2019 Amygdala Function in Emotion, Cognition and Disease GRS/GRC
2019 杏仁核在情绪、认知和疾病中的功能 GRS/GRC
基本信息
- 批准号:9758948
- 负责人:
- 金额:$ 1.5万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-05-15 至 2020-04-30
- 项目状态:已结题
- 来源:
- 关键词:Amygdaloid structureAnxietyAreaBasic ScienceBehaviorBrainClinicalClinical ResearchCognitionCollaborationsDataDisciplineDiseaseDrug abuseElementsEmotionalEmotionsEnsureFertilizationFosteringFundingFutureGenderGenerationsGoalsHourLeadershipMassachusettsMediatingMental disordersMentorsMinority GroupsModelingMolecularNational Institute of Drug AbuseNational Institute on Alcohol Abuse and AlcoholismNationalitiesNeurosciencesNurseriesOralParticipantPathologicPlayPost-Traumatic Stress DisordersPostdoctoral FellowProcessPsyche structurePsychiatryResearchResearch PersonnelRewardsRodent ModelRoleScheduleScienceScientistStructureSubstance Use DisorderSystemTechniquesTextilesTimeTrainingTranslatingTranslational ResearchWomanWorkaddictionautism spectrum disorderbasebrain behaviorcollegeconditioned feargraduate studentinnovationinterestlecturesmeetingsneural circuitnext generationnovelpostersprofessorprogramspsychobiologyrelating to nervous systemreward processingsymposiumsynergismtooltraining opportunityunpublished works
项目摘要
PROJECT SUMMARY
The Amygdala Function in Emotion, Cognition & Disease Gordon Research Conference (GRC) is the seventh
biennial installment of a five-day meeting scheduled for August 4-9, 2019 at Stonehill College, Easton
Massachusetts, to be chaired by Kay Tye and Thomas Kash. The amygdala has been identified as a central
node within brain systems subserving an array of higher-order behaviors that are disturbed in various mental
disorders. Thus, the focus of the meeting reflects on ongoing shift in psychiatry towards framing the study of
mental illness in terms of aberrant neural circuit functions. The aims are 1) to foster interactions across
disciplines (from basic discovery research to translational research) related to understanding the role of the
amygdala in mediating higher-order behaviors and mental disease states, particularly those characterized by
addiction & anxiety, 2) to highlight important new tools and techniques that may be applied to the study of the
amygdala, with the hope of opening new scientific questions and avenues of research, and 3) to mentor a new
generation of scientists and scientist-clinicians, particularly women and those from minority groups, in a highly
supportive and inclusive setting.
The meeting will open with a Keynote session consisting of two plenary lectures by pioneers in neuroscience
(BJ Casey, and Richard Palmiter), selected to bring their unique and authoritative perspectives on the state of
the field. Over the next four days, there will be a total of twelve sessions, each on a dedicated theme, featuring
oral presentations from recognized world-leaders in the study of addiction, emotion, and cognition. In addition
to their status in the field, important criteria for our selection of speakers is that they represent an
interdisciplinary scientific breadth and a diversity in gender and nationality.
The GRC will be preceded by a GRS, a unique two-day forum for graduate students, post-docs, and other
junior scientists to present and exchange new data and cutting edge ideas. Interest in the amygdala, a brain
structure known to play a pivotal role in emotional and reward processes, has increased considerably in recent
years. Indeed, there is marked overlap in the amygdala plasticity mechanisms found to be maladaptive in
models of, for example, drug abuse and anxiety. A central goal of the meeting is to integrate addiction and
reward related work into the permanent fabric of this GRC by including a keynote lecture and a number of the
sessions that explicitly focus on these areas of research, with talks from NIDA and NIAAA funded leaders in
the science of abuse and addiction.
项目摘要
杏仁核在情绪,认知和疾病戈登研究会议(GRC)是第七届
为期五天的会议的两年期分期付款定于2019年8月4日至9日在斯通希尔学院,伊斯顿
马萨诸塞州,由凯泰和托马斯卡什主持。杏仁核被认为是
大脑系统中的一个节点,负责一系列在各种心理活动中受到干扰的高级行为
紊乱因此,会议的重点反映了精神病学正在进行的转变,
神经回路功能异常的精神疾病。目标是:(1)促进跨部门的互动
学科(从基础发现研究到转化研究),
杏仁核介导高级行为和精神疾病状态,特别是那些特征为
成瘾和焦虑,2)突出重要的新工具和技术,可能适用于研究的
杏仁核,希望开辟新的科学问题和研究途径,和3)指导一个新的
一代科学家和科学家临床医生,特别是妇女和少数群体,在一个高度
支持性和包容性的环境。
会议将以一个由神经科学先驱的两个全体演讲组成的主题演讲开始
(BJ凯西和理查德帕尔米特),选择带来他们独特的和权威的观点,对国家的
外地在接下来的四天里,共有十二个会议,每个会议都有一个专门的主题,
在成瘾、情绪和认知研究领域,来自世界知名领导者的口头报告。此外
他们在该领域的地位,我们选择发言者的重要标准是,他们代表了一个
跨学科的科学广度以及性别和国籍的多样性。
在GRC之前将有一个GRS,这是一个独特的为期两天的研究生论坛,博士后和其他
年轻科学家展示和交流新数据和前沿想法。对杏仁核的兴趣,
已知在情绪和奖励过程中起关键作用的结构,近年来大大增加
年事实上,在杏仁核可塑性机制中有明显的重叠,这些机制被发现是适应不良的,
例如,药物滥用和焦虑的模型。会议的一个中心目标是将成瘾和
奖励相关的工作到这个GRC的永久结构,包括一个主题演讲和一些
明确关注这些研究领域的会议,NIDA和NIAAA资助的领导人在
滥用和成瘾的科学
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Thomas L. Kash其他文献
Withdrawal from chronic intermittent ethanol engages a circuit in the bed nucleus of the stria terminalis that promotes anxiety and fear-related behavior
- DOI:
10.1016/j.alcohol.2017.02.354 - 发表时间:
2017-05-01 - 期刊:
- 影响因子:
- 作者:
Catherine A. Marcinkiewcz;Dipanwita Pati;Jeffrey F. Diberto;Thomas L. Kash - 通讯作者:
Thomas L. Kash
A dual-virus strategy for the deletion of cacan1c within the prelimbic to nucleus accumbens core projection
用于在前边缘至伏隔核核心投射内删除 cacan1c 的双病毒策略
- DOI:
10.1038/s41380-020-00886-1 - 发表时间:
2020-09-24 - 期刊:
- 影响因子:10.100
- 作者:
Charlotte C. Bavley;Robert N. Fetcho;Caitlin E. Burgdorf;Alexander P. Walsh;Delaney K. Fischer;Baila S. Hall;Nicole M. Sayles;Natalina H. Contoreggi;Jonathan E. Hackett;Susan A. Antigua;Rachel Babij;Natalia V. De Marco García;Thomas L. Kash;Teresa A. Milner;Conor Liston;Anjali M. Rajadhyaksha - 通讯作者:
Anjali M. Rajadhyaksha
Corticotropin-Releasing Factor Modulates Binge-Like Ethanol Drinking in a Sex-Dependent Manner: Impact of Amygdala Deletion and Inhibition of a Central Amygdala to Lateral Hypothalamus Circuit
- DOI:
10.1016/j.bpsgos.2024.100405 - 发表时间:
2025-01-01 - 期刊:
- 影响因子:
- 作者:
Sophie C. Bendrath;Hernán G. Méndez;Anne M. Dankert;Jose Manuel Lerma-Cabrera;Francisca Carvajal;Ana Paula S. Dornellas;Sophia Lee;Sofia Neira;Harold Haun;Eric Delpire;Montserrat Navarro;Thomas L. Kash;Todd E. Thiele - 通讯作者:
Todd E. Thiele
RETRACTED ARTICLE: Predator odor increases avoidance and glutamatergic synaptic transmission in the prelimbic cortex via corticotropin-releasing factor receptor 1 signaling
撤回文章:捕食者气味通过促肾上腺皮质激素释放因子受体 1 信号通路增加前边缘皮层的回避行为和谷氨酸能突触传递
- DOI:
10.1038/s41386-018-0279-2 - 发表时间:
2018-11-23 - 期刊:
- 影响因子:7.100
- 作者:
Lara S. Hwa;Sofia Neira;Melanie M. Pina;Dipanwita Pati;Rachel Calloway;Thomas L. Kash - 通讯作者:
Thomas L. Kash
A distinct cortical code for socially learned threat
用于社会学习到的威胁的一种独特皮质编码
- DOI:
10.1038/s41586-023-07008-1 - 发表时间:
2024-02-07 - 期刊:
- 影响因子:48.500
- 作者:
Shana E. Silverstein;Ruairi O’Sullivan;Olena Bukalo;Dipanwita Pati;Julia A. Schaffer;Aaron Limoges;Leo Zsembik;Takayuki Yoshida;John J. O’Malley;Ronald F. Paletzki;Abby G. Lieberman;Mio Nonaka;Karl Deisseroth;Charles R. Gerfen;Mario A. Penzo;Thomas L. Kash;Andrew Holmes - 通讯作者:
Andrew Holmes
Thomas L. Kash的其他文献
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{{ truncateString('Thomas L. Kash', 18)}}的其他基金
Dietary choline mitigation of adolescent alcohol-induced deficits in adult cognitive flexibility: P60-AA011605 Administrative Supplement
膳食胆碱缓解青少年酒精引起的成人认知灵活性缺陷:P60-AA011605 行政补充
- 批准号:
10330051 - 财政年份:2021
- 资助金额:
$ 1.5万 - 项目类别:
Determining the impact of BNST CRF systems on inflammatory pain-induced disruptions of behavior
确定 BNST CRF 系统对炎性疼痛引起的行为破坏的影响
- 批准号:
10386925 - 财政年份:2021
- 资助金额:
$ 1.5万 - 项目类别:
Determining the impact of BNST CRF systems on inflammatory pain-induced disruptions of behavior
确定 BNST CRF 系统对炎性疼痛引起的行为破坏的影响
- 批准号:
10608985 - 财政年份:2021
- 资助金额:
$ 1.5万 - 项目类别:
Dissecting the role of ethanol-induced plasticity in the PAG to BNST pathway in pain-related behaviors
剖析乙醇诱导的可塑性在 PAG 至 BNST 通路中在疼痛相关行为中的作用
- 批准号:
9763786 - 财政年份:2019
- 资助金额:
$ 1.5万 - 项目类别:
Dissecting the role of ethanol-induced plasticity in the PAG to BNST pathway in pain-related behaviors
剖析乙醇诱导的可塑性在 PAG 至 BNST 通路中在疼痛相关行为中的作用
- 批准号:
9926793 - 财政年份:2019
- 资助金额:
$ 1.5万 - 项目类别:
The role of corticotropin releasing factor in binge-like ethanol drinking
促肾上腺皮质激素释放因子在酗酒中的作用
- 批准号:
10444006 - 财政年份:2013
- 资助金额:
$ 1.5万 - 项目类别:
The role of corticotropin releasing factor in binge-like ethanol drinking
促肾上腺皮质激素释放因子在酗酒中的作用
- 批准号:
10600068 - 财政年份:2013
- 资助金额:
$ 1.5万 - 项目类别:
Chronic Alcohol Induced Dysregulation of Central Anti-Stress Systems
慢性酒精引起中枢抗应激系统失调
- 批准号:
8423705 - 财政年份:2012
- 资助金额:
$ 1.5万 - 项目类别:
5/8 INIA Stress and Chronic Alcohol Interactions: Probing brain circuits that regulate alcohol stress interactions
5/8 INIA 压力和慢性酒精相互作用:探索调节酒精压力相互作用的大脑回路
- 批准号:
10574573 - 财政年份:2012
- 资助金额:
$ 1.5万 - 项目类别:
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