Cancer Imaging

癌症影像

• 批准号: 9491726
• 负责人: Timothy Charles Doyle
• 金额: $ 12.37万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9491726
• 关键词: Animal Cancer Model; Animal Housing; Animal Model; Animals; Chemistry; Consultations; Custom; Cyclotrons; Data Analyses; Doctor of Philosophy; Early Diagnosis; Ensure; Equipment; Experimental Designs; Fees; Fostering; Future; Goals; Image; Imaging technology; Industry; Institutes; Laboratories; Laboratory Research; Location; Magnetic Resonance Imaging; Malignant Neoplasms; Measures; Molecular; Molecular Probes; Operative Surgical Procedures; Optics; Positron-Emission Tomography; Radiology Specialty; Recovery; Reporter Genes; Research; Research Personnel; Resource Sharing; Resources; Scientist; Services; Technology; Time; Tissues; Training; Ultrasonography; Update; Work; anticancer research; bioluminescence imaging; cancer imaging; cancer stem cell; clinical application; cost; design; experience; fluorescence imaging; imaging detection; imaging facilities; imaging modality; imaging probe; imaging system; in vivo; instrument; instrumentation; member; microCT; microPET; microPET/CT; microSPECT; molecular imaging; novel; novel therapeutics; operation; optical imaging; pre-clinical; programs; skills; square foot

The Cancer Imaging Shared Resource offers a variety of pre-clinical imaging technologies to image live animal models of cancer. In addition to the broad spectrum of microPET/CT scanners, the shared resource also offers bioluminescence and fluorescence imaging systems, personalized consultations for experimental design and data analysis, and training sessions to provide new users with the skills necessary to meet their cancer research needs. The facility also offers tissue-sectioning facilities, surgery benches, access to ultrasound equipment and optical imaging systems. The shared resource operates under the direction of Timothy C. Doyle, DPhil, who brings years of experience in industry to the operation of the facility. The resource occupies 4180 square feet in four major locations on the Stanford campus and one off-campus, all conveniently located next to animal housing facilities and research laboratories. Three full-time PhD scientists are employed to assist SCI investigators with their imaging needs. The primary imaging facility is located in the Clark Center, and has all the available imaging modalities, including bioluminescence and fluorescence imaging systems, MicroCT scanners, ultrasound and photoacoustic scanners, high-field (7T) MRI, MicroPET/CT and MicroPET scanners, and MicroSPECT/CT scanners. The facility operates on a cost-recovery basis, with ongoing expenses recovered primarily through user fees. The Shared Resource’s annual operating costs are approximately $900,000. Since 2009, over 96 SCI members have used the Shared Resource, with the majority of users coming from the Cancer Imaging and Cancer Stem Cells Programs. Future goals include updating the instruments that are available to users to ensure that the latest technology is available. This includes the replacement of two older MicroSPECT/CT scanners, for which the SCI is contributing resources. The range of imaging modalities in the Lokey barrier imaging facility will also be expanded, since only optical and microPET/CT instruments are currently located in this laboratory.

癌症成像共享资源提供了各种临床前成像技术，以成像癌症的活体动物模型。除了广泛的microPET/CT扫描仪外，共享资源还提供生物发光和荧光成像系统，实验设计和数据分析的个性化咨询，以及培训课程，为新用户提供满足其癌症研究需求所需的技能。该设施还提供组织切片设施，手术台，超声波设备和光学成像系统。 共享资源在Timothy C.多伊尔，博士，谁带来了多年的经验，在行业的运作设施。该资源占地4180平方英尺，位于斯坦福大学校园内的四个主要地点和一个校外，所有这些地点都位于动物饲养设施和研究实验室旁边。聘请了三名全职博士科学家来协助SCI研究人员满足他们的成像需求。主要成像设施位于克拉克中心，拥有所有可用的成像模式，包括生物发光和荧光成像系统，MicroCT扫描仪，超声和光声扫描仪，高场（7 T）MRI，MicroPET/CT和MicroPET扫描仪以及MicroSPECT/CT扫描仪。 该设施在成本回收基础上运作，主要通过使用费回收持续支出。共享资源的年度运营成本约为90万美元。自2009年以来，超过96个SCI成员使用了共享资源，其中大多数用户来自癌症成像和癌症干细胞项目。未来的目标包括更新用户可用的工具，以确保获得最新技术。这包括更换两台较旧的MicroSPECT/CT扫描仪，SCI正在为此提供资源。Lokey屏障成像设施的成像模式范围也将扩大，因为该实验室目前只有光学和微型PET/CT仪器。