COBRE in CV Health Administrative Core

项目总结/摘要 心血管疾病（CVD），如心脏病，心力衰竭和中风影响特拉华州的速度 远远高于全国平均水平。在此申请中，我们寻求建立一个生物医学中心， 卓越的心血管健康研究，可以与更大的区域临床和研究接口 使命，并积极影响我们地区人口的心血管健康。这个中心将催化 心血管健康研究，通过培养一个新的子项目团队的独立研究事业， 研究人员，加强研究基础设施和能力，进行心血管健康研究， 建立核心设施，以提高五个分项目主要研究人员的研究能力 和中心的其他成员，并建立一个可持续的心血管健康研究中心。的 COBRE管理核心的总体目标是最大限度地提高每个部门的生产力和影响力， 通过有效的管理、指导和职业生涯， 中心的发展、评估和扩建。这将通过以下方式实现：1）建立有效的 管理拟议的COBRE的行政、财政和科学方面; 2）建立一个 有效的指导和职业发展计划，以促进独立的研究职业分项目新 调查员; 3）通过以下方式监测拟议的COBRE向里程碑的进展情况： 实施总结性和形成性评价; 4）通过试点赠款扩大中心， 新的研究人员和有针对性地招聘具有心血管健康专业知识的研究人员。 行政核心概述了一个领导计划，其中包括PI，内部咨询委员会， 评估员和一个即将成立的外部咨询委员会。一个指导计划，补充了 描述了发生在特拉华州大学的正在进行的指导。毕业和替换计划 还概述了次级项目调查员。

PROJECT SUMMARY/ABSTRACT Cardiovascular diseases (CVD) such as heart disease, heart failure, and stroke affect Delawareans at a rate significantly above the national average. In this application, we seek to establish a Center of Biomedical Research Excellence in Cardiovascular Health that can interface with the larger regional clinical and research mission and positively impact the cardiovascular health of our regional populations. This center will catalyze cardiovascular health research by fostering the independent research careers of a team of subproject new investigators, strengthen the research infrastructure and capacity to perform cardiovascular health research by establishing core facilities that will enhance the research capability of the five subproject principal investigators and other members of the Center, and develop a sustainable research center in cardiovascular health. The overall goal of the COBRE administrative core is to maximize the productivity and impact of each of the subprojects, core, and the center as a whole through effective management, mentoring and career development, evaluation, and expansion of the center. This will be accomplished by: 1) establishing effective management of administrative, fiscal, and scientific aspects of the proposed COBRE; 2) establishing an effective mentoring and career development plan to foster the independent research careers subproject new investigators; 3) monitoring the progress of the proposed COBRE toward milestones through the implementation of summative and formative evaluations; and 4) expanding the center through pilot grants to new investigators and targeted recruitment of research faculty with expertise in cardiovascular health. The administrative core outlines a leadership plan that includes the PI, an Internal Advisory Committee, an evaluator, and a to-be-formed External Advisory Committee. A mentoring program that complements the ongoing mentoring that occurs at the University of Delaware is described. Plans for graduating and replacing subproject investigators are also outlined.