The role of area V4 in the perception and recognition of visual objects
V4区在视觉物体感知和识别中的作用
基本信息
- 批准号:9759575
- 负责人:
- 金额:$ 59.72万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2009
- 资助国家:美国
- 起止时间:2009-04-01 至 2024-03-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAffectAge related macular degenerationAgnosiaAnimal BehaviorAnimalsAreaAttentionBehaviorBehavior ControlBehavioralBehavioral ParadigmBrain DiseasesBrain regionChildClutteringsCommunicationCommunication impairmentComputer SimulationCrowdingDataDiagnosisDiscriminationDiseaseElectrodesEnvironmentExhibitsFeedbackFunctional disorderHumanImageImpairmentIndividualMethodsModelingMonkeysNeuronsPathway interactionsPatientsPerceptionPerformancePopulationPrefrontal CortexPrimatesProcessPsychophysicsResolutionRoleSensoryShapesStimulusStructureSymptomsTextureTimeV2 neuronV4 neuronVisionVisualVisual CortexVisual PathwaysVisual system structureWorkarea V2area V4attentional controlautism spectrum disorderawakebasebehavior influencedesignexperimental studyextrastriate visual cortexfovea centralisfrontal lobehuman subjectinattentional blindnessinsightneurophysiologyobject recognitionreceptive fieldresponsestatisticstrendvisual stimulus
项目摘要
ABSTRACT
In cluttered natural visual environments object recognition capacity can be severely limited. This may reflect
limitations associated with the visual cortical encoding of multiple nearby stimuli. Alternatively, poor object
recognition in clutter, especially profound in patients with autism, may result from limited resolution of
attentional control and object decoding that rely on interactions between visual cortex and frontal cortex. We
do not know what neuronal mechanisms limit object recognition in crowded scenes because
neurophysiological studies typically present one or two stimuli at a time, and are thus free from the constraints
imposed by clutter in natural scenes. In addition, studies seldom investigate the role of visual-frontal
interactions in object recognition. We will use a combination of single neuron studies in awake monkeys,
behavioral manipulations, reversible inactivation and computational modelling in two mid-level stages of visual
cortex, V2 and V4, and the prefrontal cortex (PFC), to determine: (Aim 1) how V2 and V4 neurons encode
visual stimuli in the presence of clutter, and how the encoding depends on eccentricity and on attentional
engagement; (Aim 2) how PFC feedback influences encoding in V2 and V4, and how these brain regions
together contribute to shape discrimination in clutter. We will consider three hypotheses. First, visual encoding
may have limited resolution in clutter: when many objects are nearby, regardless of what those objects are, the
visual system may fail to segment and encode individual objects. Second, processing in mid-level stages may
be designed to encode only salient objects, i.e., objects that exhibit sufficient feature contrast relative to
neighboring image regions. In this case, loss of information may pertain to objects in homogeneous image
regions reflecting a representational strategy to preferentially encode objects that stand out. Third, it is possible
that all objects are segmented and encoded faithfully, even in clutter, but the capacity limits are dictated by the
resolution of attention or other downstream processes that influence object decoding. Our studies will address
a fundamental gap in the understanding of how multi-objects displays, which dominate natural vision, are
encoded in mid-level visual cortex. They will reveal how encoding strategies vary across eccentricity and this
could be relevant for diseases like age-related macular degeneration, where foveal representations are
compromised selectively. Finally, our results will provide fundamental insights into how V4 and PFC
communication is critical for object recognition in clutter and how diminished communication between the two
could influence behavior. This could be important for guiding translational work on autism spectrum disorder.
摘要
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Anitha Pasupathy其他文献
Anitha Pasupathy的其他文献
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{{ truncateString('Anitha Pasupathy', 18)}}的其他基金
Spatiotemporal representation in ventral visual pathway
腹侧视觉通路的时空表征
- 批准号:
10331833 - 财政年份:2021
- 资助金额:
$ 59.72万 - 项目类别:
Spatiotemporal representation in ventral visual pathway
腹侧视觉通路的时空表征
- 批准号:
10525256 - 财政年份:2021
- 资助金额:
$ 59.72万 - 项目类别:
CRCNS: Joint coding of shape and texture in the primate brian
CRCNS:灵长类动物布莱恩形状和纹理的联合编码
- 批准号:
9765318 - 财政年份:2018
- 资助金额:
$ 59.72万 - 项目类别:
CRCNS: Joint coding of shape and texture in the primate brian
CRCNS:灵长类动物布莱恩形状和纹理的联合编码
- 批准号:
9692119 - 财政年份:2018
- 资助金额:
$ 59.72万 - 项目类别:
NEURAL BASIS OF SHAPE REPRESENTATION AND RECOGNITION
形状表示和识别的神经基础
- 批准号:
8357589 - 财政年份:2011
- 资助金额:
$ 59.72万 - 项目类别:
NEURAL BASIS OF SHAPE REPRESENTATION AND RECOGNITION
形状表示和识别的神经基础
- 批准号:
8172747 - 财政年份:2010
- 资助金额:
$ 59.72万 - 项目类别:
The role of area V4 in the perception and recognition of visual objects
V4区在视觉物体感知和识别中的作用
- 批准号:
8893671 - 财政年份:2009
- 资助金额:
$ 59.72万 - 项目类别:
NEURAL BASIS OF SHAPE REPRESENTATION AND RECOGNITION
形状表示和识别的神经基础
- 批准号:
7958851 - 财政年份:2009
- 资助金额:
$ 59.72万 - 项目类别:
Role of area V4 in the perception of partially occluded objects
V4 区在部分遮挡物体感知中的作用
- 批准号:
8247844 - 财政年份:2009
- 资助金额:
$ 59.72万 - 项目类别:
Role of area V4 in the perception of partially occluded objects
V4 区在部分遮挡物体感知中的作用
- 批准号:
8448292 - 财政年份:2009
- 资助金额:
$ 59.72万 - 项目类别:
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