FASEB SRC on Regulation of Glucose Metabolism: From Cell Biology to Systems Physiology

FASEB SRC 关于葡萄糖代谢的调节：从细胞生物学到系统生理学

• 批准号: 9762328
• 负责人: SCOTT A SUMMERS
• 金额: $ 1.47万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-06-01 至 2020-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9762328
• 关键词: Acceleration; Adipose tissue; American; Area; Biology; Biotechnology; Blood Glucose; Cardiovascular Diseases; Catabolic Process; Catalysis; Cell Proliferation; Cellular Metabolic Process; Cellular biology; Charge; Chronic Disease; Clinical; Cloning; Collaborations; Colorado; Complex; Data; Development; Diabetes Mellitus; Disease; Educational workshop; Emerging Technologies; Energy Metabolism; Epidemic; Event; Faculty; Fertilization; Funding; Genetic; Genetic Variation; Glucose; Glucose Transporter; Goals; Grouping; Health; Heart; Hour; Housing; Human; Individual; Industry; Institution; Investigation; Knowledge; Laboratories; Lead; Link; Liver; Maintenance; Malignant Neoplasms; Metabolic; Metabolic Control; Metabolism; Methodology; Methods; Mission; Mitochondria; Molecular; Myocardium; National Institute of Diabetes and Digestive and Kidney Diseases; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Oral; Participant; Pathway interactions; Pharmacologic Substance; Physiological; Physiology; Postdoctoral Fellow; Process; Protein Isoforms; Proteome; Recording of previous events; Regulation; Research; Research Personnel; Resort; Running; Science; Scientist; Senior Scientist; Series; Skeletal Muscle; Societies; Speed; Students; System; Systems Biology; Technology; Time; Tissues; Travel; Triglycerides; United States National Institutes of Health; Work; base; blood glucose regulation; capsule; career; career development; combat; cost; experience; genotypic sex; glucose disposal; glucose metabolism; glucose production; glucose transport; glucose uptake; human disease; insight; insulin signaling; lectures; meetings; member; metabolomics; minority student; mitochondrial metabolism; multidisciplinary; new product development; new therapeutic target; posters; programs; student participation; symposium; synergism; volunteer

Meeting Summary FASEB Summer Conference “Regulation of Glucose Metabolism: From Cell Biology to Systems Physiology” Snowmass Village, Colorado June 16-21, 2019 Scott Summers and Deobrah Muoio are pleased to co-chair the next Federation of American Societies for Experimental Biology (FASEB) conference on “Regulation of Glucose Metabolism - from Cell Biology to Systems Physiology” to be held at The Omni Rancho Las Palmas Resort & Spa, Rancho Mirage, CA from June 16-21, 2019. This is one of the longest-running and most venerable summer conferences in the history of the FASEB series, originally launched in 1993 in recognition of the cloning and characterization of a subset of the major glucose transporter isoforms. Over the ensuing years, the meeting has continued to feature important advances in glucose transporter biology, but has also evolved to embrace emergent topics in metabolic control mechanisms as they relate to chronic diseases and conditions such as obesity, diabetes, and cardiovascular disease. The meeting has consistently attracted major leaders in these fields, with considerable additional representation of emergent young scientists. This year’s program, as seen in the accompanying attachment, is no exception. Recent progress in this area of research has been explosive, and we believe that this meeting will be particularly timely in helping to fully appreciate the significance of recent developments. This year’s conference will provide a lively mix of glucose transporter biology, metabolic regulation, including application of “fluxomics” and systems biology methods in this arena, and multiple lectures that feature disease translational themes. A particular focus in 2019 will be the relation of glucose control mechanisms with mitochondrial biology, linking the proximal steps in glucose metabolism with terminal catabolic processes. The meeting will also include sessions on tissue-specific control mechanisms (e.g. adipose, liver, heart) as well as a new session on genetic diversity and sex in the modulation of glucose homeostasis, featuring scientists that lead this field as well as younger faculty in the early stages of their independent careers. We believe that the themes of the meeting are particularly well-aligned with challenges faced by the pharmaceutical and biotech industries in identifying new therapeutic targets that combat tractable disease mechanisms. We have invited approximately 40 scientists from institutions and companies worldwide to speak at the meeting, as well as an additional dozen prominent scientists to serve as session chairs and discussion leaders. In addition to these speakers we will be selecting approximately 16 short talks from abstracts to be presented by junior trainees. We will also run several poster sessions, and continuing a new and very well-received event launched at the 2013 meeting, we will have an “open mike” session of approximately 2 hours to allow volunteers to present particularly exciting data for discussion, with about 10 minutes per speaker. This year, we will pilot a "speed-dating" session to facilitate networking and encourage student participation from the very beginning of the meeting. We will also continue a career development workshop, started in 2017, that allowed senior scientists to share their experiences overcoming career hurdles.

会议纪要 FASEB夏季会议 “葡萄糖代谢的调节：从细胞生物学到系统生理学” 斯诺马斯村 2019年6月16日至21日 Scott Summers和Deobrah Muoio很高兴共同主持下一届美国社会联合会， 实验生物学（FASEB）会议“葡萄糖代谢的调节-从细胞生物学到 系统生理学”将在Omni Rancho Las帕尔马斯度假村和水疗中心，兰乔米拉奇，加利福尼亚州举行 2019年6月16日至21日这是一个最长的运行和最古老的夏季会议在 FASEB系列的历史，最初于1993年推出，以表彰克隆和表征一个 主要葡萄糖转运蛋白同种型的子集。在随后的几年里，会议继续 葡萄糖转运蛋白生物学的重要进展，但也演变为拥抱新兴的主题， 代谢控制机制，因为它们涉及慢性疾病和病症，如肥胖症、糖尿病， 心血管疾病会议一直吸引着这些领域的主要领导人， 新涌现的年轻科学家的代表。今年的节目，如在陪同 依恋，也不例外。最近在这一研究领域的进展是爆炸性的，我们认为， 这次会议将特别及时，有助于充分认识最近事态发展的重要性。 今年的会议将提供葡萄糖转运蛋白生物学，代谢调节，包括 “通量组学”和系统生物学方法在这一竞技场中的应用，以及以疾病为特色的多个讲座 翻译主题2019年的一个特别关注点将是葡萄糖控制机制与 线粒体生物学，将葡萄糖代谢的近端步骤与末端分解代谢过程联系起来。的 会议还将包括关于组织特异性控制机制（例如脂肪、肝脏、心脏）的会议，以及 一个关于葡萄糖稳态调节中的遗传多样性和性别的新会议， 领导这一领域以及年轻的教师在他们的独立职业生涯的早期阶段。我们认为 会议的主题特别符合制药和生物技术所面临的挑战， 工业界在确定新的治疗目标，打击易处理的疾病机制。 我们邀请了来自世界各地的机构和公司的大约40名科学家在 此外，还有12位杰出科学家担任会议主席和讨论领导人。 除了这些演讲者，我们将从摘要中选择大约16个简短的演讲 被初级学员我们还将运行几个海报会议，并继续一个新的和非常受欢迎的 在2013年会议上启动的活动中，我们将有一个大约2小时的“开放麦克风”会议， 志愿者提出特别令人兴奋的数据进行讨论，每个演讲者大约10分钟。今年以来， 我们将试行“速配”环节，以促进网络，并鼓励学生参与， 会议的开始。我们还将继续2017年开始的职业发展研讨会， 资深科学家分享他们克服职业障碍的经验。