Transplant Infectious Diseases Interdisciplinary Research Training Grant

移植传染病跨学科研究培训补助金

• 批准号: 9761430
• 负责人: BARBARA D ALEXANDER
• 金额: $ 25.36万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9761430
• 关键词: Communicable Diseases; Grant; Interdisciplinary Study; Research Training; Transplantation

The Duke Transplant Infectious Diseases Training Program (TxIDTP) identifies talented young physicians knowledgeable in the clinical aspects of Infectious Diseases (ID) and provides them with advanced training in innovative methods of scientific research and the clinical care of the Transplant/Immunocompromised Host (ICH). Organ transplantation and cancer chemotherapy are life-saving interventions for an increasing number of patients. And while advances in surgical technique, cancer chemotherapy, and immunosuppressive drugs have improved the prognosis of transplant and hematologic malignancy patients, the majority of survivors remain at substantial risk for infection. Care of the complex ICH requires unique knowledge that differs from that of the general ID clinician; consequently, Transplant ID (TxID) has emerged as a subspecialty within ID. Further, physician-scientists, capable of bridging the link between medical research and clinical practice, are absolutely critical to understanding the epidemiology, unraveling the pathogenesis, improving the diagnosis, developing evidenced-based prevention and treatment plans, and responding to new infectious challenges as they emerge for this population. Duke University is uniquely poised to train such TxID physician-scientists. Duke Hospital is a major transplant and cancer care center with an active TxID clinical service, ACGME-accredited training programs in ID and Medical Microbiology, and a highly qualified faculty equipped and committed to teaching state- of-the-art methods of basic science and clinical/translational research. The objective of the TxIDTP is to capitalize on the rich resources available at Duke in order to develop innovative TxID physician-scientists. The combined research and clinical training occurs after completion of at least one year of general clinical ID fellowship. The program enrolls one new trainee per year and each trainee completes 3 years of training. The core curriculum includes training in the clinical care of the ICH and either basic or clinical/translational research individualized to the trainee's career goals. Key areas for research training, as applicable to the ICH, include: 1) microbial epidemiology and pathogenesis, 2) laboratory medicine, 3) host susceptibility and response to infection, and 4) medical management and treatment outcomes. Advanced degree options (e.g., Masters in Health Science) are available through the TxIDTP.

杜克移植传染病培训计划（TxIDTP）确定有才华的年轻医生 在传染病（ID）的临床方面的知识，并为他们提供先进的培训， 科学研究的创新方法和移植/免疫功能低下宿主的临床护理 （ICH）。器官移植和癌症化疗是越来越多的癌症患者的救命措施。 患者虽然外科技术、癌症化疗和免疫抑制药物的进步 改善了移植和恶性血液病患者的预后，大多数幸存者仍然在 有很大的感染风险。复杂ICH的护理需要独特的知识， 一般ID临床医生;因此，移植ID（TxID）已经作为ID内的子专业出现。此外， 医生科学家，能够弥合医学研究和临床实践之间的联系，绝对是 对于了解流行病学，揭示发病机制，改善诊断，开发 循证预防和治疗计划，并应对新出现的传染病挑战 对于这个人口。杜克大学是独一无二的准备培养这样的TxID医生科学家。杜克医院是 大型移植和癌症护理中心，提供活跃的TxID临床服务、ACGME认证的培训 ID和医学微生物学课程，以及配备并致力于教学状态的高素质教师- 基础科学和临床/转化研究的最先进方法。TxIDTP的目标是利用 利用杜克大学丰富的资源，培养创新的TxID医生科学家。将合并的 研究和临床培训发生在完成至少一年的一般临床ID奖学金之后。的 该计划每年招收一名新学员，每个学员完成3年的培训。核心课程 包括ICH临床护理培训以及个性化的基础或临床/转化研究， 学员的职业目标。适用于ICH的研究培训的关键领域包括：1）微生物 流行病学和发病机理，2）实验室医学，3）宿主易感性和对感染的反应，以及4） 医疗管理和治疗结果。高级学位选项（例如，健康科学硕士（Masters in Health Science） 通过TxIDTP。