Nutrigenetics Core

项目摘要--营养遗传学核心 在这次竞争性的更新中，UNC NORC提议开发一种新的核心，即Nutrigenetics(NGx)核心，该核心 将帮助我们的研究基地确定影响个人需求的遗传因素和相互作用 对营养素的反应和肥胖的易感性，并确定预防和治疗的高效用目标 治疗。在接下来的5年里，这一核心将以每年55000美元的水平获得资助，预计 在此期间，核心将成熟并发展出一个示范的用户基础。NGx核心提供 服务包括i)协助提交赠款提案(假设开发、研究设计、POWER 计算和生成初步数据)；二)研究实施(收集数据和样本)；三) 实验室服务(样品处理、遗传和新陈代谢分析、化验经纪)；四)数据输入和 生物信息学服务；v)数据分析&成果的解释和传播。核心惠及广泛 一系列研究人员，如营养流行病学家、心理学家、遗传学家和医生，他们希望 通过将营养遗传学成分纳入人体研究来增强他们的科学能力。

Project Summary - Nutrigenetics Core In this competing renewal, the UNC NORC proposes to develop a new core, the Nutrigenetics (NGx) Core, that will assist our research base to identify genetic factors and interactions that affect an individual's needs and responses to nutrients and susceptibility to obesity, and to identify high-utility targets for prevention and treatment. During the next 5 years, this Core will be funded at a level of $55,000 per year, and it is expected that the core will mature and develop a demonstrated user base during this period. The NGx Core provides services including i) assistance with grant proposal submission (hypothesis development, study design, power calculations and generation of preliminary data); ii) study implementation (collection of data and samples); iii) laboratory services (sample processing, genetic and metabolic analyses, assay brokerage); iv) data entry and bioinformatics services; v) data analysis & interpretation and dissemination of results. The Core benefits a wide range of investigators such as nutrition epidemiologists, psychologists, geneticists and physicians who want to enhance their scientific capabilities by incorporating nutrigenetics components into human studies.