2019 Polyamines GRS/GRC
2019 多胺 GRS/GRC
基本信息
- 批准号:9750998
- 负责人:
- 金额:$ 1.2万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-06-01 至 2020-05-31
- 项目状态:已结题
- 来源:
- 关键词:AcademiaAgingAmino AcidsApplications GrantsAreaArginineAsiaAuthorization documentationBacterial InfectionsBasic ScienceBiological ModelsBiologyBiotechnologyBudgetsCancer BiologyCell physiologyChemopreventive AgentClinicalClinical TrialsCollaborationsCommunitiesDL-alpha-DifluoromethylornithineDevelopmentDiabetes MellitusDigestive System DisordersDisciplineDiseaseDrosophila genusEpigenetic ProcessEuropeFosteringFundingGenetic TranscriptionGoalsHost DefenseHourHumanImmune responseImmunologyInfectionInflammationInfusion proceduresInternationalInterventionIon ChannelLeadLearningLifeLinkLocationMalignant NeoplasmsMammalsMetabolic ControlMetabolic DiseasesMetabolismNamesNational Institute of Allergy and Infectious DiseaseNational Institute of Diabetes and Digestive and Kidney DiseasesNatureNeuroblastomaNorth AmericaOrganismOutcomeParasitesParasitic infectionParticipantPathway interactionsPharmacologic SubstancePhysiciansPlantsPlayPolyaminesPreventionProkaryotic CellsRegulationRequest for ProposalsResearchResearch PersonnelRoleRunningScientistSouth AmericaStudentsTranslational ResearchTranslationsTravelUnited States National Institutes of HealthVertebratesWorkbasec newcarcinogenesiscareercareer developmentcostdata exchangeexperiencegraduate studenthuman diseaseinnovationinterestmeetingsmembermicrobiomemultidisciplinarynervous system disordernext generationnovelpathogenpolycationpostersprogramssuccesssymposiumtargeted treatmenttranslational impacttumor
项目摘要
Project Summary.
The Polyamines Gordon Research Conference (GRC) has run continuously since 1975, and provides a
multidisciplinary forum that brings together leading polyamine researchers, as well as young and established
investigators new to the field. The 2019 Polyamines GRC will be held at Waterville Valley Hotel in Waterville
Valley, NH, from June 23-28, 2019. This GRC will have a broad focus on the role of polyamines in human
diseases, with topic areas that include cancer biology, immunology/inflammation, host-pathogen interactions,
digestive diseases, diabetes, neurologic disorders, and many new potential interventions. The meeting is
unique in that it attracts a diverse array of top investigators assessing the control and roles of polyamines
across a broad spectrum of model systems (prokaryotes, parasites, Drosophila, plants, vertebrates, and
mammals). Polyamines are small, amino-acid-derived polycations found in all forms of life and play essential
roles in many cellular processes, including transcription, translation, replication, metabolism, epigenetic control,
and ion channel functions. The 2019 Polyamines GRC will emphasize targeting polyamine pathways in cancer
and other diseases. It will showcase key new links between arginine metabolism and polyamines, and other
metabolic control pathways that can then lead to alterations in host defense against pathogens and tumors,
immune responses leading to inflammation, carcinogenesis, metabolic disorders, neurologic diseases, aging,
and the microbiome. The Program has a strong mix of basic, translational, and clinical researchers. This GRC
is attended by biologists, chemists, and physician-scientists, and includes investigators from academia,
biotech, and pharmaceutical sectors. The diversity of scientific disciplines is unique among GRCs, is highly
stimulating, and will emphasize new findings relating to upstream and downstream pathways, and diseases
only recently linked to alterations in polyamine biology. We will bring the latest studies, new investigators to the
field, and early career investigators to this forum. Of the 26 named speakers, 25 are new since the last GRC
and 18 have never spoken at the GRC; 9 are early career scientists. We will choose 6 speakers from the
Gordon Research Seminar (GRS) and the posters, which will add more new speakers. The specific aims seek
to obtain funds to support 41 GRC and 16 GRS registrations, and travel costs for 16 GRC/GRS participants.
The long-term objective is to enhance understanding of the interplay between polyamine metabolism and
human diseases, and to develop promising young scientists into contributing members of the polyamine
scientific community. Presentations by invited speakers will be 25-30 minutes, with a 10-minute discussion.
The GRC will be held in conjunction with the 7th Polyamines GRS, providing graduate students and fellows
with a student-run venue that fosters exchange of data and ideas. The GRS makes the GRC a richer
experience, promoting participation of young scientists during the main conference. Interactions between GRS
and GRC conferees facilitate sharing of new ideas and create new partnerships that will drive the field forward.
项目总结。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Keith T. Wilson其他文献
1145 EVALUATION OF THE SAFETY AND EFFICACY OF EFLORNITHINE (DIFLUOROMETHYLORNITHINE, DFMO) IN PATIENTS WITH GASTRIC PREMALIGNANT CONDITIONS IN THE HIGH INCIDENCE AREAS OF LATIN AMERICA
- DOI:
10.1016/s0016-5085(24)01098-9 - 发表时间:
2024-05-18 - 期刊:
- 影响因子:
- 作者:
Douglas R. Morgan;Ricardo L. Dominguez;Dalton A. Norwood;Eleazar E. Montalvan-Sanchez;Maria B. Piazuelo;Jessica Hernandez-Marrero;Maria Gonzalez-Pons;Elizabeth Bruckheimer;Mark Beasley;Marcia R. Cruz-Correa;Keith T. Wilson - 通讯作者:
Keith T. Wilson
Mo1146 - <em>Helicobacter Pylori</em> Genetic Ancestry in Central America is Consistent with Disrupted Co-Evolution, with Implications for Gastric Cancer Risk
- DOI:
10.1016/s0016-5085(17)32349-1 - 发表时间:
2017-04-01 - 期刊:
- 影响因子:
- 作者:
Gloria Tavera;Ricardo L. Dominguez;Jacquelaine Bartlett;Barbara G. Schneider;Charlotte Buehler Cherry;Dawn Israel;Judith Romero-Gallo;Robertino M. Mera;M. Blanca Piazuelo;Richard M. Peek;Keith T. Wilson;Scott Williams;Douglas Morgan - 通讯作者:
Douglas Morgan
Cyclosporin a (CsA) induces enhanced leukocyte binding by human intestinal microvascular endothelial cells (HIMEC): A mechanism for therapeutic failure in long term IBD therapy?
- DOI:
10.1016/s0016-5085(00)85346-9 - 发表时间:
2000-04-01 - 期刊:
- 影响因子:
- 作者:
Parvaneh Rafiee;Christopher P. Johnson;Pamela J. Fisher;Thomas H. Lamirand;Mona S. Li;Keith T. Wilson;David G. Binion - 通讯作者:
David G. Binion
125 - Geospatial Analyses Identify a Clustering of Diffuse Gastric Cancers and Related Risk Exposures in Central America
- DOI:
10.1016/s0016-5085(17)30481-x - 发表时间:
2017-04-01 - 期刊:
- 影响因子:
- 作者:
Charlotte Buehler Cherry;Veronica Escamilla;Ricardo L. Dominguez;Barbara G. Schneider;Margaret L. Gulley;Gloria Tavera;Scott Williams;Dawn Israel;M. Blanca Piazuelo;Keith T. Wilson;Richard M. Peek;Michael Emch;Douglas Morgan - 通讯作者:
Douglas Morgan
1077 - <em>Helicobacter Pylori Cag</em><sup>+</sup> Strains Induce Alterations in the <em>In Vivo</em> Epithelial Proteome that are Associated with Progression of Gastric Carcinogenesis
- DOI:
10.1016/s0016-5085(18)31092-8 - 发表时间:
2018-05-01 - 期刊:
- 影响因子:
- 作者:
Jennifer M. Noto;Kristie Lindsey-Rose;Amanda Hachey;Alberto G. Delgado;Judith Romero-Gallo;Barbara G. Schneider;Timothy Cover;Keith T. Wilson;Juan Carlos Roa;M. Blanca Piazuelo;Richard M. Peek - 通讯作者:
Richard M. Peek
Keith T. Wilson的其他文献
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{{ truncateString('Keith T. Wilson', 18)}}的其他基金
BCCMA: Targeting Gut-Microbiome in Veterans Deployment Related Gastrointestinal and Liver Diseases: Dysbiosis, PTSD, and Epithelial and Immune Biology in Inflammatory Bowel Disease in Veterans
BCCMA:针对退伍军人部署相关胃肠道和肝脏疾病的肠道微生物组:退伍军人炎症性肠病中的生态失调、创伤后应激障碍以及上皮和免疫生物学
- 批准号:
10586940 - 财政年份:2023
- 资助金额:
$ 1.2万 - 项目类别:
Spermidine as a New Therapy for Colitis and Chemopreventive for Colitis-associated Carcinogenesis
亚精胺作为结肠炎的新疗法和结肠炎相关癌的化学预防
- 批准号:
10379376 - 财政年份:2021
- 资助金额:
$ 1.2万 - 项目类别:
Spermidine as a New Therapy for Colitis and Chemopreventive for Colitis-associated Carcinogenesis
亚精胺作为结肠炎的新疗法和结肠炎相关癌的化学预防
- 批准号:
10180436 - 财政年份:2021
- 资助金额:
$ 1.2万 - 项目类别:
Spermidine as a New Therapy for Colitis and Chemopreventive for Colitis-associated Carcinogenesis
亚精胺作为结肠炎的新疗法和结肠炎相关癌的化学预防
- 批准号:
10579252 - 财政年份:2021
- 资助金额:
$ 1.2万 - 项目类别:
Dysregulated Polyamine Metabolism in H. pylori-associated Gastric Inflammation and Disease Progression
幽门螺杆菌相关胃炎症和疾病进展中多胺代谢失调
- 批准号:
10196972 - 财政年份:2020
- 资助金额:
$ 1.2万 - 项目类别:
Dysregulated Polyamine Metabolism in H. pylori-associated Gastric Inflammation and Disease Progression
幽门螺杆菌相关胃炎症和疾病进展中多胺代谢失调
- 批准号:
10620757 - 财政年份:2020
- 资助金额:
$ 1.2万 - 项目类别:
Dysregulated Polyamine Metabolism in H. pylori-associated Gastric Inflammation and Disease Progression
幽门螺杆菌相关胃炎症和疾病进展中多胺代谢失调
- 批准号:
10572035 - 财政年份:2020
- 资助金额:
$ 1.2万 - 项目类别:
Immunomodulatory effects of arginine supplementation in colitis and colon cancer
补充精氨酸对结肠炎和结肠癌的免疫调节作用
- 批准号:
8857372 - 财政年份:2013
- 资助金额:
$ 1.2万 - 项目类别:
Immunomodulatory effects of arginine supplementation in colitis and colon cancer
补充精氨酸对结肠炎和结肠癌的免疫调节作用
- 批准号:
8690770 - 财政年份:2013
- 资助金额:
$ 1.2万 - 项目类别:
Immunomodulatory effects of arginine supplementation in colitis and colon cancer
补充精氨酸对结肠炎和结肠癌的免疫调节作用
- 批准号:
9300834 - 财政年份:2013
- 资助金额:
$ 1.2万 - 项目类别:
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