BU-UL Partnership to Enhance Emerging Epidemic Virus Research in Liberia (BULEEVR)

摘要 2013-2016年西非的埃博拉病毒病(EVD)疫情表明，迫切需要改进 区域研究新发传染病的能力。尽管疫情造成了沉重的人员伤亡， 当研究基础设施就位时，从道德上适当地测试新的诊断和 医学对策，疫情正在消退。利比里亚，受最近埃博拉病毒影响的国家之一 流行病，严重缺乏科学能力，尽管最近成立了与以下方面有关的研究联盟 国家的环境与发展方案创造了一个潜在的平台，可以在此平台上开展更多的方案。养育 在整个西非，特别是在利比里亚，用于研究的教育和基础设施将有多个 福利。首先，当由于预设的方案而发生疫情时，它将提高试验的速度， 协议和在国内的培训。第二，国家研究人员的长期核心参与将 促进社区信任和参与，帮助成功执行试验。第三，研究基础设施 为支持新出现的病原体而建造的将解决其他地方性传染病。最后，促进和 先进的西非科学家允许基于调查员的应用程序反映区域和当地研究 议程。上述所有活动取得成功的基础是创建下一个活动的管道 一代利比里亚调查人员。 波士顿大学(BU)和利比里亚大学(UL)与区域合作伙伴提议建立一个 新兴传染病分级研究培训计划，题为“波士顿大学-华盛顿大学 利比里亚新出现的流行病病毒研究“(BULEEVR)计划，其框架是基于其 根据授予该项目的D71规划进行持续的伙伴关系和广泛的需求评估 2017-2018年。BULEEVR计划将使拥有硕士学位的候选人获得博士学位 理科硕士学位和医学院毕业生。除了产生调查人员 除了获得终极学位外，还要有适当的培训和经验(谁最终可以申请 独立资助)，该计划将为正在进行的研究项目的参与者培养有指导的研究 在利比里亚，因此在该国建立可持续发展和保留智力资本。BULEEVR 该计划将包括在利比里亚举办的训练营，该训练营将提供基本的、 翻译和临床研究，并将作为一个招募池，从小选择计划 然后，考生可以在波士顿大学攻读高级学位。然后，候选人将返回利比里亚参加他们的 研究经验。训练营将向两位有兴趣追求高级学位的候选人开放 学位以及其他有兴趣扩展自己的技能或知识库的研究专业人员，或 通过提供的特定模块交叉培训新的方法。

Abstract The 2013-2016 Ebola Virus Disease (EVD) Epidemic in West Africa revealed the dire need for improved regional capacity for research in emerging infectious diseases. Despite the heavy human toll of the epidemic, by the time the research infrastructure was in place to ethically and appropriately test new diagnostics and medical countermeasures, the epidemic was waning. Liberia, one of the countries affected by the recent EVD epidemic, has a severe dearth of scientific capacity although recently founded research consortiums related to EVD in country have created a potential platform upon which further programs can be built. Fostering education and infrastructure for research in West Africa in general, and Liberia specifically, will have multifold benefits. First, it will increase the rapidity of trials when an outbreak occurs due to preset protocols, agreements and trainings in country. Second, the long term central involvement of national researchers will promote community trust and engagement, aiding successful execution of trials. Third, research infrastructure built to support emerging pathogens will address other endemic infectious diseases. Lastly, promoting and advancing West African scientists allows investigator based applications to reflect regional and local research agenda. The foundation for success of all of the above activities is a pipeline for the creation of the next generation of Liberian investigators. Boston University (BU) and University of Liberia (UL), along with regional partners propose the creation of a tiered research training program in emerging infectious diseases, entitled “Boston University-University of Liberia Emerging Epidemic Viruses Research” (BULEEVR) program, the framework of which is based on their on-going partnership and extensive needs assessment performed under a D71 planning awarded to the project in 2017-2018. The BULEEVR program will advance candidates with a prior Masters degree towards a doctoral degree and medical school graduates through a Masters in Science. In addition to generating investigators with the appropriate training and experience in addition to a terminal degree (who can eventually apply for independent funding), the program will foster mentored research for participants in ongoing research projects in Liberia, hence building both sustainability and retention of intellectual capital in country. The BULEEVR program will consist of a bootcamp held in Liberia which will provide a background in foundations of basic, translational and clinical research and will serve as a the recruitment pool from which small select program of candidates can then pursue an advanced degree at BU. The candidates will then return to Liberia for their research experience. The bootcamps will be open to both candidates interested in pursuing an advanced degree as well as other research professionals interested in expanding their skills or knowledge base, or to cross-train in a new methodology through a specific offered module.