2019 Second International Fetal Heart Symposium

摘要 本申请申请资助2019第二届国际胎儿心脏 研讨会活动定于4月25日至27日举行。2019年。本次研讨会的主题包括 对于胎儿心脏，新的成像方式和新的进展，如干细胞移植 先天性心脏缺陷。它的重点是提高对心脏背后的遗传病因的理解 缺陷，了解胎儿心脏形成的机制，新成像的应用 早期发现心脏缺陷的方法和组织工程学的应用 改善手术结果的技术，特别是在单心室修复中。 先天性心脏病(CHD)是胎儿最常见的结构异常 发病率为6-8/1000。冠心病的病因可分为遗传因素和环境因素 因素和大多数研究表明，它可能是多因素的。尽管如此，70%的冠心病 发生的原因不明。众所周知，产前对冠心病的检测可以改善 出生后的结局；因此，宫内诊断对计划怀孕很重要。因为 围产期医学是一个多学科的领域，研讨会的目标是汇聚基础知识 科学家、放射学家、超声学家、遗传学家、围产期专家、儿科心脏病专家、心脏病专家 外科医生、医学生和护士讨论筛查方法、早期发现、新的 成像方式和结果的改善。 拟议的2.5天研讨会包括有组织的教学会议和促进会议 学习。这次研讨会的六个具体目标是：1)展示改进的实践 关于先天性心脏病的重要概念的战略。2)定义 成像技术的进步。3)表现出更强的诊断能力和 胎儿心脏异常的处理。4)描述筛查的最新进展， 先天性心脏病的诊断和治疗。5)描述最相关的额外内容 心脏畸形和心脏缺陷，并学习如何在产前管理孕妇。 6)展示主要心脏的出生后管理和干细胞治疗的新进展 缺陷。 演讲者将包括高级调查人员，他们在各自的胎儿和 儿科心脏病学、遗传学和心脏外科。实践部分将讨论实际问题 胎儿超声心动图的应用技巧及对不同多普勒模式的认识 心功能评估。

SUMMARY This application requests funds for support of the 2019 Second International Fetal Heart Symposium event scheduled for April 25-27. 2019. This Symposium encompasses topics related to fetal heart, new imaging modalities and new advances such as stem cell transplantation in congenital heart defects. Its focus is to improve understanding the genetic etiology behind heart defects, understanding the mechanisms of fetal heart formation, application of new imaging modalities to detect heart defects as early as possible and application of tissue engineering techniques to improve surgical outcomes, especially in single ventricular repair. Congenital heart defects (CHD) are the most common structural abnormalities in the fetus with an incidence of 6-8/1000. The etiology of CHD can be divided into genetic and environmental factors and most of the studies indicate that it could be multifactorial. In spite of that, 70% of CHD occur for unknown reasons. It is very well known that prenatal detection of CHD improves postnatal outcomes; therefore, diagnosis in utero is important to plan the pregnancy. Because perinatal medicine is a multidisciplinary field, the goal of the Symposium is to bring together basic scientists, radiologists, sonographers, geneticists, perinatologists, pediatric cardiologists, cardiac surgeons, medical students, and nurses to discuss the screening methods, early detection, new imaging modalities and improvements in outcomes. The proposed 2.5 day Symposium includes organized didactic sessions and facilitative learning. The six specific goals of this symposium are: 1) Demonstrate improved practice strategies regarding the important concepts of congenital heart disease. 2) Define the advancements in imaging technology. 3) Demonstrate greater competence in the diagnosis and management of fetal cardiac abnormalities. 4) Describe the latest advances in screening, diagnosing and treatment of congenital heart diseases. 5) Describe the most associated extra cardiac anomalies along with heart defects and learn how to manage pregnant women prenatally. 6) Demonstrate new advances in postnatal management and stem cell therapy in major cardiac defects. Speakers will include senior investigators, well established in their fields of fetal and pediatric cardiology, genetics and cardiac surgery. The Hands-on session will address practical tips of fetal echocardiography application, and understanding the different Doppler modalities in assessments of cardiac function.