APPLIED RESEARCH FOR IMPROVING THE BEHAVIORAL MANAGEMENT

改善行为管理的应用研究

• 批准号: 3421503
• 负责人: MOLLIE ANNE BLOOMSMITH
• 金额: $ 15.31万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-09-30 至 1993-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3421503
• 关键词: Betaherpesvirinae; Macaca mulatta; animal breeding; animal care; animal colony; animal welfare research; ethology; germ free condition; reproduction; stress; veterinary science

The proposed behavioral research program is designed to improve the management of captive rhesus monkeys and to maximize the breeding potential of the resulting SPF rhesus colony. Improvements in the environmental conditions for singly and socially housed rhesus will be studied, documenting effects on activity, behavioral pathologies and agonism. Four categories of environmental enrichment will be evaluated and compared. The adequacy of the proposed SPF derivation strategy for producing animals that are competent breeders and parents will be evaluated. Relationships between environmental enrichment, hormonal measures of stress, behavioral indices of stress, genetic characterization of animals and Herpes B virus status will be statistically analyzed. This will have practical application in identifying animals that are less susceptible to the detrimental consequences of single caging and in beginning a selective breeding program of such animals. Within our SPF derivation strategy, defining a behavioral profile predictive of HBV infection expression will allow social groupings to be made that minimize the probability of new exposures to infection. Results from all of these research projects will have direct application to improving the care and management of rhesus monkey colonies.

拟议的行为研究计划旨在改善 圈养恒河猴的管理， 由此产生的SPF恒河猴群体的繁殖潜力。 改善环境条件， 将对社会圈养的恒河猴进行研究， 活动、行为病理和激动。 四类 将对环境富集进行评价和比较。 的 建议的SPF衍生策略是否足以产生 动物是称职的育种者和父母将 评估。 环境富集， 压力的激素测量，压力的行为指数，遗传 动物的表征和疱疹B病毒状态将 统计分析。 这将有实际应用， 识别出不易受有害物质影响的动物 单笼的后果，并在开始选择性 这类动物的繁殖计划。 在我们的SPF推导中 策略，定义预测HBV感染的行为特征 表达将允许社会群体， 新感染的可能性。 结果来自所有 这些研究项目将直接应用于改善 恒河猴群的护理和管理。