2019 Amygdala Function in Emotion, Cognition and Disease GRS/GRC

项目摘要 杏仁核在情绪，认知和疾病戈登研究会议（GRC）是第七届 为期五天的会议的两年期分期付款定于2019年8月4日至9日在斯通希尔学院，伊斯顿 马萨诸塞州，由凯泰和托马斯卡什主持。杏仁核被认为是 大脑系统中的一个节点，负责一系列在各种心理活动中受到干扰的高级行为 紊乱因此，会议的重点反映了精神病学正在进行的转变， 神经回路功能异常的精神疾病。目标是：（1）促进跨部门的互动 学科（从基础发现研究到转化研究）， 杏仁核介导高级行为和精神疾病状态，特别是那些特征为 成瘾和焦虑，2）突出重要的新工具和技术，可能适用于研究的 杏仁核，希望开辟新的科学问题和研究途径，和3）指导一个新的 一代科学家和科学家临床医生，特别是妇女和少数群体，在一个高度 支持性和包容性的环境。 会议将以一个由神经科学先驱的两个全体演讲组成的主题演讲开始 (BJ凯西和理查德帕尔米特），选择带来他们独特的和权威的观点，对国家的 外地在接下来的四天里，共有十二场会议，每一场都有一个专门的主题， 在成瘾、情绪和认知研究领域，来自世界知名领导者的口头报告。此外 他们在该领域的地位，我们选择发言者的重要标准是，他们代表了一个 跨学科的科学广度以及性别和国籍的多样性。 在GRC之前将有一个GRS，这是一个独特的为期两天的研究生论坛，博士后和其他 年轻科学家展示和交流新数据和前沿想法。对杏仁核的兴趣， 已知在情绪和奖励过程中起关键作用的结构，近年来大大增加 年事实上，在杏仁核可塑性机制中有明显的重叠，这些机制被发现是适应不良的， 例如，药物滥用和焦虑的模型。会议的一个中心目标是将成瘾和 奖励相关的工作到这个GRC的永久结构，包括一个主题演讲和一些 明确关注这些研究领域的会议，NIDA和NIAAA资助的领导人在 滥用和成瘾的科学

PROJECT SUMMARY The Amygdala Function in Emotion, Cognition & Disease Gordon Research Conference (GRC) is the seventh biennial installment of a five-day meeting scheduled for August 4-9, 2019 at Stonehill College, Easton Massachusetts, to be chaired by Kay Tye and Thomas Kash. The amygdala has been identified as a central node within brain systems subserving an array of higher-order behaviors that are disturbed in various mental disorders. Thus, the focus of the meeting reflects on ongoing shift in psychiatry towards framing the study of mental illness in terms of aberrant neural circuit functions. The aims are 1) to foster interactions across disciplines (from basic discovery research to translational research) related to understanding the role of the amygdala in mediating higher-order behaviors and mental disease states, particularly those characterized by addiction & anxiety, 2) to highlight important new tools and techniques that may be applied to the study of the amygdala, with the hope of opening new scientific questions and avenues of research, and 3) to mentor a new generation of scientists and scientist-clinicians, particularly women and those from minority groups, in a highly supportive and inclusive setting. The meeting will open with a Keynote session consisting of two plenary lectures by pioneers in neuroscience (BJ Casey, and Richard Palmiter), selected to bring their unique and authoritative perspectives on the state of the field. Over the next four days, there will be a total of twelve sessions, each on a dedicated theme, featuring oral presentations from recognized world-leaders in the study of addiction, emotion, and cognition. In addition to their status in the field, important criteria for our selection of speakers is that they represent an interdisciplinary scientific breadth and a diversity in gender and nationality. The GRC will be preceded by a GRS, a unique two-day forum for graduate students, post-docs, and other junior scientists to present and exchange new data and cutting edge ideas. Interest in the amygdala, a brain structure known to play a pivotal role in emotional and reward processes, has increased considerably in recent years. Indeed, there is marked overlap in the amygdala plasticity mechanisms found to be maladaptive in models of, for example, drug abuse and anxiety. A central goal of the meeting is to integrate addiction and reward related work into the permanent fabric of this GRC by including a keynote lecture and a number of the sessions that explicitly focus on these areas of research, with talks from NIDA and NIAAA funded leaders in the science of abuse and addiction.