BU-UL Partnership to Enhance Emerging Epidemic Virus Research in Liberia (BULEEVR)

摘要 2013-2016年西非埃博拉病毒病（EVD）疫情显示，迫切需要改善 新出现的传染病的区域研究能力。尽管这一流行病造成了严重的人员伤亡， 当研究基础设施到位，以道德和适当的测试新的诊断， 医疗对策，疫情正在减弱。利比里亚，最近受埃博拉病毒病影响的国家之一 尽管最近成立了与艾滋病毒/艾滋病有关的研究财团， EVD在国内已经建立了一个潜在的平台，在此基础上可以建立进一步的方案。促进 在整个西非，特别是利比里亚，教育和研究基础设施将有多方面的发展， 效益首先，当疾病爆发时，由于预设的协议，它将提高试验的速度， 在国内的协议和培训。第二，国家研究人员的长期核心参与将 促进社区的信任和参与，协助成功执行审判。第三，研究基础设施 为支持新出现的病原体而建立的设施将用于应对其他地方性传染病。最后，促进和 先进的西非科学家允许基于调查的应用程序反映区域和当地的研究 施政纲要的演讲所有上述活动成功的基础是创建下一个 利比里亚调查员的一代。 波士顿大学（BU）和利比里亚大学（UL）与区域合作伙伴一起沿着提议建立一个 新出现的传染病分层研究培训计划，题为“波士顿大学， 利比里亚新出现的流行病病毒研究”（BULEEVR）计划，其框架是基于他们的 在授予该项目的D 71规划下进行的持续伙伴关系和广泛的需求评估 在2017-2018年。该BULEEVR计划将推进候选人与先前的硕士学位走向博士学位 学位和医学院毕业生通过科学硕士。除了产生调查员 具有适当的培训和经验，除了终端学位（谁最终可以申请 该计划将为正在进行的研究项目的参与者提供指导研究 从而在各国建立可持续性和保留知识资本。关于BULEEVR 该计划将包括在利比里亚举行的训练营， 翻译和临床研究，并将作为一个招聘池，从其中小选择程序， 然后，候选人可以在BU攻读高级学位。候选人随后将返回利比里亚， 研究经验。训练营将开放给有兴趣追求先进的候选人 学位以及其他有兴趣扩大他们的技能或知识基础的研究专业人员，或 通过提供的特定模块进行新方法的交叉培训。

Abstract The 2013-2016 Ebola Virus Disease (EVD) Epidemic in West Africa revealed the dire need for improved regional capacity for research in emerging infectious diseases. Despite the heavy human toll of the epidemic, by the time the research infrastructure was in place to ethically and appropriately test new diagnostics and medical countermeasures, the epidemic was waning. Liberia, one of the countries affected by the recent EVD epidemic, has a severe dearth of scientific capacity although recently founded research consortiums related to EVD in country have created a potential platform upon which further programs can be built. Fostering education and infrastructure for research in West Africa in general, and Liberia specifically, will have multifold benefits. First, it will increase the rapidity of trials when an outbreak occurs due to preset protocols, agreements and trainings in country. Second, the long term central involvement of national researchers will promote community trust and engagement, aiding successful execution of trials. Third, research infrastructure built to support emerging pathogens will address other endemic infectious diseases. Lastly, promoting and advancing West African scientists allows investigator based applications to reflect regional and local research agenda. The foundation for success of all of the above activities is a pipeline for the creation of the next generation of Liberian investigators. Boston University (BU) and University of Liberia (UL), along with regional partners propose the creation of a tiered research training program in emerging infectious diseases, entitled “Boston University-University of Liberia Emerging Epidemic Viruses Research” (BULEEVR) program, the framework of which is based on their on-going partnership and extensive needs assessment performed under a D71 planning awarded to the project in 2017-2018. The BULEEVR program will advance candidates with a prior Masters degree towards a doctoral degree and medical school graduates through a Masters in Science. In addition to generating investigators with the appropriate training and experience in addition to a terminal degree (who can eventually apply for independent funding), the program will foster mentored research for participants in ongoing research projects in Liberia, hence building both sustainability and retention of intellectual capital in country. The BULEEVR program will consist of a bootcamp held in Liberia which will provide a background in foundations of basic, translational and clinical research and will serve as a the recruitment pool from which small select program of candidates can then pursue an advanced degree at BU. The candidates will then return to Liberia for their research experience. The bootcamps will be open to both candidates interested in pursuing an advanced degree as well as other research professionals interested in expanding their skills or knowledge base, or to cross-train in a new methodology through a specific offered module.