HIV prevention among Latina transgender women who have sex with men: Evaluation of a locally developed intervention

男男性行为拉丁裔跨性别女性的艾滋病毒预防：对当地制定的干预措施的评估

• 批准号: 9753065
• 负责人: Scott D Rhodes
• 金额: $ 40万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-30 至 2020-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9753065
• 关键词: HIV; prevention; among; Latina; transgender

Project Summary The United States has a large and rapidly growing Latino population. At the same time, Latinos and transgender persons in the US carry disproportionate HIV burden. Currently, no efficacious HIV prevention interventions exist for transgender persons who have sex with men. In response to RFA-PS-16-003 “Evaluating Locally-Developed or Adapted (Homegrown) Combination HIV Prevention Interventions for Transgender Persons who have Sex with Men”, our community-university partnership proposes a 4-year study (U01) to refine, fully implement, and rigorously evaluate a small-group combination intervention designed to promote behavioral, biomedical, and social/structural approaches to HIV prevention by increasing condom use, HIV testing, PrEP use, and use of safe transition-related healthcare services among Latina transgender women who have sex with men. The intervention, known as Chicas Creando Acceso a la Salud (ChiCAS; Girls Creating Access to Health), was developed locally by a community-based organization, in partnership with Latina transgender women, and is informed by social cognitive theory and theory of empowerment education. Although data suggest that ChiCAS is promising, it has not yet been evaluated. The proposed study is a result of a well-established community-university partnership. A total of 100 Latina transgender women who have sex with men will be enrolled. Participants will complete an initial baseline assessment designed to measure current sexual health behaviors, healthcare use, and psychological, social, and cultural influences on sexual behaviors and healthcare use. Participants then will be randomized to the 4- session small-group combination HIV prevention intervention group or a delayed-intervention comparison group (waitlist). All participants also will complete identical assessments at 3-month and 6-month follow-up. Participants in the HIV prevention intervention, relative to their peers in the delayed-intervention comparison group, are anticipated to demonstrate (a) increased self-reported use of condoms during sexual intercourse; (b) increased HIV testing; (c) increased use of PrEP; and (d) increased use of safe transition-related healthcare services (including medical care and mental health services). The results and products from this study will be disseminated to inform public health practice, research, and policy. Results and products will include: (1) a Spanish-language combination small-group HIV prevention intervention that is: culturally congruent, designed to reduce risk among Latina transgender women, and ready for dissemination and further implementation if found to be efficacious; and (2) a deeper understanding of HIV risk, use of transition-related healthcare services, and intervention among Latina transgender women.

项目摘要 美国拥有大量且快速增长的拉丁裔人口。与此同时，拉美裔和 美国的跨性别者承担着不成比例的艾滋病毒负担。目前，尚无有效的艾滋病毒预防措施 对与男子发生性关系的变性人采取了干预措施。响应RFA-PS-16-003 “评价当地开发或改编（本土）的艾滋病毒预防综合干预措施， 与男性发生性关系的变性人”，我们的社区-大学合作伙伴关系提出了一项为期4年的研究 (U01)完善、全面实施和严格评估小组组合干预， 通过增加安全套的使用，促进行为、生物医学和社会/结构方法预防艾滋病毒， 艾滋病毒检测，PrEP使用，以及拉丁裔变性人使用安全过渡相关的医疗服务 和男人发生性关系的女人这项干预措施被称为ChiCAS;女孩 创造健康的机会），由一个社区组织与 拉丁裔变性妇女，并告知社会认知理论和赋权教育理论。 虽然数据表明ChiCAS是有前途的，但尚未进行评估。 拟议的研究是一个建立良好的社区-大学伙伴关系的结果。共100名拉丁裔 与男性发生性关系的变性妇女将被录取。参与者将完成初始基线 评估旨在衡量当前的性健康行为，医疗保健使用，以及心理，社会， 以及文化对性行为和医疗保健使用的影响。然后，参与者将被随机分配至4- 届小团体联合艾滋病预防干预组或延迟干预组比较 组（waitlist）。所有参与者还将在3个月和6个月随访时完成相同的评估。 参与艾滋病预防干预的人员，相对于其同龄人的延迟干预比较 预计将显示（a）性交时自我报告使用避孕套的人数增加; (b)增加艾滋病毒检测;（c）增加使用PrEP;（d）增加使用安全过渡相关的 保健服务（包括医疗保健和心理健康服务）。由此产生的结果和产品 将传播研究结果，为公共卫生实践、研究和政策提供信息。结果和产品将 包括：（1）西班牙语混合小组艾滋病毒预防干预，即：文化上 一致，旨在减少拉丁裔变性妇女的风险，并准备传播和进一步 实施，如果发现是有效的;和（2）更深入地了解艾滋病毒的风险，使用过渡相关的 医疗保健服务和拉丁裔跨性别妇女的干预。