International Congenital CMV Conference and CMV Workshop

国际先天性CMV会议及CMV研讨会

• 批准号: 9762502
• 负责人: Suresh B Boppana
• 金额: $ 2.95万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-02-18 至 2020-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9762502
• 关键词: AIDS/HIV problem; Address; Advocacy; Advocate; Affect; Allografting; Antiviral Agents; Area; Award; Basic Science; Child; Clinical; Clinical Research; Cognitive; Collaborations; Collection; Communities; Cytomegalovirus; Cytomegalovirus Infections; Cytomegalovirus Vaccines; Development; Disabled Children; Disease; Down Syndrome; Educational workshop; Environment; Family; Fetal Alcohol Syndrome; Fostering; Generations; Genetic Variation; Goals; Health; Health Policy; Human; Human Biology; Immune; Immune response; Individual; Infant; Institute of Medicine (U.S.); International; Intervention; Knowledge; Life; Live Birth; Maternal-Fetal Transmission; Molecular; Morbidity - disease rate; Motor; Neurodevelopmental Disability; Oral; Parents; Pathogenesis; Patients; Prevalence; Prevention; Prevention strategy; Public Health; Research; Research Personnel; Role; Scientist; Sensorineural Hearing Loss; Time; Translating; Translational Research; Translations; Travel; Vertical Disease Transmission; Virus Diseases; Vision; Woman; burden of illness; clinically relevant; congenital cytomegalovirus; congenital infection; disability; economic cost; effective intervention; experience; improved; innovation; interest; meetings; mortality; novel strategies; patient population; posters; pre-clinical research; prevent; programs; symposium; transmission process; virology; virus genetics; virus host interaction

ABSTRACT Human cytomegalovirus (CMV) is an important cause of invasive CMV disease in immune compromised individuals and a leading cause of congenital infection globally. Invasive CMV disease in patients with immune compromise results in significant morbidity and mortality. Congenital CMV infection is the leading non-hereditary hearing loss in children both in the U.S. and worldwide. It is estimated that between 3,000 and 6.000 children born annually in the U.S. experience long-term neurodevelopmental sequelae from congenital CMV infection. The 2019 CMV Conference (CMV2019) is the combined 7th biannual Congenital CMV Conference and the 17th International CMV Workshop. This integrated meeting brings together researchers working on all aspects of CMV disease, clinicians, public health policy experts and parents and advocates with a primary goal of reducing the disease burden from CMV infections. The topics that will be selected include those at the forefront of CMV research and the program is planned to disseminate new findings that can be translated to reduce or mitigate the consequences of CMV infections in immune compromised individuals and infants with congenital CMV infection. Topics will include (1) molecular mechanisms of CMV disease in various clinical settings, (2) pathogenesis of mother-to-child transmission of CMV, (3) virus-host interactions (4) cutting-edge knowledge on virus genetic diversity and its role in transmission and disease, and (5) effective intervention and prevention strategies to reduce the disease burden from CMV infection. In addition to the unique collection of research topics, this meeting provides a platform for new speakers, early stage investigators, and trainees. We will designate a proportion of invited presentations and session chairs for trainees or new investigators. Also, at least half of invited speakers and session chairs will be women. In addition to oral presentations, posters will be displayed throughout the conference and the two poster sessions will be held at the end of the day with extended periods of time for the presenters and attendees to interact and exchange ideas. By bringing the best of the CMV research community together, the overall goal of this conference is to advance the field towards innovative research and novel strategies for translating research findings to help alleviate the public health impact of CMV disease in all patient populations.

抽象的 人类巨细胞病毒（CMV）是免疫受损中侵袭性CMV疾病的重要原因 个人和全球先天感染的主要原因。免疫患者的侵入性CMV疾病 妥协导致明显的发病率和死亡率。先天性CMV感染是领先的非遗产 美国和全球儿童的听力损失。据估计，有3,000至6.000名儿童 每年在美国出生的人会从先天性CMV感染中经历长期神经发育后遗症。 2019 CMV会议（CMV2019）是联合第七次双年度先天性CMV会议和第17届会议 国际CMV研讨会。这次综合会议汇集了研究人员的研究人员 CMV疾病，临床医生，公共卫生政策专家和父母以及倡导者的主要目标是减少 CMV感染的疾病负担。将选择的主题包括CMV最前沿的主题 计划和该计划计划传播可以翻译以减少或减轻的新发现 先天性CMV的免疫受损的个体和婴儿中CMV感染的后果 感染。主题将包括（1）在各种临床环境中CMV疾病的分子机制，（2） CMV的母亲到儿童传播的发病机理，（3）病毒宿主相互作用（4）关于 病毒遗传多样性及其在传播和疾病中的作用，以及（5）有效的干预和预防 减轻CMV感染疾病负担的策略。除了独特的研究集合 主题，这次会议为新的演讲者，早期调查人员和学员提供了一个平台。我们将 为受训人员或新调查员指定一部分受邀演讲和会议主席。至少，至少 一半的演讲者和会议主席将是女性。除了口头演示外，海报还将 在整个会议期间展出，两次海报会议将在一天结束时进行延长 主持人和与会者互动和交流想法的时间。通过带来最好的CMV 研究社区在一起，这次会议的总体目标是将领域推进创新 研究和新的策略，用于翻译研究结果，以帮助减轻CMV的公共卫生影响 所有患者人群中的疾病。