Interdisciplinary Training Program in Metabolism

项目摘要 成立于2011年，犹他州大学跨学科T32培训计划在代谢准备 博士前和博士后学员在生物医学研究的成功职业生涯，使他们与 知识和科学专业知识，严格研究糖尿病，肥胖及其代谢基础， 并为他们提供领导和专业技能，以启动成功的研究 在学术界或工业界的职业生涯。该计划包括指导研究，职业发展活动， 和课程，同时为学员提供广泛的机会，与精英研究人员建立联系， 校园和地球仪。该计划利用犹他州的糖尿病和代谢的大学 研究中心（DMRC），作为该培训计划的基础设施。DMRC 通过促进丰富活动（例如，代谢研讨会 讲座系列，代谢研究进展会议，DMRC年度研讨会），管理 试点和可行性赠款，促进与DMRC相关的核心创新，促进招募新的 DMRC教师，并执行在线交流平台。该培训计划的主要内容包括 1)在基础和临床研究方面，以导师为基础的强大培训，2）严格的教学课程，包括 新陈代谢方面的核心课程以及研究方法和赠款撰写方面的具体培训，3）a 讲座系列侧重于新陈代谢与内部和外部扬声器，4）量身定制的职业指导， 个人发展计划，以确保成功过渡到职业生涯的下一阶段，以及4） 介绍和外联机会，以发展沟通技能。培训教师包括29名DMRC 成员拥有稳定的校外资金和来自八个部门的动态研究计划， 医学院、健康学院和药学院。这些参与的教师是 分为四个主题：细胞和分子机制，脂质代谢和脂肪生物学， 线粒体生物学，免疫机制，糖尿病并发症和血管生物学。 临床合格的学员是从内分泌学奖学金培训计划和博士博士后招募 都是在全国范围内招募到实验室的博士前候选人是从该计划招募， 分子生物学、生物化学、营养学和综合生理学。成功的申请者是 在该项目中获得了为期两年的任命。到目前为止，该方案已提供奖学金，并帮助 为16名博士后研究员和12名博士前实习生启动职业生涯。考虑到我们的毕业生人数 计划，增加DMRC教师的招聘，并增加申请人数，我们要求扩大 我们的计划，提供支持或四个博士前和三个博士后培训人员每年。这个程序 将由两名首席调查员和四个指导委员会组成的委员会监督 成员，他们都有很好的跟踪记录和承诺，指导学员。

PROJECT SUMMARY Established in 2011, the University of Utah Interdisciplinary T32 Training Program in Metabolism prepares predoctoral and postdoctoral trainees for successful careers in biomedical research, enabling them with the knowledge and scientific expertise to rigorously study the metabolic basis of diabetes, obesity and their comorbidities as well as providing them the leadership and professional skills to launch successful research careers in academia or industry. The program comprises mentored research, career development activities, and coursework while providing extensive opportunities for trainees to network with elite researchers on campus and around the globe. This program leverages University of Utah’s Diabetes and Metabolism Research Center (DMRC), which serves as the foundational infrastructure of this training program. The DMRC enriches the trainee experience through the facilitation of enrichment activities (eg. Seminars in Metabolism Lecture Series, Metabolism Research In Progress meetings, DMRC Annual Symposium), administration of pilot and feasibility grants, fostering innovation in DMRC-related cores, facilitation of the recruitment of new DMRC faculty, and execution of online communication platforms. Key elements in this training program include 1) strong mentor-based training in basic and clinical investigation, 2) rigorous didactic curriculum including a core curriculum in metabolism as well as specific training in research methodologies and grant writing, 3) a lecture series focused on metabolism with internal and external speakers, 4) tailored career mentoring with individual development plans to ensure a successful transition to the next stage of their career, and 4) presentation and outreach opportunities to develop communication skills. The training faculty include 29 DMRC members with stable extramural funding and dynamic research programs from eight departments within the School of Medicine, College of Health, and College of Pharmacy. These participating faculty members are organized into four themes: Cellular and Molecular Mechanisms, Lipid Metabolism and Adipose Biology, Mitochondrial Biology, Immunological Mechanisms, and Diabetes Complications and Vascular Biology. Clinically qualified trainees are recruited from fellowship training programs in Endocrinology, and PhD postdocs are recruited nationally into faculty laboratories. Predoctoral candidates are recruited from the programs in Molecular Biology, Biological Chemistry, and Nutrition and Integrative Physiology. Successful applicants are awarded a two-year appointment in the program. To date, the program has provided fellowships and helped to launch careers for 16 postdoctoral fellows and 12 predoctoral trainees. Given our expansion of graduate programs, increased recruitment of DMRC faculty, and increased number of applicants, we request expansion of our program to provide support or four predoctoral and three postdoctoral trainees annually. This program will be overseen by committee comprised of the two Principle Investigators and four Steering Committee Members, all of whom have strong track records and commitment to mentoring trainees.