顿大学的多个实验室进行博士后研究，前提是这些研究与发育血液学领域相关。该计划为学员提供两条途径。在路径A中，重点是基础科学遗传学/基因组学经验、核心课程和基础科学课程。在路径B中，重点放在临床/翻译基因组科学上，包括“以患者为中心的实验室”经验、核心课程和临床调查、转化医学或遗传学/基因组学课程。艾伦·施瓦茨，医学博士，博士，将担任项目主任。这项计划的持续支持将有助于缩小基础发育生物学家和儿科临床医生之间的差距。

 DESCRIPTION (provided by applicant): This is a competitive renewal of a training program in Developmental Hematology in the Department of Pediatrics at Washington University School of Medicine. The program will provide pediatric physicians (MD's or MD, PhD's) with postdoctoral research experience with the long-term goal of producing independent investigators capable of making important contributions to biomedical research. The program will support one second-year (PGY-4) and one third-year fellow (PGY-5) each year. The trainees will be recruited from the Hematology-Oncology fellowship program in the Department of Pediatrics at Washington University School of Medicine. The fellowship program is comprised of three to four years of training, only two of which will be supported by the T32. The Hematology-Oncology fellowship includes many qualified applicants with backgrounds in hematology research. Trainees will participate in a formal seminar series that includes a discussion of current research in developmental hematology, along with didactic sessions in statistics, design of research, and the ethical conduct of research. Trainees may perform their postdoctoral research in a wide range of laboratories at Washington University, provided the research is relevant to the field of developmental hematology. The Program offers trainees two Pathways. In Pathway A, the emphasis is on basic science genetics/genomics experiences, a core curriculum, and a basic-science curriculum. In Pathway B, the emphasis is on clinical/translational genomic science with "patient-oriented laboratory"-based experiences, a core curriculum and a clinical investigation, translational medicine or genetics/genomics curriculum. Alan L. Schwartz, MD, PhD, will serve as Program Director. The continued support of this program will help to close the gap between basic developmental biologists and pediatrician clinicians.