Technology assisted treatment for trichotillomania

技术辅助治疗拔毛癖

• 批准号: 9622448
• 负责人: Sameer Kumar
• 金额: $ 19.92万
• 依托单位: HABITAWARE, INC.
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-06-21 至 2020-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9622448
• 关键词: Address; Adult; Algorithms; Articular Range of Motion; Awareness; Behavior; Behavior Therapy; Catalogs; Data; Detection; Device or Instrument Development; Devices; Disease; Educational process of instructing; Elements; Ensure; Evidence based intervention; Excision; Eyebrow structure; Feedback; Focus Groups; Gestures; Goals; Habits; Hair; Human; Impairment; Individual; Methods; Motion; Motivation; National Institute of Mental Health; Occupational; Outcome; Patients; Pattern; Persons; Pharmacology; Phase; Play; Process; Protocols documentation; Public Health; Randomized Controlled Trials; Research; Self-Administered; Strategic Planning; Surveys; System; Technology; Testing; Therapeutic; Therapeutic Effect; Thinness; Time; Training; Treatment Efficacy; Trichotillomania; Variant; Well in self; Wood material; Wrist; base; comparison group; cost; design; effective therapy; efficacy study; improved; mobile application; novel; pilot trial; psychologic; response; sensor; smartphone Application; social; success; usability; user-friendly

Abstract Significance: Trichotillomania (TTM), characterized by repeated pulling of one’s hair to the point of hair loss or thinning, produces impairment in physical, social, psychological and occupational functioning. Empirically supported treatment options for those with TTM are seriously limited. Among treatments shown to be effective is behavior therapy. Unfortunately, behavior therapy is limited in that developing real-time awareness of pulling remains challenging, there is a lack of widespread availability, and it typically has high cost. Hypothesis: It is hypothesized that a novel wrist-worn device and app system can be used to deliver Habit Reversal Therapy, a key component of behavior therapy, for trichotillomania. The device, using sophisticated motion sensors and algorithms, can be trained to detect an individual’s pulling behavior and thus augment awareness in real-time. Further, it can detect a competing response and build motivation via a user-friendly, feature rich mobile application. Preliminary Data: The investigative team’s device can record and detect a motion and orientation, representative of hair pulling behavior, reliably, per machine testing. Additionally, in one individual, a behavior of playing with eyebrows was reliably detected in >90% of cases with an acceptable rate (30%) of false positives for similar behaviors. Specific Aim 1: The ability of the device to accurately detect TTM-related behavior will be established and validated. The team will (1) catalog and record the range of motions that go into TTM-related pulling, and (2) refine and test the capacity of the device to accurately detect the motions in both simulated and human tests Specific Aim 2: Develop the HabitAware device and accompanying app as a stand-alone system for delivering self-administered HRT, utilizing an iterative process informed by expert end-user clinicians and persons with TTM. Specific Aim 3: The team will conduct an initial feasibility, usability and acceptability test of the HabitAware device to determine next steps and progress to a Phase II proposal. Long-Term Goal: We aim to develop a user-friendly, widely accessible and affordable system that helps treat trichotillomania via a device that provides real-time awareness of pulling behavior and a mobile app that incorporates elements of existing behavior therapy protocols.

抽象的 意义：拔毛癖（TTM），其特征是反复将某人的头发拉向 脱发或稀疏的点，对身体、社交、心理和健康造成损害 职业功能。针对 TTM 患者的经验支持的治疗方案是 严重受限。行为疗法是被证明有效的治疗方法之一。很遗憾， 行为疗法的局限性在于发展实时的拉力意识仍然存在 具有挑战性，缺乏广泛的可用性，而且通常成本很高。 假设：假设一种新颖的腕戴式设备和应用程序系统可用于 为拔毛癖提供习惯逆转疗法，这是行为疗法的关键组成部分。这 使用复杂的运动传感器和算法的设备可以被训练来检测 个人的拉动行为，从而实时增强意识。此外，它还可以检测 通过用户友好、功能丰富的移动应用程序来竞争响应并激发动力。 初步数据：调查小组的设备可以记录和检测运动并 方向，代表头发拉扯行为，可靠，每台机器测试。另外，在 在超过 90% 的病例中，可以可靠地检测到一个人玩弄眉毛的行为 类似行为的误报率可接受（30%）。 具体目标 1：设备准确检测 TTM 相关行为的能力将 建立并验证。该团队将 (1) 编目并记录进入的动作范围 TTM相关的拉动，以及（2）细化和测试设备的能力以准确检测 模拟和人体测试中的运动 具体目标 2：将 HabitAware 设备和随附的应用程序开发为独立的 利用专家告知的迭代过程提供自我管理的 HRT 系统 最终用户临床医生和 TTM 患者。 具体目标 3：团队将进行初步可行性、可用性和可接受性测试 HabitAware 设备用于确定后续步骤并推进第二阶段提案。 长期目标：我们的目标是开发一个用户友好、可广泛访问且负担得起的系统 通过提供实时拉扯意识的设备帮助治疗拔毛癖 行为和包含现有行为治疗协议元素的移动应用程序。