Psychoneurological Symptoms in Situationally Stressed Low Income Mothers

处于情境压力的低收入母亲的心理神经症状

基本信息

  • 批准号:
    9548909
  • 负责人:
  • 金额:
    $ 3.39万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2017
  • 资助国家:
    美国
  • 起止时间:
    2017-08-01 至 2019-07-31
  • 项目状态:
    已结题

项目摘要

Project Summary/Abstract In the United States, more than 10% of mothers, or 8.5 million, live in poverty, placing the mothers in conditions of chronic situational stress. Low income mothers are exposed to chronic situational stress, due in part to the economic hardship and additional stressors associated with the responsibilities of motherhood. Exposure to economic hardship is associated with higher reports of pain, fatigue, sleep disturbance, depressed mood, and cognitive dysfunction, known as the psychoneurological symptoms. These symptoms can significantly impair a mother by interfering with her ability to function and mother. Compromises to a mother's functioning places her children at higher lifetime risks of impaired cognitive and emotional development; infants and toddlers are the most vulnerable to these consequences. To date, attempts to intervene on situational stress-related symptoms in low income mothers have focused on depressive symptoms. These interventions have met with varied levels of efficacy. The limited efficacy may be because interventions addressing depressive symptoms do not include pain, which is experienced by 50% of low income mothers. An alternative and novel approach is to reconceptualize the stress-related symptoms as psychoneurological symptoms in order to consider underlying biological mechanisms that could be targeted by interventions. The proposed study will describe psychoneurological symptoms in a sample of low income mothers under chronic situational stress and determine the associations of the symptoms with situational stress and with maternal and child outcomes. This study will be a secondary analysis of data from 356 low income mothers and will combine the data from two parent studies conducted at the University of North Carolina at Chapel Hill. The proposed study will analyze key variables of situational stress, psychoneurological symptoms, maternal functioning, and child behavior and development. The project has three aims: to describe the intensity of the psychoneurological symptoms by comparing a simple, data-naïve approach (composite score) against a complex, innovative data-driven approach (reduced rank regression); to use multiple regression analyses to explore how variations in levels of chronic situational stress are associated with intensity of psychoneurological symptoms; and to use multiple regression analyses to determine the relationship of psychoneurological symptoms to mother's functional status (physical functioning, social functioning, role functioning, mothering) and child behavioral and developmental status. This study addresses NINR's Innovative Questions in Symptom Science concerning the impact of adverse symptoms across diverse populations by researching the behavioral dynamics of symptoms (1-1) and how lifestyle factors and environmental conditions impact symptoms (1-3). The findings from this study will be the first step towards determining personalized biomarkers of psychoneurological symptoms and, eventually, developing targeted symptom management interventions to improve quality of life for the mothers.
项目摘要/摘要 在美国,超过10%的母亲,即850万人生活在贫困中,使母亲们 慢性情景应激状态。低收入母亲面临长期的情境压力,原因是 部分原因是经济困难和与为人母亲的责任相关的额外压力。 暴露在经济困难中与疼痛、疲劳、睡眠障碍、抑郁的报告有关 情绪和认知功能障碍,称为精神神经学症状。这些症状可能 通过干扰母亲的功能和母亲的能力而严重损害母亲的能力。对母亲的妥协 功能正常使她的孩子一生中认知和情绪发育受损的风险更高;婴儿 而蹒跚学步的孩子最容易受到这些后果的影响。到目前为止,试图对情景进行干预 低收入母亲的压力相关症状主要集中在抑郁症状上。这些干预措施 都遇到了不同程度的疗效。疗效有限可能是因为干预措施解决了 抑郁症状不包括疼痛,50%的低收入母亲会经历疼痛。另一种选择 新的方法是将与应激相关的症状重新定义为精神神经学症状 以考虑干预措施可能针对的潜在生物学机制。 这项拟议的研究将描述以下低收入母亲的精神神经学症状。 慢性情景应激,并确定症状与情景压力和 孕产妇和儿童的结果。这项研究将对356名低收入母亲的数据进行二次分析 并将结合北卡罗来纳大学教堂山分校进行的两项家长研究的数据。 这项拟议的研究将分析环境压力、心理神经症状、母亲 功能,以及儿童行为和发展。该项目有三个目标:描述 通过比较简单、数据幼稚的方法(综合分数)和 复杂、创新的数据驱动方法(降阶回归);使用多元回归分析 探索慢性情景应激水平的变化与精神神经学强度之间的关系 并使用多元回归分析来确定精神神经学的关系 母亲功能状态的症状(身体功能、社会功能、角色功能、育儿) 以及儿童的行为和发育状况。 这项研究解决了NINR在症状科学中关于不良影响的创新问题 通过研究症状的行为动力学(1-1)以及如何 生活方式因素和环境条件影响症状(1-3)。这项研究的发现将是 第一步是确定心理神经症状的个性化生物标记物,最终, 制定有针对性的症状管理干预措施,以提高母亲的生活质量。

项目成果

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Rebecca Salomon其他文献

Rebecca Salomon的其他文献

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{{ truncateString('Rebecca Salomon', 18)}}的其他基金

Psychoneurological Symptoms in Situationally Stressed Low Income Mothers
处于情境压力的低收入母亲的心理神经症状
  • 批准号:
    9393384
  • 财政年份:
    2017
  • 资助金额:
    $ 3.39万
  • 项目类别:

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