International Congenital CMV Conference and CMV Workshop

国际先天性CMV会议及CMV研讨会

• 批准号: 9762502
• 负责人: Suresh B Boppana
• 金额: $ 2.95万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-02-18 至 2020-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9762502
• 关键词: AIDS/HIV problem; Address; Advocacy; Advocate; Affect; Allografting; Antiviral Agents; Area; Award; Basic Science; Child; Clinical; Clinical Research; Cognitive; Collaborations; Collection; Communities; Cytomegalovirus; Cytomegalovirus Infections; Cytomegalovirus Vaccines; Development; Disabled Children; Disease; Down Syndrome; Educational workshop; Environment; Family; Fetal Alcohol Syndrome; Fostering; Generations; Genetic Variation; Goals; Health; Health Policy; Human; Human Biology; Immune; Immune response; Individual; Infant; Institute of Medicine (U.S.); International; Intervention; Knowledge; Life; Live Birth; Maternal-Fetal Transmission; Molecular; Morbidity - disease rate; Motor; Neurodevelopmental Disability; Oral; Parents; Pathogenesis; Patients; Prevalence; Prevention; Prevention strategy; Public Health; Research; Research Personnel; Role; Scientist; Sensorineural Hearing Loss; Time; Translating; Translational Research; Translations; Travel; Vertical Disease Transmission; Virus Diseases; Vision; Woman; burden of illness; clinically relevant; congenital cytomegalovirus; congenital infection; disability; economic cost; effective intervention; experience; improved; innovation; interest; meetings; mortality; novel strategies; patient population; posters; pre-clinical research; prevent; programs; symposium; transmission process; virology; virus genetics; virus host interaction

ABSTRACT Human cytomegalovirus (CMV) is an important cause of invasive CMV disease in immune compromised individuals and a leading cause of congenital infection globally. Invasive CMV disease in patients with immune compromise results in significant morbidity and mortality. Congenital CMV infection is the leading non-hereditary hearing loss in children both in the U.S. and worldwide. It is estimated that between 3,000 and 6.000 children born annually in the U.S. experience long-term neurodevelopmental sequelae from congenital CMV infection. The 2019 CMV Conference (CMV2019) is the combined 7th biannual Congenital CMV Conference and the 17th International CMV Workshop. This integrated meeting brings together researchers working on all aspects of CMV disease, clinicians, public health policy experts and parents and advocates with a primary goal of reducing the disease burden from CMV infections. The topics that will be selected include those at the forefront of CMV research and the program is planned to disseminate new findings that can be translated to reduce or mitigate the consequences of CMV infections in immune compromised individuals and infants with congenital CMV infection. Topics will include (1) molecular mechanisms of CMV disease in various clinical settings, (2) pathogenesis of mother-to-child transmission of CMV, (3) virus-host interactions (4) cutting-edge knowledge on virus genetic diversity and its role in transmission and disease, and (5) effective intervention and prevention strategies to reduce the disease burden from CMV infection. In addition to the unique collection of research topics, this meeting provides a platform for new speakers, early stage investigators, and trainees. We will designate a proportion of invited presentations and session chairs for trainees or new investigators. Also, at least half of invited speakers and session chairs will be women. In addition to oral presentations, posters will be displayed throughout the conference and the two poster sessions will be held at the end of the day with extended periods of time for the presenters and attendees to interact and exchange ideas. By bringing the best of the CMV research community together, the overall goal of this conference is to advance the field towards innovative research and novel strategies for translating research findings to help alleviate the public health impact of CMV disease in all patient populations.

摘要 人巨细胞病毒（CMV）是免疫功能低下的巨细胞病毒病（CMV病）的重要病原 是全球先天性感染的主要原因。免疫患者的侵袭性巨细胞病毒疾病 损害导致显著的发病率和死亡率。先天性巨细胞病毒感染是主要的非遗传性 儿童听力损失在美国和世界各地。据估计，有3,000至6000名儿童 每年在美国出生的婴儿经历先天性CMV感染的长期神经发育后遗症。 2019年CMV会议（CMV 2019）是第7届两年一度的先天性CMV会议和第17届 国际CMV研讨会。这个综合会议汇集了研究人员的所有方面， CMV疾病，临床医生，公共卫生政策专家和父母以及倡导者的主要目标是减少 CMV感染的疾病负担。将被选中的主题包括那些在CMV的前沿 研究和计划，以传播新的发现，可以转化为减少或减轻 CMV感染对免疫受损个体和先天性CMV婴儿的影响 感染主题将包括（1）CMV疾病在各种临床环境中的分子机制，（2） CMV母婴传播的发病机制，（3）病毒-宿主相互作用，（4） 病毒遗传多样性及其在传播和疾病中的作用;（5）有效的干预和预防 减少CMV感染的疾病负担的策略。除了独特的研究收藏 主题，本次会议提供了一个平台，为新的发言者，早期研究者，和学员。我们将 为受训人员或新调查员指定一部分应邀发言和会议主席。另外，至少 受邀发言者和会议主席中有一半将是妇女。除了口头介绍，海报将 在整个会议期间展示，两个海报会议将在一天结束时举行， 演讲者和与会者互动和交流思想的时间。通过将最好的CMV 本次会议的总体目标是推动该领域朝着创新的方向发展。 研究和新的战略，转化研究成果，以帮助减轻CMV的公共卫生影响 所有患者群体的疾病。