Interdisciplinary Training Program in Metabolism

项目总结 犹他州大学新陈代谢跨学科T32培训计划成立于2011年，为 博士后和博士后实习生在生物医学研究领域取得成功，使他们能够 严格研究糖尿病、肥胖症及其代谢基础的知识和科学专业知识 以及为他们提供领导能力和专业技能，以开展成功的研究 在学术界或工业界的职业。该计划包括指导研究、职业发展活动、 和课程，同时为学员提供广泛的机会与精英研究人员建立网络关系 校园和世界各地。该项目利用犹他大学的糖尿病和新陈代谢 研究中心(DMRC)，它是本培训计划的基础设施。DMRC 通过促进充实活动丰富学员的经验(例如新陈代谢研讨会 系列讲座，代谢研究进展会议，DMRC年度研讨会)，管理 试点和可行性赠款，促进DMRC相关核心的创新，促进招聘新的 DMRC教职员工，以及在线交流平台的执行。本培训计划的主要内容包括 1)在基础和临床研究方面以导师为基础的强有力的培训，2)严格的教学课程，包括 新陈代谢核心课程以及研究方法和赠款撰写方面的具体培训，3)a 系列讲座集中于新陈代谢，内部和外部演讲者，4)量身定做的职业指导 个人发展计划，以确保成功过渡到其职业生涯的下一阶段，以及4) 提供演讲和外展机会，培养沟通技巧。培训人员包括29名DMRC 成员拥有稳定的外部资金和来自8个部门的动态研究计划 医学院、卫生学院和药学院。这些参与的教职员工是 分为四个主题：细胞和分子机制，脂肪代谢和脂肪生物学， 线粒体生物学，免疫机制，糖尿病并发症和血管生物学。 临床合格的实习生是从内分泌学和博士后研究员培训计划中招募的 在全国范围内被招募到教员实验室。博士后候选人是从#年的项目中招募的 分子生物学、生物化学、营养与综合生理学。成功申请者为 在该项目中获得了为期两年的任命。到目前为止，该方案提供了研究金，并帮助 启动16名博士后研究员和12名博士后实习生的职业生涯。考虑到我们扩大了毕业生人数 计划，增加DMRC教师的招聘，以及更多的申请者，我们要求扩大 我们计划每年提供四名博士后和三名博士后实习生的支持。本节目 将由两名首席调查员和四名指导委员会组成的委员会监督 成员，所有成员都有良好的记录和对指导学员的承诺。

PROJECT SUMMARY Established in 2011, the University of Utah Interdisciplinary T32 Training Program in Metabolism prepares predoctoral and postdoctoral trainees for successful careers in biomedical research, enabling them with the knowledge and scientific expertise to rigorously study the metabolic basis of diabetes, obesity and their comorbidities as well as providing them the leadership and professional skills to launch successful research careers in academia or industry. The program comprises mentored research, career development activities, and coursework while providing extensive opportunities for trainees to network with elite researchers on campus and around the globe. This program leverages University of Utah’s Diabetes and Metabolism Research Center (DMRC), which serves as the foundational infrastructure of this training program. The DMRC enriches the trainee experience through the facilitation of enrichment activities (eg. Seminars in Metabolism Lecture Series, Metabolism Research In Progress meetings, DMRC Annual Symposium), administration of pilot and feasibility grants, fostering innovation in DMRC-related cores, facilitation of the recruitment of new DMRC faculty, and execution of online communication platforms. Key elements in this training program include 1) strong mentor-based training in basic and clinical investigation, 2) rigorous didactic curriculum including a core curriculum in metabolism as well as specific training in research methodologies and grant writing, 3) a lecture series focused on metabolism with internal and external speakers, 4) tailored career mentoring with individual development plans to ensure a successful transition to the next stage of their career, and 4) presentation and outreach opportunities to develop communication skills. The training faculty include 29 DMRC members with stable extramural funding and dynamic research programs from eight departments within the School of Medicine, College of Health, and College of Pharmacy. These participating faculty members are organized into four themes: Cellular and Molecular Mechanisms, Lipid Metabolism and Adipose Biology, Mitochondrial Biology, Immunological Mechanisms, and Diabetes Complications and Vascular Biology. Clinically qualified trainees are recruited from fellowship training programs in Endocrinology, and PhD postdocs are recruited nationally into faculty laboratories. Predoctoral candidates are recruited from the programs in Molecular Biology, Biological Chemistry, and Nutrition and Integrative Physiology. Successful applicants are awarded a two-year appointment in the program. To date, the program has provided fellowships and helped to launch careers for 16 postdoctoral fellows and 12 predoctoral trainees. Given our expansion of graduate programs, increased recruitment of DMRC faculty, and increased number of applicants, we request expansion of our program to provide support or four predoctoral and three postdoctoral trainees annually. This program will be overseen by committee comprised of the two Principle Investigators and four Steering Committee Members, all of whom have strong track records and commitment to mentoring trainees.